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1.
Sci Rep ; 11(1): 21483, 2021 11 02.
Article in English | MEDLINE | ID: mdl-34728721

ABSTRACT

With the development of material science, micro-nano-fabrication and microelectronics, the higher level requirements are posed on the electronic skins (E-skin). The lower energy consumption and multiple functions are the imperative requirements to spurred scientists and mechanists to make joint efforts to meet. To achieve lower energy consumption, a promising energy-harvesting style of triboelectric nanogenerators (TENG) is incorporated into the field effect transistors (FETs) to play the important role for sensor. For bifunctional sensor, to harness the difficult for reflecting the magnitude of frequency, we resorted to synaptic transistors to achieve more intelligentization. Furthermore, with regards to the configuration of FET, we continued previous work: using the electrolyte gate dielectrics of FET-ion gel as the electrification layer to achieve high efficient, compact and extensively adoption for mechanosensation. The working principle of the GFET was based on the coupling effects of the FET and the TENG. This newly emerged self-powered sensor would offer a new platform for lower power consumption sensor for human-machine interface and intelligent robot.


Subject(s)
Biosensing Techniques/instrumentation , Electric Conductivity , Electric Power Supplies/statistics & numerical data , Graphite/chemistry , Nanotechnology/instrumentation , Transistors, Electronic/statistics & numerical data , Wearable Electronic Devices , Humans
2.
Proc Natl Acad Sci U S A ; 118(39)2021 09 28.
Article in English | MEDLINE | ID: mdl-34544852

ABSTRACT

Electrode arrays are widely used for multipoint recording of electrophysiological activities, and organic electronics have been utilized to achieve both high performance and biocompatibility. However, extracellular electrode arrays record the field potential instead of the membrane potential itself, resulting in the loss of information and signal amplitude. Although much effort has been dedicated to developing intracellular access methods, their three-dimensional structures and advanced protocols prohibited implementation with organic electronics. Here, we show an organic electrochemical transistor (OECT) matrix for the intracellular action potential recording. The driving voltage of sensor matrix simultaneously causes electroporation so that intracellular action potentials are recorded with simple equipment. The amplitude of the recorded peaks was larger than that of an extracellular field potential recording, and it was further enhanced by tuning the driving voltage and geometry of OECTs. The capability of miniaturization and multiplexed recording was demonstrated through a 4 × 4 action potential mapping using a matrix of 5- × 5-µm2 OECTs. Those features are realized using a mild fabrication process and a simple circuit without limiting the potential applications of functional organic electronics.


Subject(s)
Action Potentials , Biosensing Techniques/methods , Induced Pluripotent Stem Cells/physiology , Myocytes, Cardiac/physiology , Transistors, Electronic/statistics & numerical data , Cells, Cultured , Electroporation , Humans , Induced Pluripotent Stem Cells/cytology , Myocytes, Cardiac/cytology
3.
Evol Comput ; 28(4): 677-708, 2020.
Article in English | MEDLINE | ID: mdl-32357077

ABSTRACT

For the first time, a field programmable transistor array (FPTA) was used to evolve robot control circuits directly in analog hardware. Controllers were successfully incrementally evolved for a physical robot engaged in a series of visually guided behaviours, including finding a target in a complex environment where the goal was hidden from most locations. Circuits for recognising spoken commands were also evolved and these were used in conjunction with the controllers to enable voice control of the robot, triggering behavioural switching. Poor quality visual sensors were deliberately used to test the ability of evolved analog circuits to deal with noisy uncertain data in realtime. Visual features were coevolved with the controllers to automatically achieve dimensionality reduction and feature extraction and selection in an integrated way. An efficient new method was developed for simulating the robot in its visual environment. This allowed controllers to be evaluated in a simulation connected to the FPTA. The controllers then transferred seamlessly to the real world. The circuit replication issue was also addressed in experiments where circuits were evolved to be able to function correctly in multiple areas of the FPTA. A methodology was developed to analyse the evolved circuits which provided insights into their operation. Comparative experiments demonstrated the superior evolvability of the transistor array medium.


Subject(s)
Robotics/instrumentation , Transistors, Electronic , Algorithms , Artificial Intelligence/statistics & numerical data , Avoidance Learning , Computer Simulation , Equipment Design , Genetic Phenomena , Humans , Neural Networks, Computer , Robotics/statistics & numerical data , Speech Recognition Software , Transistors, Electronic/statistics & numerical data
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