Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 6 de 6
Filter
3.
Eur J Surg Oncol ; 44(3): 316-320, 2018 03.
Article in English | MEDLINE | ID: mdl-28343732

ABSTRACT

In recent years, the increasing numbers of small, apparently indolent thyroid cancers diagnosed in the world have encouraged investigators to consider non-intervention as an alternative to surgical management. In the following pages, the prospect of a non-intervention trial for thyroid cancer is considered with attention to the ethical issues that such a trial might raise. Such a non-intervention trial is analyzed relative to 7 ethical considerations: the social or scientific value of the research, the scientific validity of the trial, the necessity of fair selection of participants, a favorable risk-benefit ratio for trial participants, independent review of the trial, informed consent, and allowing the study participants to withdraw from the trial. A non-intervention trial for thyroid cancer is also considered relative to the central concept of equipoise.


Subject(s)
Clinical Trials as Topic/ethics , Ethics, Research , Informed Consent , Thyroid Neoplasms/pathology , Watchful Waiting/ethics , Disease Progression , Humans , Patient Selection/ethics , Prognosis , Research Design , Risk Assessment
SELECTION OF CITATIONS
SEARCH DETAIL
...