Ellipsoidal Process of the Femoral Head in Legg-Calvé-Perthes Disease: Effect of Prophylactic Hemiepiphysiodesis.

Purpose: Legg-Calvé-Perthes disease (LCPD) often causes the residual deformity, typically appearing as an ellipsoidal shape. In some cases, this ovalization is related to the asymmetric growth of the femoral head physis, which presents a growth-inhibiting necrotic area in the anterosuperior quadrant. The objective of the present study is to evaluate the effectiveness of selective hemiepiphysiodesis of the healthy physis in the posteroinferior quadrant as a means of disrupting femoral head ovalization in cases of LCPD with the previous onset of ovalization. Methods: We performed a prospective study of 39 LCPD hips operated on consecutively by selective hemiepiphysiodesis of the posteroinferior portion of the head during the reossification phase.Surgical indication was based on a progressive increase in the ellipsoidal index (EI), the presence of a double epiphyseal nucleus of reossification, physeal narrowing, and physeal angulation. Hemiepiphysiodesis was performed at the mean patient age of 8.8 years (SD 1.5) and a mean of 4.7 years (SD 1.4) following disease onset. Results: Preoperative EI was 1.80 (SD 0.2), which was reduced to 1.72 (SD 0.2) postoperatively (P > 0.05). Physeal angulation increased from 50° preoperatively (SD 9.3) to 54.29° (SD 9.7) at the end of growth (P > 0.05). The final result according to the Stulberg classification revealed 20 class-II cases, 16 class III, and 3 class IV, and SDS was 25.97 (SD 9.95), range: 9.36-51.67. Conclusion: As revealed by the EI, the ellipsoidal process may be stopped by selective hemiepiphysiodesis in the posteroinferior quadrant of the femoral head. Level of Evidence: II.

Ellipsoidal process of the femoral head in Legg-Calvé-Perthes disease. Part I.

Legg-Calvé-Perthes disease (LCPD) often produces a residual deformity, typically consistent with coxa magna, coxa plana, and ellipsoidal shape. Depending on the degree of asphericity and flatness, this morphology was classified by Stulberg in stages III and IV. Thus far, few studies have investigated physeal injury as an etiological cause or evaluated its progressive profile throughout Waldenström's reossification stage and the remodelling stage. In this study, we analysed the ellipsoidal process of the femoral head. This was a retrospective control case study involving 83 unoperated hips with LCPD and Stulberg stages III and IV outcome. The data were compared with those obtained for 49 healthy contralateral hips (control). The Ellipsoidal Index, the presence of a double epiphyseal reossification nucleus, physeal narrowing, intraphyseal angle, epiphyseal height, diameter of the head, and Reimer's Index were determined. Measurements were performed at four-time points: the year the reossification stage was initiated, the final growth stage, and two equally spaced time points in between. The Ellipsoidal Index gradually increased throughout the course of the disease from 1.6 in the initial reossification stage to 2.0 at the end of growth. In the control cases, this value was consistently 1.4. More ellipsoidal deformity was observed in Stulberg stage IV versus Stulberg stage III patients (P < 0.05). Moreover, there was a direct link between a high Ellipsoidal Index and the appearance of a double reossification nucleus, a physeal narrowing in the area underlying the anterosuperior nucleus, intraphyseal angle. Reimer's Index showed a gradual extrusion from baseline to the end of growth (26.1 versus 31.8, respectively; P < 0.05). The ellipsoidal process of the femoral head occurs gradually throughout the reossification and remodelling stages. This was linked to the appearance of a double epiphyseal nucleus, gradual extrusion, an angulated physis appearance, an asymmetrical narrowing of the physis and a high Ellipsoidal Index, which may be indicative of poor prognosis. Levels of Evidence for Primary Research Question: Level III, case-control study.

Legg-Calvé-Perthes disease: role of isolated adductor tenotomy?

BACKGROUND: The aim of the study was to compare the radiological results at maturity of patients with Legg-Calve-Perthes disease, treated either by a uniform conservative treatment or by an adductor longus tenotomy. METHODS: The study cohort comprised 349 hips, mean age 4.4 years. Patients were classified in two different groups depending on the treatment performed. The conservative group (Group I) consisted of 318 hips that had been treated by physical therapy and abduction cast/brace, with a mean age 4.3 years (range 1-10). The tenotomy group (Group II) consisted of 31 hips (treated conservatively but developed an adduction contracture limited to 30°), which had been treated by adductor longus tenotomy with a mean age of 6.2 years (range 2-9). Hip range of motion and radiographic studies were performed at the time of admission. The extent of femoral epiphyseal involvement was assessed at each follow-up by the method of Herring. The final outcomes were assessed at skeletal maturity according to the Stulberg classification system. RESULTS: Only one patient (two hips) from Group II experienced an improvement in abduction, which was maintained throughout the follow-up until complete the healing of Legg-Calvé-Perthes disease was achieved. In the remaining 29 hips, we observed a progressive loss of ROM previous to 4.3 months from the tenotomy. According to the Stulberg classification, we did not find differences between both groups at final follow-up (p > 0.05). CONCLUSIONS: These preliminary data suggest that the isolated tenotomy of the adductor longus tendon does not modify the natural evolution of Legg-Calvé-Perthes disease.

Unicameral bone cyst: radiographic assessment of venous outflow by cystography as a prognostic index.

