Effect of Myrtus communis L. Plant Extract as a Milk Supplement on the Performance, Selected Blood Parameters and Immune Response of Holstein Calves.

This research aimed to understand the effects of adding myrtle plant extract obtained from its leaves (MPEL) and roots (MPER) to the milk fed to suckling female Holstein calves, focusing on performance, reproduction, selected blood parameters and immune response. The 50 Holstein female calves, one week of age, were divided into five groups: one group received no plant extract (Control), while the others were supplemented with myrtle plant extracts at doses of 25 mL/day leaf extract (MPEL-25), 25 mL/day root extract (MPER-25), 50 mL/day leaf extract (MPEL-50) and 50 mL/day root extract (MPER-50) for each calf in each treatment group. The extracts were given along with the milk to the experimental groups for 60 days, and for an additional 12 days post-weaning. The results reveal that the feed consumption and live weights increased significantly. Significantly higher leukocyte counts were observed in the 50 mL/head × day myrtle groups, and a higher IgG concentration was also noted in the MPER-50 group compared to the other groups. The serum non-esterified fatty acid (NEFA) concentration significantly decreased in the MPEL-50 and MPER-50 groups, whereas the betahyrdoxy butyric acid (BHBA) concentration increased and the serum glucose concentration significantly decreased with myrtle supplementation. In conclusion, it was determined that the performance, immune system and negative energy balance compensation of female Holstein calves were positively affected by administering extracts obtained from the leaves and roots of the Myrtus communis L. plant at dose levels of 25 and 50 mL/head × day for 72 days, without causing any side effects.

Effect of a Dietary Essential Oil Blend in Dairy Cows during the Dry and Transition Period on Blood and Metabolic Parameters of Dams and Their Calves.

Cows face severe challenges of immunosuppression and negative energy balance during transition periods. The current study was designed to investigate the effects of essential oil blend supplementation in dairy cow's ration during dry periods on the health of the cow and calf. In the current study, 45 dry Holstein dairy cows were divided into three groups, each consisting of 15 animals. The control group was without any supplementation; the positive control group was only injected with 0.2 mg/kg levamisole (intramuscular) at 2 months before parturition and 1 month before parturition; and the treatment group was supplemented with 3 g/day for each cow essential oil blend mixed in total mixed ration (TMR). A mixed vaccine against E. coli, Rotavirus, and Coronavirus was administered to all cows before 42 days and after 21 days of calving. The day of the calving of the animal was accepted as day 0. Blood samples were collected from the coccygeal vein of all cows at -60, -45, -30, -15, -7, 0, 1 and 2 days, and the colostrum samples were taken on days 0, 1, and 2. Blood samples were also collected from the jugular vein (V. Jugularis) of the newborn calves on days 0, 1, and 2. The results of the hematological parameters revealed no difference in the total red blood cell count, hemoglobin amount, hematocrit, MCV, MCH, MCHC, RDW, PLT, MPV, and PCT values in both prenatal and postnatal blood of the cows (p > 0.05). In terms of immunological parameters, the total IgG level was significantly higher in the experimental group on the 7th day before birth compared to the other two groups, while the total leukocyte count, lymphocyte count, monocyte count and granulocyte counts were found to be lower after birth (p < 0005). Blood NEFA and BHBA levels were also lower in the experimental group compared to the other two groups (p < 0.005), and the blood glucose level was not different (p > 0.05). In calves, no difference was found between the groups in any of the parameters examined (p > 0.05). It is concluded that the dietary addition of an essential oil blend during the transition period enhanced the immune status and energy metabolism of cows without any effect on the health status of newborn calves.

Cross-Cultural Adaptation of the University of Wisconsin Running Injury and Recovery Index in Turkish Runners.

CONTEXT: The University of Wisconsin Running Injury and Recovery Index (UWRI) was developed to evaluate the key elements that runners use to self-assess their own running ability following common running-related injuries. The aim of this study was to translate and culturally adapt the UWRI and to evaluate the psychometric properties of its Turkish version (UWRI-Tr) in runners. DESIGN: Prospective cohort study. METHODS: The study included 129 runners. The UWRI-Tr, the Lower Extremity Functional Scale, the Oswestry Disability Index, the Hip Outcome Score, the International Knee Documentation Committee Subjective Knee Evaluation Form, and the Foot and Ankle Ability Measure were applied for the validation purposes. Internal consistency, reliability, construct validity, and discriminant validity of the UWRI-Tr were tested. RESULTS: The test-retest reliability of the UWRI-Tr was excellent with an intraclass correlation coefficient of .85 and a Cronbach α value of .84. There was a small to strong correlation among the UWRI-Tr and Lower Extremity Functional Scale (r = .278), Oswestry Disability Index (r = -.744), Hip Outcome Score (r = .684), The International Knee Documentation Committee Subjective Knee Evaluation Form (r = .758), and Foot and Ankle Ability Measure (r = .498 and .767), indicating that its construct validity was appropriate for use with Turkish runners. CONCLUSIONS: The UWRI-Tr was shown to be a valid and reliable tool to use in clinical and research settings as a sport-specific measurement tool.

