RESUMEN
Two cases of Fanconis anemia (FA) are reported here. Case 1 presented with hypoplastic anemia and skeletal abnormality. Case 2, his older brother had stunted growth, investigations detected growth hormone deficiency and mild hematological derangement without other endocrine abnormality. FA was confirmed by positive chromosomal breakages studies in both cases.
RESUMEN
A subset of patients with lupus erythematosus develops erythema multiforme-like skin lesions with speckled pattern of antinuclear antibodies, positive rheumatoid factor, anti-Ro (SS-A), and anti-La antibodies (SS-B), which known as Rowell's syndrome. We report an adolescent boy presented with erythema multiforme-like skin lesions and pericardial effusion; he fulfilled criteria of both Rowell's syndrome and systemic lupus erythematosus (SLE). Such initial presentation of SLE is rarely reported in literature.
Asunto(s)
Eritema Multiforme/patología , Lupus Eritematoso Sistémico/patología , Derrame Pericárdico/patología , Piel/patología , Anticuerpos Antinucleares , Niño , Eritema Multiforme/inmunología , Humanos , Lupus Eritematoso Sistémico/inmunología , Masculino , Derrame Pericárdico/inmunología , SíndromeRESUMEN
A wasp sting rarely causes delayed / late onset hypersensitivity reaction. Although unknown, the mechanism of such a delayed hypersensitivity reaction is thought to be an immunologically mediated, type III hypersensitivity reaction with the deposition of immune complexes and activation of the complement system. We present here the case of a seven year-old girl with acute interstitial nephritis following multiple wasp stings. To the best of our knowledge, this is the first such report of delayed presentation in a child from India.
RESUMEN
TWO CLINICAL FORMS OF RABIES ARE RECOGNIZE: i) a furious form associated with classical signs of excitation or phobic symptoms, ii) Dumb rabies (paralytic rabies) characterized by progressive paralysis without an initial furious phase wherein distinction from Guillain-Barré Syndrome may be difficult. Paralytic rabies is more common in persons who have received postexposure vaccination. We report here the diagnostic dilemma of two cases of acute flaccid paralysis due to rabies.