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Cancer Radiother ; 25(2): 169-174, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33436284

RESUMEN

Intramedullary spinal cord metastases (ISCM) is a rare, but devastating complication of malignant disease. Prognosis is poor, with an overall median survival (OS) of 4 months from the time of diagnosis. Yet, ISCMs are being increasingly diagnosed, related to advances and increased use of imaging and therapies that prolong survival in patients with cancer. Prompt and accurate diagnosis of ISCM is necessary for effective treatment, and magnetic resonance imaging (MRI) is the preferred imaging technique. The optimal management of these patients is controversial because of the multitude of clinical circumstances and the lack of controlled studies on the efficacy of the different therapeutic approaches. Increased awareness of this rare entity may lead to an earlier diagnosis at a stage when neurological deficits are reversible, and therefore, more effective palliation may be achieved. Therefore, we carried out this retrospective research of 3 observations of ISCM, associated with a detailed review of the literature describing the diagnostic, therapeutic and evolutionary characteristics of this special rare entity.


Asunto(s)
Adenocarcinoma/secundario , Carcinosarcoma/secundario , Enfermedades Raras/etiología , Neoplasias de la Médula Espinal/secundario , Adenocarcinoma/complicaciones , Adenocarcinoma/diagnóstico por imagen , Adenocarcinoma/terapia , Adulto , Neoplasias de la Mama/patología , Carcinosarcoma/complicaciones , Carcinosarcoma/diagnóstico por imagen , Carcinosarcoma/terapia , Detección Precoz del Cáncer , Resultado Fatal , Femenino , Humanos , Vértebras Lumbares , Neoplasias Pulmonares/patología , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Enfermedades Raras/diagnóstico por imagen , Enfermedades Raras/terapia , Estudios Retrospectivos , Neoplasias de la Médula Espinal/complicaciones , Neoplasias de la Médula Espinal/diagnóstico por imagen , Neoplasias de la Médula Espinal/terapia , Vértebras Torácicas
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