Histologic evaluation of radiofrequency ablation in renal cancer.

AIM: To report on the histologic evaluation of renal tumors after intraoperative radiofrequency ablation (RFA) performed immediately before surgical nephrectomy. MATERIALS AND METHODS: Ten patients with renal tumors were studied. All tumors were confirmed to be renal cell carcinoma before radio frequency ablation treatment. All specimens were stained with hematoxylin and eosin and nicotinamide adenine dinucleotide (NADH). RESULTS: Mean tumor size was 29 mm (range 14 to 48 mm). Of the 10 tumors 5 were completely devitalized with a treatment margin ranged from 1 to 20mm. One tumor needed two treatment sessions. No complication related to radiofrequency treatment was recorded. CONCLUSIONS: Our data indicate that RFA can completely destroy renal tumors. However, in our study, complete tumor cell death was obtained only in 50% of cases. More studies are needed to ensure that is technique is an effective and reproducible treatment.

[What is the role of the correspondence of free PSA/total PSA in the staging of local prostate cancer? Series of 50 radical prostatectomy cases]. / Le rapport PSA libre/PSA total a-t-il sa place dans la stadification du cancer localisé de la prostate? A propos d'une série de 50 prostatectomies radicales.

OBJECTIVE: To refine the pretreatment staging of localized prostate cancers. MATERIAL AND METHOD: Prospective study on 50 total prostatectomy specimens from men with apparently prostate-confined adenocarcinoma. Preoperative assay of the free PSA/total PSA ratio and analysis of this ratio according to the presence of capsular effraction, capsular invasion and positive margins. RESULTS: Significant difference of this ratio according to the presence or absence of capsular effraction (13.2% versus 18.9%), capsular invasion (12.4% versus 17.5%) and positive margins (11.6% versus 16.3%). CONCLUSION: The free PSA/total PSA ratio can be useful for staging of prostate cancer, but this needs to be confirmed by a large-scale prospective study.

[Bladder hemangioma: a rare cause of hematuria. Apropos of a case. Review of the literature]. / L'hémangiome vésical: une cause rare d'hématurie. A propos d'une observation. Revue de la littérature.

The authors report a clinical case of multiple vesical haemangioma, a rare congenital benign vascular tumour essentially affecting children and young adults. These tumours may be solitary or multiple, and essentially spread to the bladder wall. They are sometimes associated with other sites, such as in the rare Klippel-Trenaunay-Weber syndrome. Usually presenting in the form of macroscopic haematuria, they are essentially diagnosed by endoscopy. Depending on the case, treatment consists of partial cystectomy or laser photocoagulation, rather than endoscopic resection, which is haemorrhagic and incomplete, or radiotherapy, which is insufficient. Selective arterial embolization is rarely used.

[Acute obstructive renal failure and scrotal complete hernia of the bladder. Apropos of a case, review of the literature]. / Insuffisance rénale aiguë obstructive et hernie scrotale complète de la vessie. A propos d'une observation, revue de la littérature.

Massive herniation of the bladder into the scrotum is uncommon and can have a deleterious effect on the upper urinary tract. We report a case where complete scrotal hernia of the bladder lead to obstructive renal failure due to torsion of the trigone. Most simple bladder hernias can be explained by a prostate or uretral obstacle. The mechanism in our patient with no known prostate or uretral disease was the passage of the bladder via a defective inguinal canal caused by excessive obesity. This type of massive hernia has been reported in Sumo boxers. The effect on the upper urinary tract may be related to a fold in the terminal ureter or more exceptionally in the trigone. Immediate treatment requires urine drainage above the obstacle and intensive care. After stabilization, the anatomic position of the excluded bladder is re-established with reconstruction of the inguinal area, usually with a prosthesis. Any obstacle below the bladder must be removed.