Comparison of ankle force, mobility, flexibility, and plantar pressure values in athletes according to foot posture index.

Objectives: This study aims to compare ankle force, mobility, flexibility, and plantar pressure distribution of athletes according to foot posture index (FPI). Patients and methods: Between September 2016 and May 2018, a total of 70 volunteer male athletes (mean age: 21.1±2.3 years; range, 18 to 25 years) were included. The athletes were divided into three groups according to their FPI as follows: having supinated feet (Group 1, n=16), neutral/normal feet (Group 2, n=36), or pronated feet (Group 3, n=18). Ankle range of motion (ROM), muscle flexibility, ankle joint strength, and plantar pressure distribution were measured. Results: There were significant differences among the three groups in both right and left ankle dorsiflexion ROM (p=0.009 and p=0.003, respectively). Group 1 had significantly smaller dorsiflexion ROM than the other groups. Group 1 also showed significantly less flexibility in the gastrocnemius and soleus muscles than the other foot posture groups. Groups 2 and 3 exhibited significant differences in the maximum torque (p=0.018), maximum work (p=0.008), and total work (p=0.008) of the right plantar flexor muscles at 60°/sec angular velocity. Peak pressure measurements of the right foot were higher in Group 1, compared to Groups 2 and 3 (p<0.001). Conclusion: The results of this study may help to enhance athletic performance by providing a guide for designing training programs appropriate for athletes with different foot types to address their specific muscle flexibility and strength deficiencies.

Relationship between body composition, multiple repeated sprint ability and vertical jump performance in elite badminton players / Relación entre la composición corporal, la capacidad de realizar múltiples sprints repetidos y el rendimiento del salto vertical en jugadores de bádminton de élite

SUMMARY: The purpose of this study was to assess the correlation between the body composition, multiple repeated sprint ability (MRSAB) test, and vertical jump performance. Fifteen voluntary elite Turkish badminton players participated in the study. The MRSAB test consisted of 2 repetitions of 4 movements (4x3m) separated by 30 seconds of passive recovery. The best time (BT), meantime (MT), total time (TT), and fatigue index (FI) were measured. Body composition was evaluated through dual-energy X-ray absorptiometry (DEXA). Squat jump (SJ) test for explosive power and countermovement jump (CMJ) test for elastic power were used. The main findings were that there was a significant correlation between MRSAB MT and TT with lean body mass, lean arm mass, and trunk lean mass (kg) of male badminton players. However, no significant correlation was observed among MRSAB MT, BT, and TT with another total/regional body composition of female badminton players (p>0.05). Moreover, the results of male badminton players showed that there was a significant negative correlation between FI and percentage ofbody fat (%BF), percentage of leg fat (%LF), percentage of trunk fat (%TF), and trunk mass. In addition, there was a significant negative correlation between FI with %BF, body fat mass kg, percentage of arm fat (%AF), arm fat mass, and %LF of female badminton players. It was also found in the study that there was a significant correlation between SJ and %LF; CMJ and %BF, body fat mass kg, %AF, %LF and leg fat mass kg. However, no significant correlation was observed among CMJ and SJ with other total/regional body compositions of male badminton players (p>0,05). Finally, changes in body composition are important issues for the physical performance level of badminton players as regional excess body fat may cause deterioration, especially in repeated-sprint ability and jumping performance.

