1.
Nanoscale
; 12(8): 4839-4845, 2020 Feb 27.
Artículo
en Inglés
| MEDLINE
| ID: mdl-32065596
RESUMEN
Despite the great interest in RNA therapeutics, the development of a successful gene delivery process is still a major challenge. We propose an efficient nucleic acid entrapment into the mesopores of biocompatible nanoscaled metal-organic frameworks. Their rapid cellular uptake together with RNA protection and release led to a relevant in vitro gene activity.