RESUMEN
Combined liver-pancreas transplantation is a relatively uncommon procedure. We report successful combined liver-pancreas transplantation in a patient with primary sclerosing cholangitis and insulin-dependent diabetes mellitus and review the literature on this topic.
Asunto(s)
Colangitis Esclerosante/cirugía , Diabetes Mellitus Tipo 1/cirugía , Trasplante de Hígado , Trasplante de Páncreas , Adulto , Anastomosis en-Y de Roux , Colangitis Esclerosante/complicaciones , Diabetes Mellitus Tipo 1/complicaciones , Humanos , Trasplante de Hígado/métodos , Masculino , Trasplante de Páncreas/métodosRESUMEN
BACKGROUND: Living donor liver transplantation has gained wide acceptance as an alternative for children with end-stage liver disease. The standard left lateral segment used in this operation does not provide adequate parenchymal mass to broaden its application to larger children or adults. METHODS: We report two cases of adult to adult living donor liver transplantation using a right hepatic lobe in patients with chronic liver disease. RESULTS: Both recipients experienced excellent initial graft function and have normal liver function 4 and 9 months postoperatively. Both donors are alive and well and returned to normal life 4 weeks postoperatively. CONCLUSIONS: Our initial experience suggests that this technique is a safe and reliable option for adults with chronic end-stage liver disease. A conservative application of this procedure in the adult population could significantly reduce the mortality on the adult waiting list.