RESUMEN
On the basis of about one hundred and fifty cases, the authors study the effect of oral contraceptives on the gall-bladder. After having showed their results, they discuss the mechanism of the action of oral contraceptives on the gall-bladder, showing their favouring effect on gallstones and pointing out the delay in gall-bladder emptying induced by them.
Asunto(s)
Anticonceptivos Orales/efectos adversos , Enfermedades de la Vesícula Biliar/inducido químicamente , Animales , Bilis/efectos de los fármacos , Bilis/metabolismo , Colecistografía , Colelitiasis/inducido químicamente , Colelitiasis/diagnóstico , Anticonceptivos Orales/administración & dosificación , Perros , Femenino , Vesícula Biliar/efectos de los fármacos , Vesícula Biliar/patología , Enfermedades de la Vesícula Biliar/diagnóstico , Enfermedades de la Vesícula Biliar/terapia , Cobayas , Humanos , Embarazo , Progestinas/efectos adversos , ConejosRESUMEN
Based on a series of 159 cases of headache during oral contraception, the authors confirm the part plainly favouring and aggravating of oral contraceptives on headaches. They are dominated by the frequency of migraines and happen with predilection at the time of hormonal weaning. We deduct from this, that oral contraceptives generally aggravate or reveal a latent sensitivity to hormonal variations, especially clear with older women.
Asunto(s)
Anticonceptivos Orales/efectos adversos , Cefalea/inducido químicamente , Adulto , Factores de Edad , Estrógenos/efectos adversos , Femenino , Estudios de Seguimiento , Humanos , Menstruación , Trastornos Migrañosos/inducido químicamente , Progestinas/efectos adversos , Trastornos Psicofisiológicos/inducido químicamente , Factores de TiempoRESUMEN
PIP: Headaches experienced by 159 women during use of oral contraceptives for at least 1 year are characterized as migraine or tension headaches, and whether the headaches were related to dose or type of pill is examined. The 159 women accounted for 15% of a total of 1061 pill users: well-defined syndromes such as pituitary adenoma were eliminated. 47 of these women had headaches before, 31 of them worsened, and in 6 improved. Of 115 women with migraine, diagnosed by having at least 2 of 5 criteria for the disorder, 82 developed them during oral contraception. 12 of the 20 women with tension headaches had never had them before. 8 (5%) of the headaches were of indeterminate origin. In 50% headaches occurred during menses, or in 13% they were aggravated then. In 11 women the condition was improved by lowering progestagen dose. Generally migraines appeared or worsened within the 1st year of pill use, while tension headaches usually developed later. Younger women tolerated the pill better. 42 women stopped the pill because of headaches.^ieng