ABSTRACT
Non-gonococcal urethritis (NGU) is the most common disease of the genital tract in men. Recent studies have recommended avoiding the empiric antibiotic administrations that constitute the classical treatment approach in NGU and to aim toward treatment of causative pathogens. However, the classification of NGU agents remains controversial. In addition, the relevance of the commensalism of Mycoplasma hominis, Ureaplasma urealyticum, Ureaplasma parvum, and Gardnerella vaginalis, which are among the opportunistic pathogens found in the urethral flora, has yet to be determined. Furthermore, there are certain pathogens on which sufficient studies have not been conducted, although they are known to be NGU pathogens, and their statuses should be updated. In this review, the classification of NGU pathogens is summarized in the light of the current literature.
Subject(s)
Urethritis/classification , Urethritis/microbiology , Bacteria/isolation & purification , Humans , Viruses/isolation & purificationABSTRACT
No disponible
Subject(s)
Humans , Urethritis/classification , Gonorrhea/complications , Urethritis/etiology , Urethra/microbiology , Neisseria gonorrhoeaeABSTRACT
In this study, we used insurance claims for over one-third of the entire US population to create a subset of 128,989 families (481,657 unique individuals). We then used these data to (i) estimate the heritability and familial environmental patterns of 149 diseases and (ii) infer the genetic and environmental correlations for disease pairs from a set of 29 complex diseases. The majority (52 of 65) of our study's heritability estimates matched earlier reports, and 84 of our estimates appear to have been obtained for the first time. We used correlation matrices to compute environmental and genetic disease classifications and corresponding reliability measures. Among unexpected observations, we found that migraine, typically classified as a disease of the central nervous system, appeared to be most genetically similar to irritable bowel syndrome and most environmentally similar to cystitis and urethritis, all of which are inflammatory diseases.
Subject(s)
Disease/genetics , Environment , Genetic Predisposition to Disease/genetics , Insurance Claim Reporting/statistics & numerical data , Cystitis/classification , Cystitis/genetics , Disease/classification , Female , Humans , Inflammation/classification , Inflammation/genetics , Inheritance Patterns/genetics , Irritable Bowel Syndrome/classification , Irritable Bowel Syndrome/genetics , Linear Models , Male , Migraine Disorders/classification , Migraine Disorders/genetics , Multivariate Analysis , Pedigree , Risk Factors , United States , Urethritis/classification , Urethritis/geneticsSubject(s)
Lymphocytes/immunology , Urethritis/immunology , Humans , Immunophenotyping , Urethritis/classificationABSTRACT
The paper presents methods of Fuzzy Set Theory which can be a helpful key to medical diagnosis on the basis of symptoms as well as to the differentiating the effectiveness of action of drugs (metronidazole, tinidazole and ornidazole) in trichomoniasis. The relationship between patients and symptoms, symptoms and diagnoses or patients and diagnoses is considered as a fuzzy relation. A max-min composite fuzzy relation is a mathematical apparatus for finding the diagnoses such as: trichomoniasis, mycoses or bacterial infection. The solution of the other problem is based determining an eigen fuzzy set, associated with a given fuzzy relation, which can help to predict the theoretical maximal and minimal levels of recovery.
Subject(s)
Models, Theoretical , Trichomonas Infections/diagnosis , Trichomonas Vaginitis/diagnosis , Candidiasis, Vulvovaginal/diagnosis , Diagnosis, Differential , Female , Humans , Mathematics , Metronidazole/therapeutic use , Ornidazole/therapeutic use , Tinidazole/therapeutic use , Trichomonas Infections/classification , Trichomonas Infections/drug therapy , Trichomonas Vaginitis/classification , Trichomonas Vaginitis/drug therapy , Urethritis/classification , Urethritis/diagnosis , Urethritis/drug therapyABSTRACT
Se presenta la experiencia de 8 anos en el diagnostico de laboratorio de la uretritis masculina en la practica privada; en 1557 pacientes que tenian evidencias clinicas y de laboratorio de la enfermedad, se hallo un franco predominio de la forma no gonococica (81.0%). El examen directo con coloracion de Gram de la secrecion uretral o de la primera porcion de orina matinal fue de gran valor diagnostico tanto en la uretritis gonococica (UG) como en la no gonococica (UNG); la mayoria de los pacientes con UG tuvieron abundante secrecion; lo contrario ocurrido con los de UNG; solo en estos se hallaron secreciones acuosas o mucoides y fueron comunes las modalidades mixtas. Se hace enfasis en la necesidad de disponer de datos nacionales sobre la frecuencia relativa de la UNG y la UG, asi como de cultivos para Chlamydia y Ureaplasma con fines de investigacion. El laboratorio clinico, mediante la coloracion de Gram, puede hacer la distincion entre las dos formas de uretritis con prontitud, sencillez, economia y alto grado de confiabilidad
