Traumatic chylothorax in urbanized free-ranging black-tufted marmosets (Callithrix penicillata).

After fatal traumatic injuries, three urbanized free-ranging marmosets developed a milky white or pink-white thoracic alkaline effusion with high specific gravity, triglyceride levels, and predominance of small lymphocytes. Chylothorax is an uncommon thoracic fluid accumulation in animals and humans and has not been reported in free-ranging non-human primates.

Cerebral vascular hamartoma in a Campeiro Bulldog

Background: Vascular hamartomas (VH) are rare or simply underdiagnosed injuries in veterinary medicine and represent a non-neoplastic developmental anomaly disorganization and proliferation of endothelial tissue. VH occur in any region of the body, however in the brain present clinical relevance related with the potential for spontaneous bleeding, adjacent tissue compression and convulsive activity. The aim of these reports is to describe clinical, pathological and immunohistochemical features of a case of cerebrovascular hamartoma and highlight the diagnosis of these rare brain disorder in dogs. Case: A 10-year-old male dog, a Campeiro Bulldog breed presented convulsions episodes and died before an elective surgical procedure for eyelid nodule removal. Three red nodules were observed in the brain, one between the parietal lobe and the left occipital lobe (in the medium suprasylviam sulcus), the other in the caudal region of the corpus callosum and the third one in the cerebellar cortex. Central nervous system, eyelids and most organs and tissues samples were collected, fixed in 10% formaldehyde and processed for histopathological analysis. Histologically, in the eyelid was detected a sebaceous adenoma. The nervous system samples revealed well-differentiated sizes vascular structures with thin-walled and blood-filled, promoting compression of the brain. Normal neuropile was detected between the vascular structures substantiating cerebral vascular hamartoma diagnosis in the dog. Immunohistochemical assay was conducted with CD31 (monoclonal mouse antibody anti-CD31, Clone JC70A, Dako Corp.) and Von Willebrand factor (monoclonal mouse antibody anti-Von Willebrand factor, Clone F8/86, Dako Corp.) using the biotin–peroxidase–streptavidin method (PolyDetector Plus DAB–HRP, Bio SB) on CNS sections to confirm the vascular origin of the lining cells in the mass….(AU)

Cerebral vascular hamartoma in a Campeiro Bulldog

Background: Vascular hamartomas (VH) are rare or simply underdiagnosed injuries in veterinary medicine and represent a non-neoplastic developmental anomaly disorganization and proliferation of endothelial tissue. VH occur in any region of the body, however in the brain present clinical relevance related with the potential for spontaneous bleeding, adjacent tissue compression and convulsive activity. The aim of these reports is to describe clinical, pathological and immunohistochemical features of a case of cerebrovascular hamartoma and highlight the diagnosis of these rare brain disorder in dogs. Case: A 10-year-old male dog, a Campeiro Bulldog breed presented convulsions episodes and died before an elective surgical procedure for eyelid nodule removal. Three red nodules were observed in the brain, one between the parietal lobe and the left occipital lobe (in the medium suprasylviam sulcus), the other in the caudal region of the corpus callosum and the third one in the cerebellar cortex. Central nervous system, eyelids and most organs and tissues samples were collected, fixed in 10% formaldehyde and processed for histopathological analysis. Histologically, in the eyelid was detected a sebaceous adenoma. The nervous system samples revealed well-differentiated sizes vascular structures with thin-walled and blood-filled, promoting compression of the brain. Normal neuropile was detected between the vascular structures substantiating cerebral vascular hamartoma diagnosis in the dog. Immunohistochemical assay was conducted with CD31 (monoclonal mouse antibody anti-CD31, Clone JC70A, Dako Corp.) and Von Willebrand factor (monoclonal mouse antibody anti-Von Willebrand factor, Clone F8/86, Dako Corp.) using the biotin–peroxidase–streptavidin method (PolyDetector Plus DAB–HRP, Bio SB) on CNS sections to confirm the vascular origin of the lining cells in the mass….

