RESUMEN
Oxytropis is an important genus of the family Fabacea and subfamily Papillionoideae. About 99 Oxytropis species could be found in Mongolian land and Oxytropis pseudoglandulosa is endemic species of Mongolia. Pharmacological research of this plant showed anti-tumor, antisepticise, anti-inflammatory, hemostasis, neuroendocrine system effects and immune suppression activities. Phytochemical studies resulted to isolation of a lot of chemical compounds like alkaloids, flavonoids, saponins, lignans, volatile compounds and polysaccharides. Plants of the genus Oxytropis afford complex constituents, and many of them have been used in traditional folk medicine throughout the world. Phytochemical investigations led to the 127 components including flavonoids, alkaloids and saponins, etc. Some crude extracts and chemical constituents of the genus Oxytropis were found with significant biological and pharmacological activities. We worked on classification study of Oxytropis pseudoglandulosa. After the classification study, goal of this study is to develop agro technological cultivation method and cultivation Oxytropis pseudoglandulosa in experimental field instead of prepare raw material from wild herbals. We seem that both of wild and cultivated of Oxytropis pseidoglandulosa’s seed can be use as main raw material for this plant. In case of cultivation of this plant in the experimental field, the seed should be harvested from field in end of June and all vegetative development stage completed. Therefore the experimental field also has to equip with water canal and protect from wind and has a smooth surface. Key words Endemic, classification, aerial part, soil, seed, vegetative.
RESUMEN
BACKGROUND: Complete hydatidiform mole (CHM) is a high-risk pregnancy for gestational trophoblastic neoplasia (GTN). Patients with CHM have a 10-30% chance of trophoblastic sequelae. CHM includes androgenic homozygous (monospermic) and androgenic heterozygous (dispermic) moles. It is controversial whether the risk of GTN is higher with heterozygous than with homozygous CHM. A prospective cohort study was conducted to assess risk of GTN in homozygous and heterozygous CHM using short tandem repeat (STR) polymorphisms, and a meta-analysis of previous reports. METHODS: Twenty-eight consecutive molar pregnancies were evacuated and followed by regular hCG measurements to detect GTN. Persistent GTN was diagnosed according to the International Federation of Gynecology and Obstetrics 2000 system. Cytogenesis of the mole was determined by STR polymorphisms of molar tissue and parental blood. A meta-analysis of the GTN rate from previous reports was conducted using Mantel-Haenszel methods. RESULTS: Of 28 molar pregnancies, 24 were homozygous and three were heterozygous CHM. The remaining mole was diandric triploidy (a partial hydatidiform mole). Of the 24 homozygous CHMs, six (25%) cases developed GTN and received chemotherapy. Meanwhile, all three cases (100%) of heterozygous mole developed GTN and needed chemotherapy. The GTN risk was higher in heterozygous (P = 0.029, Fisher's exact test) than homozygous moles. A systematic review revealed only five previous reports (with more than 15 cytogenetically diagnosed cases), and the pooled relative risk of persistent GTN for heterozygous mole was not significant (odds ratio, 2.0; 95% confidence interval, 0.98-4.07). CONCLUSIONS: Heterozygous CHM had a higher risk for GTN than homozygous CHM.
