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Background: Posterior cervical foraminotomy and anterior cervical discectomy are routinely used operations to treat cervical brachialgia, although definitive evidence supporting superiority of either is lacking. Objective: The primary objective was to investigate whether or not posterior cervical foraminotomy is superior to anterior cervical discectomy in improving clinical outcome. Design: This was a Phase III, unblinded, prospective, United Kingdom multicentre, parallel-group, individually randomised controlled superiority trial comparing posterior cervical foraminotomy with anterior cervical discectomy. A rapid qualitative study was conducted during the close-down phase, involving remote semistructured interviews with trial participants and health-care professionals. Setting: National Health Service trusts. Participants: Patients with symptomatic unilateral cervical brachialgia for at least 6 weeks. Interventions: Participants were randomised to receive posterior cervical foraminotomy or anterior cervical discectomy. Allocation was not blinded to participants, medical staff or trial staff. Health-care use from providing the initial surgical intervention to hospital discharge was measured and valued using national cost data. Main outcome measures: The primary outcome measure was clinical outcome, as measured by patient-reported Neck Disability Index score 52 weeks post operation. Secondary outcome measures included complications, reoperations and restricted American Spinal Injury Association score over 6 weeks post operation, and patient-reported Eating Assessment Tool-10 items, Glasgow-Edinburgh Throat Scale, Voice Handicap Index-10 items, PainDETECT and Numerical Rating Scales for neck and upper-limb pain over 52 weeks post operation. Results: The target recruitment was 252 participants. Owing to slow accrual, the trial closed after randomising 23 participants from 11 hospitals. The qualitative substudy found that there was support and enthusiasm for the posterior cervical FORaminotomy Versus Anterior cervical Discectomy in the treatment of cervical brachialgia trial and randomised clinical trials in this area. However, clinical equipoise appears to have been an issue for sites and individual surgeons. Randomisation on the day of surgery and processes for screening and approaching participants were also crucial factors in some centres. The median Neck Disability Index scores at baseline (pre surgery) and at 52 weeks was 44.0 (interquartile range 36.0-62.0 weeks) and 25.3 weeks (interquartile range 20.0-42.0 weeks), respectively, in the posterior cervical foraminotomy group (n = 14), and 35.6 weeks (interquartile range 34.0-44.0 weeks) and 45.0 weeks (interquartile range 20.0-57.0 weeks), respectively, in the anterior cervical discectomy group (n = 9). Scores appeared to reduce (i.e. improve) in the posterior cervical foraminotomy group, but not in the anterior cervical discectomy group. The median Eating Assessment Tool-10 items score for swallowing was higher (worse) after anterior cervical discectomy (13.5) than after posterior cervical foraminotomy (0) on day 1, but not at other time points, whereas the median Glasgow-Edinburgh Throat Scale score for globus was higher (worse) after anterior cervical discectomy (15, 7, 6, 6, 2, 2.5) than after posterior cervical foraminotomy (3, 0, 0, 0.5, 0, 0) at all postoperative time points. Five postoperative complications occurred within 6 weeks of surgery, all after anterior cervical discectomy. Neck pain was more severe on day 1 following posterior cervical foraminotomy (Numerical Rating Scale - Neck Pain score 8.5) than at the same time point after anterior cervical discectomy (Numerical Rating Scale - Neck Pain score 7.0). The median health-care costs of providing initial surgical intervention were £2610 for posterior cervical foraminotomy and £4411 for anterior cervical discectomy. Conclusions: The data suggest that posterior cervical foraminotomy is associated with better outcomes, fewer complications and lower costs, but the trial recruited slowly and closed early. Consequently, the trial is underpowered and definitive conclusions cannot be drawn. Recruitment was impaired by lack of individual equipoise and by concern about randomising on the day of surgery. A large prospective multicentre trial comparing anterior cervical discectomy and posterior cervical foraminotomy in the treatment of cervical brachialgia is still required. Trial registration: This trial is registered as ISRCTN10133661. Funding: This project was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 27, No. 21. See the NIHR Journals Library website for further project information.