Intoxicação espontânea por antibióticos ionóforos em equinos no Distrito Federal / Spontaneous intoxication by ionophortic antibiotics in equine on Distrito Federal

Quinze equinos em um haras na cidade satélite de Brazlândia-DF foram atendidos apresentando sinais clínicos caracterizados por quadro álgico abdominal, distúrbios locomotores, incoordenação e decúbito, após histórico de ingestão de um novo lote de ração. Três animais tiveram piora clínica e morreram. Os achados de necropsia consistiam em lesões em musculatura esquelética e miocárdio. O exame histológico revelou miopatia degenerativa, necrose segmentar e flocular. Correlacionando a etiopatogenia, sinais clínicos, achados necroscópicos e histopatológicos concluímos a possibilidade de surto por intoxicação de antiobióticos ionofóros.(AU)

Fifteen equines in a farm in the satellite city of Brazlândia/DF were treated with clinical signs characterized by abdominal pain, locomotor disorders, incoordination and decubitus, after a history of ingestion of a new feed batch. Three animals had clinical worsening and died. The necropsy findings consisted of skeletal muscle and myocardial lesions. Histological examination revealed degenerative myopathy, segmental and flocular necrosis. Correlating the etiopathogenesis, clinical signs, necroscopic and histopathological findings we conclude the possibility of an outbreakof intoxication of ionophore antiobiotics.(AU)

Intoxicação espontânea por antibióticos ionóforos em equinos no Distrito Federal / Spontaneous intoxication by ionophortic antibiotics in equine on Distrito Federal

Quinze equinos em um haras na cidade satélite de Brazlândia-DF foram atendidos apresentando sinais clínicos caracterizados por quadro álgico abdominal, distúrbios locomotores, incoordenação e decúbito, após histórico de ingestão de um novo lote de ração. Três animais tiveram piora clínica e morreram. Os achados de necropsia consistiam em lesões em musculatura esquelética e miocárdio. O exame histológico revelou miopatia degenerativa, necrose segmentar e flocular. Correlacionando a etiopatogenia, sinais clínicos, achados necroscópicos e histopatológicos concluímos a possibilidade de surto por intoxicação de antiobióticos ionofóros.

Fifteen equines in a farm in the satellite city of Brazlândia/DF were treated with clinical signs characterized by abdominal pain, locomotor disorders, incoordination and decubitus, after a history of ingestion of a new feed batch. Three animals had clinical worsening and died. The necropsy findings consisted of skeletal muscle and myocardial lesions. Histological examination revealed degenerative myopathy, segmental and flocular necrosis. Correlating the etiopathogenesis, clinical signs, necroscopic and histopathological findings we conclude the possibility of an outbreakof intoxication of ionophore antiobiotics.

Chronic equine proliferative pododermatitis / Pododermatite proliferativa crônica equina

Chronic equine proliferative pododermatitis (canker) is a chronic hypertrophic disease of the hoof, denoted by an excessive proliferation of the horn-producing tissues, which results from a dyskeratosis of the keratinocytes. It occurs mainly at the frog and sulci regions, but can sometimes also affect the heels, sole, bulbs or hoof wall. The etiology still remains unclear. Infectious agents such as anaerobic bacteria, viruses, spirochetes and fungi have been isolated from diseased tissues, but, moreover, an immune cause has been suggested, possibly related to a genetic predisposition. This report shows a case of a Brazilian Sport Horse, 10 years old, that had been affected on the right hindlimb for more than two years without a concise diagnosis. Success was achieved with the treatment consisting of oral prednisolone and topical Purple Mush®.

Pododermatite proliferativa crônica equina (cancro) é uma doença hipertrófica dos cascos, caracterizada por uma proliferação excessiva dos tecidos produtores de túbulos, o que resulta de uma disqueratose dos queratinócitos. Concentra-se principalmente na região da ranilha e seus sulcos, mas algumas vezes pode afetar também talões, bulbos, sola e parede do casco. A etiologia ainda não foi confirmada. Agentes infecciosos como bactérias anaeróbias, vírus, espiroquetas e fungos já foram isolados de tecidos afetados, mas cada vez mais uma hipótese imune vem sido discutida, possivelmente relacionada a uma predisposição genética. Este relato traz o caso de um Brasileiro de Hipismo, 10 anos, afetado no membro pélvico direito há mais de dois anos sem um diagnóstico conciso. O êxito foi obtido com o tratamento consistindo em Prednisolona oral e Purple Mush® tópico.