RESUMEN: El propósito de este estudio fue evaluar la correlación entre la composición corporal, la prueba de capacidad de sprint repetido (MRSAB) y el rendimiento del salto vertical. Quince jugadores voluntarios de bádminton turcos de élite participaron en el estudio. El test MRSAB consistió en 2 repeticiones de 4 movimientos (4x3m) separados por 30 segundos de recuperación pasiva. Se midieron el mejor tiempo (BT), el tiempo medio (MT), el tiempo total (TT) y el índice de fatiga (FI). La composición corporal se evaluó mediante absorciometría de rayos X de energía dual (DEXA). Se utilizó la prueba de salto desde la sentadilla (SJ) para la potencia explosiva y la prueba de salto con contramovimiento (CMJ) para la potencia elástica. Los principales hallazgos fueron una correlación significativa entre MRSAB MT y TT con la masa corporal magra, la masa magra del brazo y la masa magra del tronco (kg) de los jugadores de bádminton hombres. Sin embargo, no se observó una correlación significativa entre MRSAB MT, BT y TT con otra composición corporal total/regional de jugadoras de bádminton (p>0,05). Además, los resultados de los jugadores hombres de bádminton mostraron que había una correlación negativa significativa entre FI y el porcentaje de grasa corporal (% BF), porcentaje de grasa en las piernas (% LF), porcentaje de grasa en el tronco (% TF) y masa del tronco. Además, hubo una correlación negativa significativa entre FI con %GC, masa de grasa corporal en kg, porcentaje de grasa en el brazo (%AF), masa de grasa en el brazo y %LF de las jugadoras de bádminton. También se descubrió en el estudio que había una correlación significativa entre SJ y %LF; CMJ y %BF, masa grasa corporal kg, %AF, %LF y masa grasa de piernas kg. Sin embargo, no se observó una correlación significativa entre CMJ y SJ con otras composiciones corporales totales/regionales de los hombres jugadores de bádminton (p>0,05). Finalmente, los cambios en la composición corporal son cuestiones importantes para el nivel de rendimiento físico de los jugadores de bádminton, debido a que el exceso de grasa corporal regional, puede causar un deterioro, especialmente en la capacidad de repetir sprints y en el rendimiento de los saltos.

The Effects of Different Dietary Oil Sources on Broiler Chicken Bone Mineralization.

This study was designed to determine the effects of dietary hazelnut oil (HO) and sunflower oil (SO) on the mineral composition of chicken femur and tibia bones. A 40-day trial was initiated with 600 1-day-old Ross 308 chickens. Initially, the chickens were randomly divided into four main groups of 150 each according to the proportion of SO and HO supplementation in their diets: control SO (25 g/kg SO), LHO (25 g/kg HO), HHO (50 g/kg HO), and MO (50 g/kg blend of 25 g/kg SO + 25 g/kg HO). Each group was further divided into six subgroups of 25 chickens. At the end of the trial, four chickens from each of the six subgroups were randomly selected and slaughtered. Their right tibia and right femur bones were isolated and analyzed for macro (Ca, P, Mg) and trace (Fe, Cu, Mn, Zn, Cr, Co, and Se) minerals in addition to ether extract and ash. The results suggest that the diets' fat concentration and fatty acid composition significantly affected the Ca, P, Mg, Fe, Cu, Cr, and Se composition of tibia bones (p < 0.01). The ether extract and ash contents of the femur bones were increased in both HHO and MO groups (p < 0.05), while Fe and Cr compositions were lower in all femur bones, except those from SO chickens (p < 0.05). The Se content of femur bones in the LHO group was higher than the other treatment groups (p < 0.05). In conclusion, the amount of oil and fatty acid in the diet affected the accumulation of Ca, P, Mg, Fe, Cu, and Cr minerals in the tibia bone. Moreover, the amount of Cr and Fe was lower in the femur and tibia bones in the group that received the HO supplement and all groups in which the amount of oil fed was increased.

A Systematic Review and Meta-Analysis on the Longitudinal Effects of Unilateral Knee Extension Exercise on Muscle Strength.

The aim of the study was to investigate the time-dependent increase in the knee extensors' isometric strength as a response to voluntary, unilateral, isometric knee extension exercise (UIKEE). To do so, a systematic review was carried out to obtain data for a Bayesian longitudinal model-based meta-analysis (BLMBMA). For the systematic review, PubMed, Web of Science, SCOPUS, Chochrane Library were used as databases. The systematic review included only studies that reported on healthy, young individuals performing UIKEE. Studies utilizing a bilateral training protocol were excluded as the focus of this review lied on unilateral training. Out of the 3,870 studies, which were reviewed, 20 studies fulfilled the selected inclusion criteria. These 20 studies were included in the BLMBMA to investigate the time-dependent effects of UIKEE. If compared to the baseline strength of the trained limb, these data reveal that UKIEE can increase the isometric strength by up to 46%. A meta-analysis based on the last time-point of each available study was employed to support further investigations into UIKEE-induced strength increase. A sensitivity analysis showed that intensity of training (%MVC), fraction of male subjects and the average age of the subject had no significant influence on the strength gain. Convergence of BLMBMA revealed that the peak strength increase is reached after ~4 weeks of UIKEE training.

Comparison of ruminal digestibility of Origanum onites L. leaves in dairy buffalo and cows.

