Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add more filters










Database
Type of study
Language
Publication year range
1.
Transfusion ; 61 Suppl 1: S264-S274, 2021 07.
Article in English | MEDLINE | ID: mdl-34269447

ABSTRACT

Hemorrhage is a significant cause of death among military working dogs and in civilian canine trauma. While research specifically aimed at canine trauma is limited, many principles from human trauma resuscitation apply. Trauma with significant hemorrhage results in shock and inadequate oxygen delivery to tissues. This leads to aberrations in cellular metabolism, including anaerobic metabolism, decreased energy production, acidosis, cell swelling, and eventual cell death. Considering blood and endothelium as a single organ system, blood failure is a syndrome of endotheliopathy, coagulopathy, and platelet dysfunction. In severe cases following injury, blood failure develops and is induced by inadequate oxygen delivery in the presence of hemorrhage, tissue injury, and acute stress from trauma. Severe hemorrhagic shock is best treated with hemostatic resuscitation, wherein blood products are used to restore effective circulating volume and increase oxygen delivery to tissues without exacerbating blood failure. The principles of hemostatic resuscitation have been demonstrated in severely injured people and the authors propose an algorithm for applying this to canine patients. The use of plasma and whole blood to resuscitate severely injured canines while minimizing the use of crystalloids and colloids could prove instrumental in improving both mortality and morbidity. More work is needed to understand the canine patient that would benefit from hemostatic resuscitation, as well as to determine the optimal resuscitation strategy for these patients.


Subject(s)
Blood Transfusion/veterinary , Dog Diseases/therapy , Dogs , Resuscitation/veterinary , Shock, Hemorrhagic/veterinary , Wounds and Injuries/veterinary , Animals , Dog Diseases/blood , Dogs/blood , Dogs/physiology , Hemostasis , Humans , Shock, Hemorrhagic/blood , Shock, Hemorrhagic/therapy , Working Dogs/blood , Working Dogs/physiology , Wounds and Injuries/blood , Wounds and Injuries/therapy
2.
Vet Parasitol Reg Stud Reports ; 23: 100522, 2021 01.
Article in English | MEDLINE | ID: mdl-33678377

ABSTRACT

The protozoan Neospora caninum is an important cause of abortion in cattle worldwide, with domestic dogs serving as the definitive hosts. Although hunting activities have been indicated as a potential risk factor for N. caninum infection in dogs, no serological evidence has so far been reported in hunting dogs, wild boars (Sus scrofa), and hunters. A total of 98 wild boars, 168 hunting dogs, and 15 hunters from three Brazilian regions were sampled and tested for anti-N. caninum antibodies by indirect immunofluorescence antibody test, resulting in 15/168 (9%) seropositive hunting dogs, and 0/98 wild boars, and 0/15 hunters seropositive. The absence of N. caninum antibodies in wild boars may suggest low exposure to oocysts shed by hunting dogs and wild canids in three different Brazilian regions. Finally, the absence of hunter seropositivity supports the current lack of evidence that N. caninum is a zoonotic parasite.


Subject(s)
Antibodies, Protozoan/blood , Neospora , Sus scrofa/blood , Working Dogs , Animals , Brazil/epidemiology , Dogs , Seroepidemiologic Studies , Sus scrofa/immunology , Working Dogs/blood , Working Dogs/immunology
SELECTION OF CITATIONS
SEARCH DETAIL
...