[Dna repair activity in children exposed to small doses of ionizing radiation as a result of the accident at the Chernobyl nuclear power station]. / Reparativnaia aktivnost' DNK u detei, podverzhennykh vozdeistviiu malykh doz ioniziruiushchego izlycheniia v rezultate avarii na Chernobyl'skoi AES.

The repair activity of DNA was studied by variola vaccine virus reactivation and induced mutagenesis tests in the peripheral blood lymphocytes of children living in areas with an increased level of ionizing radiation due to breakdown at the Chernobyl' nuclear power station. A more profound repair disturbance was revealed in children living on strictly controlled territories and born after the disaster, compared to those born before it, and children living in areas where the radiation level does not exceed background values. The disturbances were characterized by increased induced mutagenesis and decreased reactivation of the variola vaccine virus. No changes in the degree of DNA repair synthesis were registered in any of the groups studied.

[Interferon as a stimulator of DNA repair in patients with xeroderma pigmentosum]. / Interferon kak stimuliator reparatsii DNK u bol'nykh xeroderma pigmentosum.

Natural leucocyte interferon (IF) upon injection to two patients affected with Xeroderma pigmentosum for three weeks stimulated the inhibited DNA replication and Host reactivation at the level of healthy donors. Tigasol--the drug used traditionally for the treatment of diseases caused by Xeroderma pigmentosum proved less effective than IF.

[Malignant cell transformation in rats in vitro as affected by the variolovaccine virus]. / Zlokachestvennaia transformatsiia kletok krys in vitro pod vliianiem virusa ospovaktsiny.

The capacity of the variolovaccine virus with low cytopathogenic activity to cause morphologic and malignant transformation of normal rat cells in vitro is detected. The transformed cells induced tumours in gamma-irradiated rats.