This experiment evaluated the ruminal digestibility of Turkish oregano leaves in dairy buffalo and cows. Ruminally cannulated, multiparous Brown Swiss cows (n = 3) and water buffalo (Bubalus bubalis; n = 3) were used in the experiment. The ad libitum basal diet was balanced to NRC requirements for a dry, nonpregnant multiparous dairy cow (680 kg) and consuming 12.8 kg of DM/day. Air-dried, ground, weighed oregano leaves were inserted in the rumen of all animals before the morning feeding within heat-sealed nylon bags (4 replicates per treatment and time point). After incubation (4, 8, 24, 48, and 72 h), dry matter (DM), crude protein (CP), aNDFom, and ADFom concentrations were determined and compared to initial leaf chemical composition. The means for in situ disappearance (ISD, %) of DM, aNDFom, and ADFom did not differ between the species, but ISD of CP was greater in buffalo than the cows (P = 0.05) after 72 h incubation. The lag time of kinetic degradation curves, the potentially degradable fraction (b), hourly degradation rate (c), and undegradable fraction were similar between species. The immediately degraded fraction (a) and effective digestibility (ED) of CP were greater in buffalo than the cows (P = 0.04), but the a fraction and ED of other nutrients showed no differences between the species. In conclusion, CP of oregano leaves are degraded more rapidly in the rumen of dairy buffalo than cows, primarily due to a large difference in the rapidly soluble CP fraction in the buffalo.

Supplementation of Cr Methionine During Dry Period of Dairy Cows and Its Effect on Some Production and Biochemical Parameters During Early Lactation and on Immunity of Their Offspring.

This study aimed to investigate the effect of dietary chromium methionine (Cr-Met) supplementation on the production and immunological parameters of dairy cows during the dry and postpartum period and their offspring. Forty-five Holstein transition cows were randomly assigned to experimental groups with control, positive control (levamisole-injected cows), and treatment groups (5 g dietary Cr-Met/day/cow). Production, immunological, and biochemical parameters were analyzed during the dry and postpartum period. Result revealed that in dry cows, monocyte count and serum glucose level significantly (p < 0.05) decrease in Cr-supplemented cows over control. Similarly, after parturition, the numbers of all immune cells (except monocytes) decreased significantly (p < 0.05); however, serum IgG, ALT, AST, glucose levels, and total leucocyte, neutrophil, and leucocyte count were increased significantly (p < 0.05) in Cr-supplemented cows over the control group. Days in milk (DIM) of treatment cows were significantly (p < 0.05) decreased over the control group; however, no significant (p > 0.05) differences were observed on milk production, colostrum, and IgG concentrations. As a conclusion, the supplementation of Cr had positive effects on immune cells of cows after parturition; however, serum biochemical parameters remained unaffected. Also, there were significant differences on the number of total leucocyte and neutrophil, on the activity of ALT at birthday, and on the number of total leucocyte at postpartum for calves.

The effects of hazelnut oil usage on live weight, carcass, rumen, some blood parameters and femur head ash in Akkaraman lambs.

This study was carried out to determine the effects of hazelnut oil supplementation in the diets on growth, carcass and blood parameters as well as rumen pH, protozoa quantity and femur head ash in Akkaraman lambs. Forty native Akkaraman lambs were used. The lambs were divided into two groups as treatment and control. The treatment group diet was supplemented with 3% hazelnut oil. The study was continued for 84days. The values regarding plasma malondialdehyde, cholesterol, triglyceride and antioxidant activity levels were found to be lower in the treatment group. In conclusion, supplementing 3% hazelnut oil in the diet of Akkaraman lambs had no detrimental effects on live weight, carcass and blood parameters, rumen microbial activity and femur ash. While the plasma glutathione and glucose levels increased, total cholesterol levels decreased. Considering the low level of malondialdehyde and high level of glutathione, it could be claimed that supplementation of hazelnut oil at 3% in diets plays a protective role against oxidative damage in the body. Therefore it could be used in sheep feeding.

Does sustained epinephrine release trigger a hypoxia-neovascularization cascade?

