Subject(s)
Humans , Male , Adolescent , Weil Disease/complications , Weil Disease/diagnosis , Weil Disease/drug therapy , Weil Disease/diagnostic imaging , Shock, Septic/diagnosis , Zoonoses/epidemiology , Diagnosis, Differential , Fever/diagnosis , Leptospira interrogans/isolation & purification , Anti-Bacterial Agents/therapeutic useABSTRACT
In this report, we describe a case of Weil disease. Chest x-ray and computed tomography (CT) findings showed temporary deterioration 1 day after the initiation of antibiotic treatment, and high-resolution CT findings with the patient's physical findings made us suspect pulmonary alveolar hemorrhage (PAH). We believed that the PAH had been induced by Weil disease and subsequently caused Jarisch-Herxheimer reaction. We confirmed the patient's contact history with mice, and symptoms improved immediately after starting appropriate treatments. Leptospirosis is a relatively rare cause of PAH. Therefore, the possibility of this disease should be included in the differential diagnosis, especially when high-resolution CT findings indicate PAH, and the imaging findings deteriorate rapidly after antibiotic therapy.
Subject(s)
Occupational Diseases/diagnostic imaging , Tomography, X-Ray Computed , Weil Disease/diagnostic imaging , Adult , Animals , Anti-Bacterial Agents/adverse effects , Anti-Bacterial Agents/therapeutic use , Diagnosis, Differential , Hemoptysis/diagnostic imaging , Hemoptysis/etiology , Humans , Male , Mice , Occupational Diseases/complications , Occupational Diseases/drug therapy , Weil Disease/complications , Weil Disease/drug therapyABSTRACT
Weil disease is a rare and severe outcome of infection with leptospires. We report the radiographic appearance of this disease in a patient with hepatic, renal, and pulmonary involvement. Imaging findings added significantly to an early correct diagnosis and, thus, to immediate and successful therapy in this critically ill patient.
Subject(s)
Weil Disease/diagnosis , Adult , Humans , Kidney/diagnostic imaging , Liver/diagnostic imaging , Lung/diagnostic imaging , Male , Radiography , Ultrasonography , Weil Disease/diagnostic imagingABSTRACT
A consecutive series of 44 patients with proven leptospirosis was studied to document the radiographic pulmonary abnormalities, assess their prevalence, correlate them with the clinical signs and symptoms and determine their prognostic significance. Abnormalities were found in ten patients (23%), this prevalence being less than previously noted. The abnormalities shown were non-segmental opacification (consolidation-eight cases), basal linear opacities (collapse-five cases) and pleural effusions (four cases). The first radiographic demonstration of a large pleural effusion in leptospirosis is recorded. Non-jaundiced patients had a higher prevalence (43%) of these abnormalities than jaundiced (13%). No other correlation with clinical signs or symptoms was found. The presence of these abnormalities had no prognostic significance. It is concluded that the presence of radiographic pulmonary abnormality in in-patients with leptospirosis is common. These abnormalities are non-specific and can mimic other diseases leading to diagnostic difficulty. Such abnormalities may be extensive in the absence of clinical signs and symptoms.
Subject(s)
Leptospirosis/diagnostic imaging , Lung/diagnostic imaging , Adolescent , Adult , Aged , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Pleural Effusion/diagnostic imaging , Prognosis , Radiography , Weil Disease/diagnostic imagingABSTRACT
A consecutive series of 44 patients with proven leptospirosis was studied to document the radiographic pulmonary abnormalities, assess their prevalence, correlate them with the clinical signs amd symptoms and determine their prognostic significance. Abnormalities were found in ten patients (23 percent), this prevalence being less than previously noted. The abnormalities shown were non-segmental opacification (consolidation-eight cases), basal linear opacities (collapse-five cases) and pleural effusions (four cases). The first radiographic demonstration of a large pleural effusion in leptospirosis is recorded. Non-jaundiced patients had a higher prevalence (43 percent) of these abnormalities than jaundiced (13 percent). No other correlation with clinical signs or symptoms was found. The presence of these abnormalities had no prognostic significance. It is concluded that the presence of radiographic pulmonary abnormality in in-patients with leptospirosis is common. These abnormalities are non-specific and can mimic other diseases leading to diagnostic difficulty. Such abnormalities may be extensive in the absence of clinical signs and symptoms. (AU)
