RESUMEN
Data on the frequency of detection of serological markers of hepatitis C and B viruses using enzyme immunoassay for examinations of blood donors in different regions of the country, of patients with hepatitis of obscure etiology and patients with hemophilia regularly receiving hemostatic therapy are presented. The rate of detection of antibody to hepatitis C (anti-HCV) in reserve donors varied from 2% (Baltic states) to 9.2% (Moldavia), that of the carrier state of HBsAg from 0.3% to 10.3%, respectively. Among patients with hepatitis of obscure etiology, anti-HCV was found in 9-18%. A higher rate of anti-HCV was found in donors with high levels of aminotransferases (18.75%) and in patients with hemophilia (77.6%). Epidemiological serological surveys of group incidence of hepatitis revealed a high portion of incidence of virus hepatitis C (from 50 to 90%).
Asunto(s)
Hepatitis B/diagnóstico , Hepatitis C/diagnóstico , Biomarcadores/sangre , Donantes de Sangre/estadística & datos numéricos , Portador Sano/diagnóstico , Portador Sano/epidemiología , Brotes de Enfermedades/estadística & datos numéricos , Hemofilia A/inmunología , Hepacivirus/inmunología , Anticuerpos Antihepatitis/sangre , Hepatitis B/epidemiología , Anticuerpos contra la Hepatitis B/sangre , Hepatitis C/epidemiología , Humanos , Incidencia , Estudios Retrospectivos , Estudios Seroepidemiológicos , Pruebas Serológicas , U.R.S.S./epidemiologíaRESUMEN
Altogether 65 patients with acute renal failure induced by blood transfusion were examined for the clinical and biochemical manifestations of hypoxia according to the determination of hemoglobin affinity for oxygen, of 2,3-DPH, ATP and creatine in red blood cells and for acid-base balance. It has been shown that both clinical and biochemical manifestations of hypoxia are most pronounced in oligoanuria and particularly during hemodialysis.