1.
Biopolymers
; 73(4): 451-6, 2004 Mar.
Artículo
en Inglés
| MEDLINE
| ID: mdl-14991662
RESUMEN
An inclusion complex of fenbufen with beta-cyclodextrin (beta-CD) in aqueous solution was characterized by (1)H-NMR spectroscopy. The [1:1] stoichiometry was determined and a stability constant of several 1000s (M(-1)) was calculated. The geometry of the inclusion complex was established based on MM(+) molecular mechanics calculations.