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1.
Rev. Assoc. Paul. Cir. Dent ; 70(3): 268-272, jul.-set. 2016. ilus
Article in Portuguese | LILACS, BBO - Dentistry | ID: lil-797081

ABSTRACT

Dente supranumerário é definido como um distúrbio de desenvolvimento caracterizado pela presença de um ou mais elementos dentários fora do número considerado normal de uma arcada. A ocorrência dos supranumerários pode ocasionar uma variedade de complicações, como por exemplo, apinhamento de dentes permanentes, erupção retardada e/ou ectópica, rotação dentária, formação de diastema, desenvolvimento de lesões císticas, reabsorção de dentes adjacentes. Na maioria das vezes o diagnóstico da presença desse elemento é realizado por exame clínico e radiográfico de rotina. O objetivo do presente trabalho foi relatar um caso clínico de retenção prolongada de um dente decíduo e erupção retardada de um dente permanente em decorrência da presença de um elemento supranumerário diagnosticado apenas aos 12 anos de idade. Após a identificação do elemento supranumerário e análise de exames radiográficos complementares,foi realizada cirurgia para remoção dos elementos decíduo e supranumerário, bem como acompanhamento por três meses do processo eruptivo do elemento impactado,um segundo pré-molar inferior direito o qual se posicionou favoravelmente na arcada dentária. Concluiu-se que a detecção em momento oportuno e a remoção de elementos supranumerários, também respeitadas à necessidade e oportunidade cirúrgica, são importantes para evitar danos futuros à oclusão dos pacientes, devendo-se dar importância ao acompanhamento e evolução clínica do caso.


Supernumerary teeth is defined as a developmental disorder characterized by the presence of one or more dental elements out of a number considered normal arch. The occurrence of supernumerary can cause a variety of complications, such as crowding of the permanent teeth,delayed and / or ectopically erupting, tooth rotation, diastema training, development of cysticlesions, resorption of adjacent teeth. In most cases the diagnosis of the presence of this elementis made by clinical examination and routine radiographic. The aim of this study was to reporta case of prolonged retention of a primary tooth eruption and delayed a permanent tooth dueto the presence of a supernumerary element diagnosed only 12 years old. After identifying the supernumerary element and analysis of complementary radiographs, it was carried out surgeryto remove the elements deciduous and supernumerary and monitoring for 3 months of the eruptive process impacted element, a premolar law that favorably-positioned in the dental arch.It was concluded that the timely detection and removal of supernumerary elements also respected the need and surgical opportunity, are important to prevent future damage to the occlusion of patients, should be given importance to the monitoring and clinical outcome.


Subject(s)
Humans , Male , Female , Child , Tooth, Impacted/classification , Tooth, Impacted/complications , Tooth, Impacted/diagnosis , Tooth, Impacted/prevention & control , Tooth, Supernumerary/complications , Tooth, Supernumerary/genetics , Tooth, Supernumerary/prevention & control , Tooth Eruption, Ectopic/complications , Tooth Eruption, Ectopic/diagnosis , Tooth Eruption, Ectopic/metabolism
2.
BMB Rep ; 41(4): 322-7, 2008 Apr 30.
Article in English | MEDLINE | ID: mdl-18452654

ABSTRACT

In this study, we compared the gene expression profiles of non-syndromic hyperplastic dental follicle (HDF) fibroblasts and normal dental follicle (NDF) fibroblasts using cDNA microarrays, quantitative PCR, and immunohistochemical staining. Microarray analysis showed that several collagens genes were upregulated in the HDFos, including collagen types I, IV, VIII, and XI and TIMP-1, -3, and -4 (fold ratio > 2.0). In contrast, the expression of MMP-1, -3, -10, and -16 together with IL-8 was more than two fold downregulated. The differential expression of the genes encoding alkaline phosphatase, MMP-1, -3, -8, and IL-8 was confirmed by quantitative RT-PCR, while that of 24 HDFs and 18 NDFs was confirmed by immunohistochemical analysis. However, HDFs showed stronger expression of MMP-3 than NDFs (P < 0.001). Collectively, these results indicate that defective regulation of MMPs mediating connective tissue remodeling may be responsible for abnormal tooth eruption.


Subject(s)
Dental Sac/pathology , Matrix Metalloproteinases/genetics , Tooth Eruption, Ectopic/genetics , Cells, Cultured , Dental Sac/metabolism , Down-Regulation , Gene Expression Profiling , Gene Expression Regulation, Enzymologic , Humans , Hyperplasia/genetics , Matrix Metalloproteinases/metabolism , Oligonucleotide Array Sequence Analysis , Tooth Eruption, Ectopic/metabolism
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