ABSTRACT
We report a case of varicella-zoster vasculopathy that occurred in a 42-year-old renal transplant recipient with concurrent vertebral artery aneurysm and dissection. The patient was successfully treated with embolization and acyclovir therapy. Here, we review the English literature regarding the association of varicella-zoster virus infection with cerebral aneurysm.
Subject(s)
Herpes Zoster/complications , Herpesvirus 3, Human/isolation & purification , Intracranial Aneurysm/virology , Vertebral Artery/virology , Acyclovir/therapeutic use , Adult , Anticoagulants/therapeutic use , Antiviral Agents/therapeutic use , Embolism/prevention & control , Humans , MaleABSTRACT
This article reports a man who had herpes varicella zoster cervicalis with delayed stroke in the posterior circulation. Empiric treatment was acyclovir, methylprednisolone, and aspirin. Pontine infarction involving migration of the virus via cervicovascular innervation from C2 dorsal root ganglia to the vertebrobasilar circulation with attendant angiitis/angiopathy and thrombosis is proposed.
