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1.
Phys Med Biol ; 65(16): 165001, 2020 08 19.
Article in English | MEDLINE | ID: mdl-32422621

ABSTRACT

The commissioning and operation of a particle therapy centre requires an extensive set of detectors for measuring various parameters of the treatment beam. Among the key devices are detectors for beam range quality assurance. In this work, a novel range telescope based on a plastic scintillator and read out by a large-scale CMOS sensor is presented. The detector is made of a stack of 49 plastic scintillator sheets with a thickness of 2-3 mm and an active area of 100 × 100 mm2, resulting in a total physical stack thickness of 124.2 mm. This compact design avoids optical artefacts that are common in other scintillation detectors. The range of a proton beam is reconstructed using a novel Bragg curve model that incorporates scintillator quenching effects. Measurements to characterise the performance of the detector were carried out at the Heidelberger Ionenstrahl-Therapiezentrum (HIT, Heidelberg, GER) and the Clatterbridge Cancer Centre (CCC, Bebington, UK). The maximum difference between the measured range and the reference range was found to be 0.41 mm at a proton beam range of 310 mm and was dominated by detector alignment uncertainties. With the new detector prototype, the water-equivalent thickness of PMMA degrader blocks has been reconstructed within ± 0.1 mm. An evaluation of the radiation hardness proves that the range reconstruction algorithm is robust following the deposition of 6,300 Gy peak dose into the detector. Furthermore, small variations in the beam spot size and transverse beam position are shown to have a negligible effect on the range reconstruction accuracy. The potential for range measurements of ion beams is also investigated.


Subject(s)
Algorithms , Heavy Ion Radiotherapy/methods , Plastics , Radiation Monitoring/methods , Scintillation Counting/instrumentation , Telescopes/statistics & numerical data , Humans
2.
Rev. cuba. oftalmol ; 31(3): 1-7, jul.-set. 2018. tab
Article in Spanish | LILACS | ID: biblio-985574

ABSTRACT

Este estudio se propone conocer la ayuda visual mejor aceptada por pacientes de visión baja, para lo cual se realizó una revisión bibliográfica con el fin de contribuir al ejercicio optométrico. Se revisaron un total de 28 artículos del año 2007 a la fecha actual. En las diferentes patologías en estudio se encontró que la ayuda visual mejor aceptada para la visión cercana fueron las lupas, y para la visión lejana eran más usados los telescopios(AU)


The aim of this study is to determine which is the most frequent visual aid use in low vision. Twenty-eight articles were consulted in a period from 2007 until now. It was observed that for near vision the hans spectacles were the best aid and for far vision telescope were more used(AU)


Subject(s)
Humans , Vision, Low/etiology , Telescopes/statistics & numerical data , Education of Visually Disabled/methods , Helping Behavior , Review Literature as Topic , Scientific and Technical Publications
4.
Phys Med Biol ; 61(14): 5149-65, 2016 07 21.
Article in English | MEDLINE | ID: mdl-27352107

ABSTRACT

In order to exploit the advantages of ion-beam therapy in a clinical setting, delivery verification techniques are necessary to detect deviations from the planned treatment. Efforts are currently oriented towards the development of devices for real-time range monitoring. Among the different detector concepts proposed, Compton cameras are employed to detect prompt gammas and represent a valid candidate for real-time range verification. We present the first on-beam test of MACACO, a Compton telescope (multi-layer Compton camera) based on lanthanum bromide crystals and silicon photo-multipliers. The Compton telescope was first characterized through measurements and Monte Carlo simulations. The detector linearity was measured employing (22)Na and Am-Be sources, obtaining about 10% deviation from linearity at 3.44 MeV. A spectral image reconstruction algorithm was tested on synthetic data. Point-like sources emitting gamma rays with energy between 2 and 7 MeV were reconstructed with 3-5 mm resolution. The two-layer Compton telescope was employed to measure radiation emitted from a beam of 150 MeV protons impinging on a cylindrical PMMA target. Bragg-peak shifts were achieved via adjustment of the PMMA target location and the resulting measurements used during image reconstruction. Reconstructed Bragg peak profiles proved sufficient to observe peak-location differences within 10 mm demonstrating the potential of the MACACO Compton Telescope as a monitoring device for ion-beam therapy.


Subject(s)
Algorithms , Diagnostic Imaging/instrumentation , Image Processing, Computer-Assisted/methods , Phantoms, Imaging , Protons , Radiation Monitoring/instrumentation , Telescopes/statistics & numerical data , Gamma Rays/therapeutic use , Humans , Monte Carlo Method
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