ABSTRACT
Blood plasma thyroxine, triiodothyronine, thyroxine-binding globulin, and thyrotropic hormone have been radioimmunoassayed in 148 patients with rubromycosis. Reduced function of the thyroid has been detected in 39% of patients. Specific antifungal therapy does not essentially influence the function of the hypophyseal-thyroid system.
Subject(s)
Onychomycosis/physiopathology , Pituitary Gland, Anterior/physiopathology , Thyroid Gland/physiopathology , Tinea Pedis/physiopathology , Adult , Chronic Disease , Female , Foot Dermatoses/blood , Foot Dermatoses/physiopathology , Hand Dermatoses/blood , Hand Dermatoses/physiopathology , Humans , Male , Middle Aged , Onychomycosis/blood , Tinea Pedis/bloodABSTRACT
Examinations of 18 patients with mycoses of the foot complicated by allergic processes, have revealed elevated blood serum concentrations of histamine, serotonin, cathepsin D, and acid phosphatase, and a lowered activity of monoamine oxidase, as compared to 22 patients with mycoses not complicated with allergic manifestations. This fact reflects one of the aspects of a pathogenetic difference between these patients and necessitates combined therapy to correct the detected abnormalities.
