RESUMEN
The clinical picture of different forms of diffuse periaxial encephalitis (DPE)--encephalic, pseudotumorous and psychic--is described. The authors present criteria of the diagnosis of each of these forms and their differentiation from other clinically similar diseases (viral encephalitides, brain tumours and psychoses). They also outline the signs distinguishing DPE from multiple sclerosis and to a certain degree from leukodystrophies.
Asunto(s)
Esclerosis Cerebral Difusa de Schilder/diagnóstico , Adolescente , Adulto , Neoplasias Encefálicas/diagnóstico , Enfermedades Arteriales Cerebrales/diagnóstico , Diagnóstico Diferencial , Errores Diagnósticos , Encefalomielitis/diagnóstico , Femenino , Humanos , Esclerosis Múltiple/diagnóstico , Esquizofrenia/diagnóstico , Vasculitis/diagnósticoRESUMEN
The data obtained by the authors refute the generally accepted opinion to the effect that Schilder's encephalitis is a very rare disease predominantly affecting children. Clinical and neurohistological examinations of 16 patients have made it possible to establish that demyelinization foci may affect all portions of the brain, being found, however, more commonly in the frontal and occipital lobes, basal ganglia and brain stem. The spinal cord is also frequently involved. The clinical picture of the disease is polymorphic and reflects multiple lesions of the associative and projectional conductive pathways. The most consistent findings include mental disturbances and symptoms of pyramidal tract affection. The development and course of the disease are variable. In some cases long-term relapses may develop.
Asunto(s)
Encéfalo/patología , Esclerosis Cerebral Difusa de Schilder/diagnóstico , Adolescente , Adulto , Esclerosis Cerebral Difusa de Schilder/complicaciones , Esclerosis Cerebral Difusa de Schilder/patología , Ecoencefalografía , Electroencefalografía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Trastornos del Movimiento/etiología , Trastornos del Habla/etiología , Médula Espinal/patología , Trastornos de la Visión/etiologíaRESUMEN
The authors observed 16 patients suffering from nodular periarteritis with the polyneuritis syndrome. The development and clinical characteristics of polyneuritis due to nodular periarteritis were studied, its course and outcome were also recorded. Some data helpful for recognizing the etiology of polyneuritis are presented. It is demonstrated that when multiple modality treatment (with corticosteroids as a component) is initiated at the early stages of disease, some patients exhibit prolonged remission of nodular periarteritis, including notable regression of polyneuritis manifestations.