RESUMEN
We carried out a prospective randomized trial on 220 couples with nontubal factor infertility to compare pregnancy rates and implantation rates after zygote intrafallopian transfer (ZIFT) and uterine embryo transfer (UET). The zygote was transferred by laparoscopy into the fallopian tube 24 hours after oocyst retrieval. UET was performed 72 hours after retrieval with abdominal sonography guide. Transfer was performed in 102 cycles in the ZIFT and 100 cycles in the U ET group. The pregnancy and implantation rates were significantly higher in the ZIFT group (42.1% and 11.7%) than in the UET group (21.0% and 7.8%) (P < 0.05). ZiFT could be considered for couples who have limited time and adequate financial support.
Asunto(s)
Implantación del Embrión , Transferencia de Embrión/métodos , Infertilidad Femenina/terapia , Resultado del Embarazo/epidemiología , Transferencia Intrafalopiana del Cigoto/métodos , Adulto , Índice de Masa Corporal , Femenino , Humanos , Infertilidad Femenina/etiología , Irán/epidemiología , Inducción de la Ovulación/métodos , Selección de Paciente , Embarazo , Índice de Embarazo , Embarazo Múltiple , Estudios Prospectivos , Factores de Tiempo , Resultado del TratamientoRESUMEN
We carried out a prospective randomized trial on 220 couples with nontubal factor infertility to compare pregnancy rates and implantation rates after zygote intrafallopian transfer [ZIFT] and uterine embryo transfer [UET]. The zygote was transferred by laparoscopy into the fallopian tube 24 hours after oocyst retrieval. UET was performed 72 hours after retrieval with abdominal sonography guide. Transfer was performed in 102 cycles in the ZIFT and 100 cycles in the UET group. The pregnancy and implantation rates were significantly higher in the ZIFT group [42.1% and 11.7%] than in the UET group [21.0% and 7.8%] [P < 0.05]. ZIFT could be considered for couples who have limited time and adequate financial support
Asunto(s)
Implantación del Embrión , Transferencia de Embrión , Infertilidad Femenina , Estudios Prospectivos , Índice de EmbarazoRESUMEN
OBJECTIVE: The aim of this double-blind and placebo-controlled trial was to investigate whether saffron (stigma of Crocus sativus L.) could relieve symptoms of premenstrual syndrome (PMS). DESIGN: Double-blind, randomised and placebo-controlled trial. SETTING: Departments of Gynaecology/Obstetrics and Psychiatry, Tehran and Zanjan University of Medical Sciences. POPULATION: Women aged 20-45 years with regular menstrual cycles and experience of PMS symptoms for at least 6 months were eligible for the study. METHOD: Women were randomly assigned to receive capsule saffron 30 mg/day (15 mg twice a day; morning and evening) (group A) or capsule placebo (twice a day) for a two menstrual cycles (cycles 3 and 4). MAIN OUTCOME MEASURES: The primary outcome measure was the Daily Symptom Report, and secondary outcome measure was the Hamilton Depression Rating Scale. RESULTS: In this trial, saffron was found to be effective in relieving symptoms of PMS. A significant difference was observed in efficacy of saffron in cycles 3 and 4 in the Total Premenstrual Daily Symptoms and Hamilton Depression Rating Scale. CONCLUSION: The results of this study indicate the efficacy of C. sativus L. in the treatment of PMS. However, a tolerable adverse effects profile of saffron may well confirm the application of saffron as an alternative treatment for PMS. These results deserved further investigations.
