Malignant lymphomatoid granulomatosis infiltrating myocardium and producing sudden death.

The case of a 70 year old man suddenly deceased by myocardial lesions produced by a malignant pulmonary lymphomatoid granulomatosis is reported. The light microscopic pattern of the pulmonary, lymph node and myocardial lesions showed a polymorphous immunoblastic lymphoma.

[Sudden death from coronary thrombosis and myocardial infarct correlated with blood alcohol]. / Mortile subite prin tromboza coronara si infarct miocardic în corelatie cu alcoolemia.

The authors analyze the medicolegal files including 3,786 consecutive autopsies, of which 402 sudden coronary cardiac deaths. Autopsy was completed by histologic examination and toxicologic tests (alcoholemia). In the category of coronary cardiac sudden deaths there were 53 coronary thromboses (13.2%) and 36 recent myocardial infarction (8.95%). In 1,196 (31.6%) of 3,786 alcoholemia determinations the results were positive in 111 (27.6%), the difference between the two frequencies not being statistically significant (t less than 1.96). Alcoholemia was positive in 6 of 53 cases of coronary thromboses (11.3%, p less than 0.01), and in 36 cases of recent myocardial infarction alcoholemia was positive in 7 cases (19.5%; t less than 1.96).

[Cerebrovascular disease with a fatal outcome and the recent consumption of alcohol]. / Accidentele cerebrale vasculare cu evolutie fatala si consumul recent de alcool.

The authors have investigated 19 cases of nontraumatic cerebrovascular accidents with a fatal outcome from a total of 1,627 consecutive nonselected forensic autopsies. Alcohol concentration in the blood was determined in 15 cases of which 60% (9 subjects) tested positive. The median age of the group with positive alcohol blood tests was 50.4 +/- 6.2 years. The median age of the group with negative results was 51.7 +/- 5.4 years. In the group with positive tests 4 were chronic consumers of alcohol. As compared with 1,773 determinations of blood alcohol done in the general casuistics of forensic medicine it appears that the incidence of alcohol concentrations under 1 g/thousand is greater in subjects that died with cerebrovascular accidents. In the group of subjects with alcohol concentrations in the blood between 1 and 2 g/thousand, and over, reflecting an advanced degree of inebriation, there are no significant differences between the two lots. In the authors cases the haemorrhagic forms of nontraumatic cerebrovascular accidents were predominant. Ischaemic lesions were found in only two cases.