The aim of this study was to determine the benefits of cystography in the management of a simple bone cyst, its implication in the final result of the treatment after corticoid intracystic injections, and the presence of secondary effects. We retrospectively reviewed 42 patients diagnosed with a simple bone cyst. Cystography was performed before the corticoid injection. The presence or absence of loculation intracyst and the existence and number of venous outflows were determined. According to the venous drainage, cysts were classified as type 0 when a venous outflow did not exist and as type 1 when there was a rapid venous outflow (<3 min). The treatment protocol included a maximum of three corticoid injections at an interval of 6 months. Healing of the cyst was determined on the basis of Neer's criteria. Secondary effects and surgical complications were assessed. Cystography studies showed a unicameral bone cyst with absent loculation in 16 cases (37.3%), whereas the lesion showed multiloculation in 26 cases (62.7%). There was no statistical difference between loculation intracyst (present or absent) and the final outcomes of the 42 cysts treated with a steroid injection (P=0.9). Cystography showed a negative venogram in 10 cases (23.8%), whereas the cysts showed a rapid venous outflow in 32 cases (76.2%). On the basis of Neer's classification, all patients with a negative venogram achieved complete healing of the cyst. Patients with a rapid venous outflow achieved complete healing in 14 cases (Neer I). In two patients, the healing was incomplete at the end of the follow-up period (Neer IV). In most cases (21 cysts), healing was partial (Neer II). Five patients showed a recurrence after initial healing of the cyst (Neer III) (P<0.05). The number or the size of veins did not affect healing of a bone cyst (P=0.6). Two patients with a rapid venous outflow showed a generalized hypertrichosis after the first injection of corticosteroids. Sex and age at the initiation of the first injection were not significant factors of healing (P=0.4). The average follow-up time was 59 months (24-60 months). Cystography provides morphological and functional information of simple bone cyst. It is a useful test before the administration of percutaneous injections of sclerosing substances. It facilitates the differentiation of cysts that may achieve complete healing (negative venogram) from those that tend to show recurrence (rapid venous outflow). Therapeutic material should be introduced slowly and a second trocar should always be placed to decrease the risk of migration in cysts with communication with the venous system.

Juvenile osteochondritis dissecans of the knee: perifocal sclerotic rim as a prognostic factor of healing.

BACKGROUND: Management of osteochondritis dissecans of the femoral condyle in children remains uncertain. The aim of this study was to determine the presence of a perilesional sclerotic ring in radiologic examination and to establish its value for prognosis. METHODS: We retrospectively reviewed 85 patients diagnosed with osteochondritis dissecans. The population was distributed according to the grade of perilesional radiologic sclerosis: stage 0, patients who did not show a sclerotic rim in the anteroposterior and the lateral views; stage I, patients with marginal sclerosis only in 1 radiologic view; stage II, patients with sclerosis in both views. Patients were also distributed in different age groups: group 1, children under 12 years of age; group 2, children between 12 and 15 years of age; and group 3, children more than 15 years of age. These groups were correlated with the stage of perilesional sclerosis. Radiologic results were analyzed according to the Hughston scale after conservative or surgical treatment of the lesion. RESULTS: Lesions without perilesional sclerosis (stage 0) were cured in all the cases, with good results by means of conservative treatment (P<0.05). In patients with stage I or II perilesional sclerosis, the percentage of healing was smaller; in these cases, surgical treatment improved the results compared with those in which conservative treatment was used (P<0.05). Children under 12 years of age showed less perilesional sclerosis and more tendencies to spontaneous healing than those more than 15 years of age. In these patients, radiologic sclerosis is greater (P<0.05). CONCLUSIONS: The presence of a sclerotic rim in the osteochondritis dissecans lesions of the knees in children is considered a prognostic indicator of the process. Lesions without sclerosis show a tendency toward spontaneous recovery with conservative treatment. Lesions with perilesional sclerosis show worse evolution, and treatment with perforations is still essential for enhancement of healing. LEVEL OF EVIDENCE: Prognostic study, Level II (retrospective study).

Successful treatment of chronic recurrent multifocal osteomyelitis with indomethacin: a preliminary report of five cases.

Chronic recurrent multifocal osteomyelitis (CRMO) is a disease of children and young adults. Clinically, the disease is characterized by the insidious onset of local pain and swelling in affected bones. Its course is one of intermittent periods of exacerbation and remission with successive bones affected. The pathogenesis of CRMO remains unknown, although an autoinflammatory disorder may be the cause, with inflammation of bone. This lesion is radiologically characterized as multiple lucencies surrounded by defined zones of patchy but dense sclerosis, cortical thickening from periosteal new bone formation, and increased bone size with different bones involved. Multiple therapeutic regimens had shown only a partial or temporary response. Because indomethacin has been successfully applied in inhibition of ossification and inflammatory processes, we initiated therapy with indomethacin in patients with CRMO. We report on the cases of 5 patients who responded dramatically to treatment with indomethacin. All underwent progressive clinical improvement (mean, 2.8 months). Radiological lesions disappeared after a mean period of 10.5 months. In 1 case where treatment was started late, small osteolytic zones persisted but with no clinical consequences. There were no additional recurrences or new bones affected during follow-up period (mean, 4 years). Our observation indicates that indomethacin may be an effective treatment for CRMO.