Hypothalamic control of adipose tissue.

A detailed appreciation of the control of adipose tissue whether it be white, brown or brite/beige has never been more important to the development of a framework on which to build therapeutic strategies to combat obesity. This is because 1) the rate of fatty acid release into the circulation from lipolysis in white adipose tissue (WAT) is integrally important to the development of obesity, 2) brown adipose tissue (BAT) has now moved back to center stage with the realization that it is present in adult humans and, in its activated form, is inversely proportional to levels of obesity and 3) the identification and characterization of "brown-like" or brite/beige fat is likely to be one of the most exciting developments in adipose tissue biology in the last decade. Central to all of these developments is the role of the CNS in the control of different fat cell functions and central to CNS control is the integrative capacity of the hypothalamus. In this chapter we will attempt to detail key issues relevant to the structure and function of hypothalamic and downstream control of WAT and BAT and highlight the importance of developing an understanding of the neural input to brite/beige fat cells as a precursor to its recruitment as therapeutic target.

A literature-based approach to teaching values to adolescents: does it work?

Articles advocating the use of literature to accomplish a variety of goals is common in journals of educational psychology and social work. However, studies validating such an approach are scarce. This study attempts to assess the effectiveness of one reading project to teach one specific value. Using an experimental design in a 7th grade classroom, the researchers introduced the reading project as the independent variable, and measured the dependent variable, the value of caring for others, with a series of essays. The results of the experiment indicate moderate support for the use of literature-based approach to teaching values. Changes from pretest to posttest in two of the three essays were in the hypothesized direction, However, the authors advise practitioners that the use of one discrete project cannot produce large-scale or long-term change.

Adolescence: a literary passage.

Using Erikson's and Gilligan's theories of adolescent development, this paper presents a content analysis of the depiction of adolescent development in a sample of Newbery Medal winners and honor books. Some diversity was found among the major characters, but white males were overrepresented. Many of the characters underwent an identity crisis. Some passed through the identity versus role confusion stage; others, especially in the almost prototypical male-initiation-rite stories, discovered ways to deal with nature (industry) which engendered a far clearer sense of self (identity). The major female characters experienced the two phases more or less simultaneously, but a similar fusion existed for a number of the male characters. The themes of "separation" and "connection" were paramount in the stories, and what Gilligan has called "the ethic of care" was presented positively. Some main characters matured only when they recognized their responsibility to others.