Chronic equine proliferative pododermatitis / Pododermatite proliferativa crônica equina

Chronic equine proliferative pododermatitis (canker) is a chronic hypertrophic disease of the hoof, denoted by an excessive proliferation of the horn-producing tissues, which results from a dyskeratosis of the keratinocytes. It occurs mainly at the frog and sulci regions, but can sometimes also affect the heels, sole, bulbs or hoof wall. The etiology still remains unclear. Infectious agents such as anaerobic bacteria, viruses, spirochetes and fungi have been isolated from diseased tissues, but, moreover, an immune cause has been suggested, possibly related to a genetic predisposition. This report shows a case of a Brazilian Sport Horse, 10 years old, that had been affected on the right hindlimb for more than two years without a concise diagnosis. Success was achieved with the treatment consisting of oral prednisolone and topical Purple Mush®.

Pododermatite proliferativa crônica equina (cancro) é uma doença hipertrófica dos cascos, caracterizada por uma proliferação excessiva dos tecidos produtores de túbulos, o que resulta de uma disqueratose dos queratinócitos. Concentra-se principalmente na região da ranilha e seus sulcos, mas algumas vezes pode afetar também talões, bulbos, sola e parede do casco. A etiologia ainda não foi confirmada. Agentes infecciosos como bactérias anaeróbias, vírus, espiroquetas e fungos já foram isolados de tecidos afetados, mas cada vez mais uma hipótese imune vem sido discutida, possivelmente relacionada a uma predisposição genética. Este relato traz o caso de um Brasileiro de Hipismo, 10 anos, afetado no membro pélvico direito há mais de dois anos sem um diagnóstico conciso. O êxito foi obtido com o tratamento consistindo em Prednisolona oral e Purple Mush® tópico.

Chronic equine proliferative pododermatitis: case report / Pododermatite proliferativa crônica equina: relato de caso

Chronic equine proliferative pododermatitis (canker) is a chronic hypertrophic disease of the hoof, denoted by an excessive proliferation of the horn-producing tissues, which results from a dyskeratosis of the keratinocytes. It occurs mainly at the frog and sulci regions, but can sometimes also affect the heels, sole, bulbs or hoof wall. The etiology still remains unclear. Infectious agents such as anaerobic bacteria, viruses, spirochetes and fungi have been isolated from diseased tissues, but, moreover, an immune cause has been suggested, possibly related to a genetic predisposition. This report shows a case of a Brazilian Sport Horse, 10 years old, that had been affected on the right hindlimb for more than two years without a concise diagnosis. Success was achieved with the treatment consisting of oral prednisolone and topical Purple Mush(AU)

Pododermatite proliferativa crônica equina (cancro) é uma doença hipertrófica dos cascos, caracterizada por uma proliferação excessiva dos tecidos produtores de túbulos, o que resulta de uma disqueratose dos queratinócitos. Concentra-se principalmente na região da ranilha e seus sulcos, mas algumas vezes pode afetar também talões, bulbos, sola e parede do casco. A etiologia ainda não foi confirmada. Agentes infecciosos como bactérias anaeróbias, vírus, espiroquetas e fungos já foram isolados de tecidos afetados, mas cada vez mais uma hipótese imune vem sido discutida, possivelmente relacionada a uma predisposição genética. Este relato traz o caso de um Brasileiro de Hipismo, 10 anos, afetado no membro pélvico direito há mais de dois anos sem um diagnóstico conciso. O êxito foi obtido com o tratamento consistindo em Prednisolona oral e Purple Mush tópico.(AU)

Chronic equine proliferative pododermatitis: case report / Pododermatite proliferativa crônica equina: relato de caso

