RESUMEN
The informative value of dipyridamole test, transesophageal cardiac pacing, bicycle ergometer and treadmill exercise tests were compared in 65 patients suspected for coronary heart disease and Functional Classes I-III angina pectoris. The sensitivity, specificity, positive and negative predictive values of the techniques alone and in various combinations were evaluated. The incoincidence of results from exercise tests was ascertained to be 40-48%. The significance of diagnosis increased with combined functional examination and reached the maximum when all the four tests were performed. The use of the sensitivity, specificity, and predictive value of the techniques in assessing the individual test results allows the optimal scope of studies to be determined on an individual basis in order to make or exclude the diagnosis of coronary heart disease.
Asunto(s)
Estimulación Cardíaca Artificial , Enfermedad Coronaria/diagnóstico , Dipiridamol , Prueba de Esfuerzo , Adulto , Estimulación Cardíaca Artificial/métodos , Esófago , Humanos , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Sensibilidad y EspecificidadRESUMEN
Structural and functional changes in the sciatic nerve induced by some drugs were studied using morphological and electrophysiological methods. It was stated that the application of this drug on the nerve causes different degenerating changes. Electrophysiological data, using the regeneration of action potential, proved the presence of structural changes in the nerve after application of mentioned drugs and showed partly preserved conduction of the nerve trunks.
Asunto(s)
Nervios Periféricos/efectos de los fármacos , Potenciales de Acción , Aminopirina/farmacología , Animales , Cloruro de Calcio/farmacología , Combinación de Medicamentos , Electrofisiología , Masculino , Degeneración Nerviosa , Regeneración Nerviosa , Nervios Periféricos/fisiología , Nervios Periféricos/ultraestructura , Fenilbutazona/farmacología , Prometazina/farmacología , Ratas , Nervio Ciático/efectos de los fármacosRESUMEN
The study into the nature and severity of clinical and electrocardiographic manifestations of paroxysms of atrial fibrillation in 213 patients with coronary heart disease identified the basic clinical and instrumental ECG signs (subjective attack tolerance, transient ECG changes, onset of left ventricular failure) that correspond to four stages of the natural history of paroxysmal atrial fibrillation. The use of the grades in clinical practice allows one to more definitely evaluate the status of patients, to correctly choose their management policy, and to define indications for hospitalization.
Asunto(s)
Fibrilación Atrial/diagnóstico , Enfermedad Coronaria/complicaciones , Anciano , Antiarrítmicos/administración & dosificación , Fibrilación Atrial/clasificación , Fibrilación Atrial/tratamiento farmacológico , Fibrilación Atrial/etiología , Electrocardiografía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Índice de Severidad de la EnfermedadRESUMEN
Comparison of pathohistological changes occurring in nerves after injection of agents into them with clinical observations showed that if the toxicity of the agent is sufficiently high to destroy the neuro-tissue barrier, or a less toxic agent is injected under the epineurium then degenerative changes develop in the nerve and their outcome depends on the degree of damage and the tactics of treatment.
Asunto(s)
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos , Inyecciones/efectos adversos , Traumatismos de los Nervios Periféricos , Adolescente , Adulto , Anciano , Animales , Modelos Animales de Enfermedad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Fibras Nerviosas/efectos de los fármacos , Fibras Nerviosas/patología , Nervios Periféricos/efectos de los fármacos , Nervios Periféricos/patología , RatasAsunto(s)
Sistema de Conducción Cardíaco/fisiopatología , Taquicardia/diagnóstico , Síndrome de Wolff-Parkinson-White/diagnóstico , Anciano , Estimulación Cardíaca Artificial/métodos , Diagnóstico Diferencial , Electrocardiografía , Ventrículos Cardíacos/fisiopatología , Humanos , Masculino , Taquicardia/etiología , Síndrome de Wolff-Parkinson-White/complicaciones , Síndrome de Wolff-Parkinson-White/fisiopatologíaAsunto(s)
Asfixia Neonatal/tratamiento farmacológico , Gluconato de Calcio/efectos adversos , Gluconatos/efectos adversos , Glucosa/efectos adversos , Isquemia/inducido químicamente , Nervio Ciático/irrigación sanguínea , Tiamina Pirofosfato/efectos adversos , Gluconato de Calcio/administración & dosificación , Femenino , Glucosa/administración & dosificación , Humanos , Lactante , Recién Nacido , Inyecciones Intraarteriales , Masculino , Tiamina Pirofosfato/administración & dosificación , Arterias Umbilicales/efectos de los fármacosRESUMEN
This paper discusses the potential application of a laser-endoscopic spectral analyzer in fibrolaryngoscopy for early detection of neoplasms (luminescence combined with spectrophotometry) as well as for examination of the laryngeal mucosa by measuring oxygenation and blood flow in microcirculation with the aid of spectrophotometry. The results of examinations of 35 patients have shown that the laser-endoscopic spectral analyzer can be used to perform premorphological rapid tests in cancer diagnosis and to assess the efficacy of therapeutic methods.