ABSTRACT
Chromosomes of a ewe lamb born with atresia ani vaginalis were examined after a 72-hour culture of peripheral whole blood. The 2n number of chromosomes was 54,XX, with no apparent deviation from normality. Pedigree analysis of the ewe lamb indicated that her sire and dam were only slightly related (Rsd = 0.59%); therefore, the amount of inbreeding of the lamb was small (Fx = 0.30%).
Subject(s)
Chromosome Aberrations/veterinary , Rectal Fistula/veterinary , Sheep Diseases/genetics , Vaginal Fistula/veterinary , Animals , Chromosome Disorders , Female , Rectal Fistula/congenital , Rectal Fistula/genetics , Sheep , Sheep Diseases/congenital , Vaginal Fistula/congenital , Vaginal Fistula/geneticsABSTRACT
An abnormal chromosome No2 was found in the case of a child with an imperforate anus, a recto-vaginal fistula, unilateral atresia of the inner canal ,and deformity of the external ear. G-banding studies revealed an insertion of a segment of the short arm into the long arm in one of the chromosomes No. 2 of the proband, the apparent result of a de novo phenomenon of chromosome rearrangement.