BACKGROUND: Recent data regarding the long-term local administration of epinephrine to soft tissues for the purpose of inducing prolonged vasoconstriction have yielded promising results. These studies postulated that long-term release of epinephrine by a microsphere/drug delivery system caused continuous vasoconstriction and subsequent vascular augmentation. The goal of this study was to test the hypothesis that epinephrine induces a hypoxia-neovascularization cascade and plays a primary role in vascular proliferation within soft tissues. METHODS: Thirty male New Zealand White rabbits were randomly grouped as follows: group I, control (n = 10); group II, saline-loaded microsphere/drug delivery system injection (n = 10); and group III, epinephrine-loaded microsphere/drug delivery system injection (n = 10). A 2 x 1-cm rectangle was marked on the dorsal surface of the left ear of each rabbit. No solutions were injected in the control group, whereas 1 ml of saline-loaded and epinephrine-loaded microspheres was injected into groups II and III, respectively. A laser Doppler device was used to measure tissue blood volume and tissue blood flow. RESULTS: Laser Doppler monitoring in tissue blood flow yielded a distinct difference between the epinephrine-loaded microsphere-injected group and the other two groups (p < 0.05). CONCLUSIONS: The ability of epinephrine-loaded microspheres to augment the vascular network in vivo is the result of sustained vasoconstriction with consequent tissue hypoxia and subsequent neovascularization. Data extracted from the present study, first, might be applied to improve hemostasis for operations typically plagued by serious intraoperative blood loss. Second, the ability to intentionally augment the vascularity of certain flaps before elevation should result in their increased survival. Radiation-injured tissues may also derive great benefit from this treatment.

Effects of probiotics: alone and in a mixture of Biosacc plus Zinc Bacitracin on the caecal microflora of Japanese quail.

The aim of this study was to investigate the effects of two commercially available probiotics, alone and in combination with an antibiotic, on the caecal flora of Japanese quail (Coturnix coturnix japonica) reared under unstressed conditions. Thirty-four 90-day-old Japanese quail were selected for this study. The birds were divided into four groups, two groups of nine birds and two groups of eight birds. The animals in these groups were given feed containing 0.5 kg per tonne of probiotics alone (Protexin or Biosacc), a mixture of probiotic plus antibiotic (Biosacc plus Zinc Bacitracin at 0.5 and 0.0525 ppm, respectively), and a group where no supplement was added to be used as controls. The total count of aerobic bacteria, lactobacilli, enterobacteriaceae, coliforms, enteroccoci, salmonellae, sulphite-reducing anaerobic bacteria (clostridia), and pH values in the caecal content of the birds were examined. No significant differences were detected among the four groups for pH values and bacterial number (p>0.05), except for sulphite-reducing anaerobic bacteria (p<0.001). These results suggest that the use of probiotics alone and/or a mixture of a probiotic plus antibiotic as a feed supplement does not have a major suppressing effect on the majority of bacterial groups in the caecal flora of mature, healthy Japanese quail reared in unstressed conditions.

Comparison of silver sulfadiazine 1%, mupirocin 2%, and fusidic acid 2% for topical antibacterial effect in methicillin-resistant staphylococci-infected, full-skin thickness rat burn wounds.

Silver sulfadiazine 1%, mupirocin 2%, and fusidic acid 2% were compared to assess the antibacterial effect of a once-daily application on experimental rat 15% full-skin thickness burn wounds seeded 24 hours earlier with a 10 standard strain of methicillin-resistant staphylococci. The quantitative counts of seeded organism in burn eschar and subjacent muscle were determined at postburn day 7, beside the cultures of blood and lung biopsies. All tested topical agents were equally effective against methicillin-resistant in reducing local burn wound bacterial count and preventing systemic infection.

[Reconstruction of the anomalous palatoglossal arch causing dysphagia: a case report]. / Yutma güçlügüne neden olan palatoglossal ark anomalisi ve cerrahi tedavisi.

Physical examination of a 20-year-old male patient suffering from dysphagia revealed an abnormally short and medially displaced palatoglossal arch. The mucosa was released by an inverse V incision, and the palatoglossal muscle was found to be located more laterally and cephalad than its usual insertion, attached to the posterior edge of the hard palate. The muscle was transposed medially and caudally to its normal localization on the soft palate, and the palatoglossal arch was reconstructed by closure of the mucosal incision in an inverse Y manner. The patient's complaint disappeared and no complications were observed in the postoperative period.

Free temporoparietal fascial flaps and full-thickness skin grafts in aesthetic restoration of the nose.

Free tissue transfers have been rapidly replacing distant flaps for use in nasal reconstruction. The temporoparietal fascial flap is a thin, broad, pliable, and well-vascularized flap. It can be used to drape over the cartilaginous and bony framework of the nasal skeleton and nourish the underlying primary cartilage grafts as well as the overlying full-thickness skin graft. The thin contour of the flap is aesthetically superior to thicker skin flaps and eliminates the need for secondary defatting or touch-up procedures. A large, single sheet of full-thickness skin graft, harvested from the supraclavicular region, can be applied over the fascial flap in the same session and provide a quite acceptable color match. The authors present a case whose alar margins and atrophic nasal skin were restored in one session by primary conchal cartilage grafts, a free temporoparietal fascial flap, and a full-thickness supraclavicular skin graft.