Delivering computationally-intensive digital patient applications to the clinic: An exemplar solution to predict femoral bone strength from CT data.

BACKGROUND AND OBJECTIVE: Whilst fragility hip fractures commonly affect elderly people, often causing permanent disability or death, they are rarely addressed in advance through preventive techniques. Quantification of bone strength can help to identify subjects at risk, thus reducing the incidence of fractures in the population. In recent years, researchers have shown that finite element models (FEMs) of the hip joint, derived from computed tomography (CT) images, can predict bone strength more accurately than other techniques currently used in the clinic. The specialised hardware and trained personnel required to perform such analyses, however, limits the widespread adoption of FEMs in clinical contexts. In this manuscript we present CT2S (Computed Tomography To Strength), a system developed in collaboration between The University of Sheffield and Sheffield Teaching Hospitals, designed to streamline access to this complex workflow for clinical end-users. METHODS: The system relies on XNAT and makes use of custom apps based on open source software. Available through a website, it allows doctors in the healthcare environment to benefit from FE based bone strength estimation without being exposed to the technical aspects, which are concealed behind a user-friendly interface. Clinicians request the analysis of CT scans of a patient through the website. Using XNAT functionality, the anonymised images are automatically transferred to the University research facility, where an operator processes them and estimates the bone strength through FEM using a combination of open source and commercial software. Following the analysis, the doctor is provided with the results in a structured report. RESULTS: The platform, currently available for research purposes, has been deployed and fully tested in Sheffield, UK. The entire analysis requires processing times ranging from 3.5 to 8 h, depending on the available computational power. CONCLUSIONS: The short processing time makes the system compatible with current clinical workflows. The use of open source software and the accurate description of the workflow given here facilitates the deployment in other centres.

A survey in the West Midlands on the use of the courtesy title 'Dr' by UK dental practitioners.

OBJECTIVE: To assess the 1995 General Dental Council's decision to remove restrictions on GDPs using the courtesy title 'Dr'. METHODS: In 1996 this survey undertook a qualitative analysis of the views of four groups involved in primary dental care: 72 GDPs, 25 medical practitioners, 46 vocational dental practitioners, 89 patients. RESULTS: These indicated that some respondents thought that there would possibly be better quality of patient care due to improved medical history taking, that the public's image of the dental profession might be enhanced and that 87% of newly qualified dentists were in favour of the use of the title 'Dr'. CONCLUSIONS: Use of the title appears to be on the increase and if use of the title does become widespread, then all practitioners will need to re-evaluate their choice of personal titles. GDPs need to consider if using the title 'Dr' will encourage patients to give more detailed medical histories.

Survey of the use of personal protective equipment and prevalence of work related symptoms among dental staff.

OBJECTIVES: Dental instruments such as the right angle or straight handpiece, air turbine, and ultrasonic scaler have the ability to produce dental aerosols containing water, saliva, microorganisms, blood, tooth particles, lubricating oil, and restorative materials. The purpose of this study was to find out whether personal protective equipment (mask, glasses) was used by dental personnel, and to investigate possible work related disease in the dental profession. METHODS: Cross sectional data were collected with a self administered questionnaire sent to 69 randomly chosen general dental practices in the West Midlands Region. All members of the dental team completed questionnaires (dentists (n = 122); nurses (n = 115); hygienists (n = 86); and receptionists (n = 74) and answered questions on use of personal protective equipment and the prevalence of upper and lower respiratory tract, eye, and skin symptoms (reported and work related). Reception staff were included as a low exposure, control group. Also, a longitudinal study of dental hygienists was carried out on 31 people who had taken part in a similar study five years earlier. RESULTS: Use of a face mask and glasses differed between clinical groups with hygienists and nurses being the most and least prevalent users respectively. Although several reported symptoms were significantly more prevalent among clinical staff, only one work related symptom (skin rashes or itchy or dry skin) was reported by the clinical staff more than by the non-clinical receptionists. Among female clinical staff, age < 35 years and atopy were the factors that predisposed to work related symptoms. Also, reported symptoms were related to duration of use of instruments that generated aerosols. CONCLUSIONS: This study shows a low level of work related symptoms in dentistry, but highlights a group vulnerable to prolonged exposures to dental aerosols. It also supports the need for enforcement of the use of personal protective equipment among dental nurses.

The vocational training scheme: decision-making in relation to general dental practitioners participating as scheme trainers.

In recent years, well-documented changes have occurred in the patterns of oral disease and, as a result, the scope and complexity of dental treatments has widened considerably. In response to this the Department of Health has introduced a compulsory one-year postgraduate vocational training scheme [VTS]. In this scheme, new graduates spend time in approved general dental practices, trained by selected general dental practitioners [GDPs] who are seen as having 'best practice' standards. For the VTS to succeed it will require the continued support of these 'best quality' GDPs who at the moment are competing for places as trainers. Such competition has not always existed and this paper describes a decision-making model for trainers which was developed because future external influences could reverse this competitive scenario, with a major effect on the postgraduate training programme.

Safety in the presence of lightning.

Not enough emphasis is usually placed on the proactive ability to recognize the lightning hazard. Instead, most literature and training materials treat the reactive mode. The latter approach emphasizes the posture to take when a person is caught by surprise in the open by a thunderstorm when the lightning threat is at its greatest; in other words, it is too late for precautions. The same reactive approach concentrates on what a person is wearing or holding when lightning is overhead instead of how the person came to be in this situation in the first place. Rather than focusing on these last-minute factors, the primary issue must be on the ability of a person, whether in a baseball game, riding a bike, or on a golf course, to recognize in advance the existence of a major lightning threat. This proactive approach emphasizes advance planning and recognition of a potential threat from lightning. A complete plan involves a sequence of decisions on a time scale from days to seconds. Although most of the available information in pamphlets and safety guidelines is correct concerning the reactive phase of lightning safety, the hazard remains important because of the lack of emphasis on planning and awareness.

Extraversion, neuroticism, and verbal reasoning ability as determinants of paired-associates learning.

Predictions based on theories of verbal learning proposed by Spence and Eysenck were compared by using a non-competitive list of paired-associates formed from seven synonym pairs, and a competitive list formed by pairing each of the seven S words with a R word with which it was not synonymous. Each list was presented in a 2x2x2 design to groups of primary school children differing in extraversion, neuroticism, and verbal reasoning ability. Performance on both lists was related to ability level and extraversion, and these relationships did not interact with the stage of learning. It is concluded in support of Eysenck's theory that differences in extraversion are of importance in determining performance on such tasks.