Chronic equine proliferative pododermatitis (canker) is a chronic hypertrophic disease of the hoof, denoted by an excessive proliferation of the horn-producing tissues, which results from a dyskeratosis of the keratinocytes. It occurs mainly at the frog and sulci regions, but can sometimes also affect the heels, sole, bulbs or hoof wall. The etiology still remains unclear. Infectious agents such as anaerobic bacteria, viruses, spirochetes and fungi have been isolated from diseased tissues, but, moreover, an immune cause has been suggested, possibly related to a genetic predisposition. This report shows a case of a Brazilian Sport Horse, 10 years old, that had been affected on the right hindlimb for more than two years without a concise diagnosis. Success was achieved with the treatment consisting of oral prednisolone and topical Purple Mush(AU)

Pododermatite proliferativa crônica equina (cancro) é uma doença hipertrófica dos cascos, caracterizada por uma proliferação excessiva dos tecidos produtores de túbulos, o que resulta de uma disqueratose dos queratinócitos. Concentra-se principalmente na região da ranilha e seus sulcos, mas algumas vezes pode afetar também talões, bulbos, sola e parede do casco. A etiologia ainda não foi confirmada. Agentes infecciosos como bactérias anaeróbias, vírus, espiroquetas e fungos já foram isolados de tecidos afetados, mas cada vez mais uma hipótese imune vem sido discutida, possivelmente relacionada a uma predisposição genética. Este relato traz o caso de um Brasileiro de Hipismo, 10 anos, afetado no membro pélvico direito há mais de dois anos sem um diagnóstico conciso. O êxito foi obtido com o tratamento consistindo em Prednisolona oral e Purple Mush tópico.(AU)

Pathological alterations in dogs resulting from parasitism by Spirocerca Lupi

Background: Spirocercosis is considered to be an emerging pathological condition within veterinary medicine. The disease has worldwide distribution, although the greatest prevalence has been described in tropical and subtropical regions. The infection rate is affected by the interrelationships between the density of the dog population and intermediate hosts. The aim of this study was report the morphological and histopathological characteristics of natural infection by Spirocerca lupi in dogs from Distrito Federal, Brazil. Cases: Records were obtained from 10 dogs diagnosed with spirocercosis at the Pathology Sector, School of Veterinary Medicine, União Pioneira de Integração Social (UPIS), in Brasília, Federal District. For six animals, the diagnosis was confirmed through necropsy. Two dogs presented aortic rupture, thus resulting in hemothorax and consequent hypovolemic shock. Another animal presented gastric nodules, erratic migration to the lungs and renal and splenic infarction due to aortic thromboembolism. One dog presented neoplastic transformation of the esophageal granuloma to osteosarcoma. The age of the dogs ranged from one to eight years and the weight ranged from 15 to 40 kg. The clinical histories were similar: regurgitation (10/10), emesis (5/10), dysphagia (7/10), weight loss (10/10), weakness (3/10) and dyspnea (4/10). Esophageal nodules measured 1 to 5 cm in [...]

Pathological alterations in dogs resulting from parasitism by Spirocerca Lupi

Background: Spirocercosis is considered to be an emerging pathological condition within veterinary medicine. The disease has worldwide distribution, although the greatest prevalence has been described in tropical and subtropical regions. The infection rate is affected by the interrelationships between the density of the dog population and intermediate hosts. The aim of this study was report the morphological and histopathological characteristics of natural infection by Spirocerca lupi in dogs from Distrito Federal, Brazil. Cases: Records were obtained from 10 dogs diagnosed with spirocercosis at the Pathology Sector, School of Veterinary Medicine, União Pioneira de Integração Social (UPIS), in Brasília, Federal District. For six animals, the diagnosis was confirmed through necropsy. Two dogs presented aortic rupture, thus resulting in hemothorax and consequent hypovolemic shock. Another animal presented gastric nodules, erratic migration to the lungs and renal and splenic infarction due to aortic thromboembolism. One dog presented neoplastic transformation of the esophageal granuloma to osteosarcoma. The age of the dogs ranged from one to eight years and the weight ranged from 15 to 40 kg. The clinical histories were similar: regurgitation (10/10), emesis (5/10), dysphagia (7/10), weight loss (10/10), weakness (3/10) and dyspnea (4/10). Esophageal nodules measured 1 to 5 cm in [...](AU)