Characterization of the mechanical and biological properties of a new alumina scaffold.

PURPOSE: In this work, an alumina scaffold was produced through a new method to be used in a near future as a bone substitute. METHODS: In vitro and in vivo studies were performed in order to characterize the mechanical and biological properties of the scaffold. RESULTS: The results obtained showed that this scaffold has high mechanical resistance and a porous surface that allows human osteoblast cells to adhere and proliferate. The in vivo studies revealed no systemic reaction. CONCLUSIONS: The alumina scaffold produced herein has the mechanical and biological properties that are compatible with its application in bone therapy.