[Mental changes in course of pituitary gland tumour--a case study]. / Zmiany psychiczne u chorego z guzem przysadki mózgowej--opis przypadku.

The aim of this paper is to present a case of a 59-year old patient diagnosed with a pituitary gland tumour. The psychiatric examination at the day of admission to the clinic suggested the manic episode was based upon the disseminated organic brain lesion. The patient presented mood elevation, carefree joviality, excitement, loss of social inhibition, inability to sustain attention. In course of the clinical observation and diagnostic progress the pituitary gland tumour was revealed and neurosurgical treatment was applied. The psychopathological course of the disorder was not typical for the established location. The psychopathological syndrome that was presented by the patient gave the global clinical impression of frontal and temporal lobes' dysfunction. This case report supports the present neurobiological opinions criticizing the direct relation of the location to the function within the central nervous system.

[Quality of life and therapy in the elderly patients on chronic peritoneal dialysis]. / Jakosc terapii i jakosc zycia u chorych w podeszlym wieku leczonych dializa otrzewnowa.

UNLABELLED: In this study quality of life adequacy of treatment was assessed in 32 PD patients over 65 years of age and compared with younger patients on PD (age 40 on average). Quality of life was examined with help of QLQ-C30 questionnaire, negative emotions with use of HADS and own Aggression Scale, life satisfaction on the Cantril's Ladder. Total weekly clearances were used for adequacy assessment as well as nutrition parameters and rate of anaemia and EPO use. Frequency of complications was also compared. Elderly patients were starting dialysis with lower GFR, but in the course of observation neither total clearances nor nutrition parameters and degree of anaemia did not differ between the groups. Elderly used EPO significantly less frequently in comparison to the younger patients. Peritonitis rate was similar and exit site infections were less frequent in elderly population. There was no difference between quality of life and level of negative emotions between the groups. IN CONCLUSION: PD appears to be effective and acceptable method of dialysis for the elderly.

[Carbamazepine in the treatment in psychiatric disorders based on retrospective clinical study]. / Karbamazepina w leczeniu zaburzen psychicznych na podstawie wlasnego materialu klinicznego.

Medical records of patient treated in I Department of Psychiatry Medical University of Gdansk in 1996-2000 were analysed. Carbamazepine was used in 383 patients, 209 male and 174 female. Mean age for the whole group 41.2 years, for male 40.6, for female 41.9. Carbamazepine was mainly used in affective disorders (F30-33) and organic affective disorders (F06.3)-107 persons. Second the most common indication was organic personality disturbances (F07.0)-121 persons. Carbamazepine was used in 100-1200 mg per day (mean dose 415 mg) during 5-189 days (mean 36 days). Treatment was well tolerated. Only 24 patients (6.3%) have mild side effects. Drug level in blood was checked in 19 patients during two last years of analysed material. Carbamazepine was used mainly with tricyclic antidepressants (30.3%), second generation antidepressive drugs (22.2%) and typical neuroleptics (11.1%). More than half of patients (55.6%) were recovered. Based on clinical material carbamazepine seems to be active agent in treatment of affective disorders and diseases connected with organic brain lesion.