Cervical brachialgia is pain that starts in the neck and passes down into the arm. Although most people with cervical brachialgia recover quickly, in some patients pain persists, and in 15% of patients pain is so severe that they are unable to work. In the posterior cervical FORaminotomy Versus Anterior cervical Discectomy in the treatment of cervical brachialgia trial, we investigated two neck surgeries used to treat this problem: posterior cervical foraminotomy (surgery from the back of the neck) and anterior cervical discectomy (surgery from the front of the neck). This trial aimed to find out if one of them is better than the other at relieving pain and more cost-effective for the National Health Service. We assessed patients' quality of life 1 year after their surgery and how their pain changed over the course of the year. We also measured the number of complications patients had in the first 6 weeks after their operation. Recruitment was slow and so the trial was stopped early, after only 23 patients from 11 hospitals had been randomly allocated to the two surgery groups. We had planned to recruit 252 participants to the trial; the number of participants we were able to recruit in practice was too small to enable us to determine which surgery is better at relieving pain. To find out why the trial had struggled to recruit, we asked hospital staff and participants about their experiences. We found that hospital staff sometimes struggled to organise everything needed to randomise patients on the day of surgery. Some staff also found it difficult to randomise patients as they had an opinion on which surgery they thought the patient should receive. The data collected in the trial will still be useful to help design future research. Finding out which surgery is better at relieving pain remains important, and the data we have collected will support answering this question in future.
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Foraminotomía , Humanos , Medicina Estatal , Dolor de Cuello , Estudios Prospectivos , Discectomía , Análisis Costo-Beneficio , Calidad de VidaRESUMEN
Background: We describe a case of long-standing intracranial hypotension caused by an iatrogenic arachnoid diverticulum. This case illustrates two learning points. First, excessive CSF absorption may occur through an acquired arachnoid-epidural venous plexus at a dural defect. Second, a long-standing CSF leak may benefit from definitive surgical repair in the first instance. Case Description: A 55-year-old female, with known idiopathic intracranial hypertension, presented with disabling chronic low-pressure symptoms after having a lumboperitoneal shunt removed 5 years previously. MRI scan revealed a Chiari I malformation (CMI) and a small dural interruption at the L3/4 space. CT myelography confirmed the abnormality. Intraoperatively, a dural defect and arachnoid bleb with an overlying attachment of adipose tissue and a vessel were found. Postoperatively, the patient has marked resolution of her headaches and dizziness and is mobilizing independently. Conclusion: Excessive CSF absorption appears to have occurred through an acquired arachnoid-epidural venous plexus. A high index of suspicion for intracranial hypotension is required in patients with low pressure symptoms and a CMI.
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Objectives: To evaluate the impact of concomitant syringomyelia and self-reported complications on patient reported outcome measures in patients undergoing hindbrain decompression for a Chiari 1 malformation.Methods: Prospective data collection of 95 patients who underwent Foramen magnum decompression between March 2011 and March 2015. Outcome evaluation was performed using the Core Outcome Measure Index questionnaire for neck (COMI-neck) and Gestalt impression (to assess improvement of headaches). Patients were split into two cohorts, those with and those without syringomyelia. Both cohorts were compared in all domains of the COMI neck questionnaires, headache, and complications. Non-parametric data were analysed with Wilcoxon signed rank, Mann-Whitney U and Fisher exact tests. Parametric data were analysed with Student T-test. SPSS Software was used for analysis.Results: 79 patients returned 1 year follow-up COMI-neck questionnaires. Thirty three had concomitant syringomyelia and 46 had no syringomyelia present. There was no statistically significant difference in patient reported outcomes (COMI-neck index median 4.5 +/- 3.3 vs 4.2+/-3.2; p = .376) between the syrinx and non-syrinx cohorts. However postoperative neck pain (median 4 +/- 3.35 vs 1 +/- 3.17; p 0.041) and arm/shoulder pain scores (2 +/- 3.38 vs. 0+/- 2.628; p 0.049) were significantly lower in the non-syrinx cohort. In both cohorts 57% patients had an improvement in headache. 92% patients were 'satisfied' with treatment and 63% stated that the operation 'helped'. 54% patients in the syrinx and 59% in the non-syrinx cohort self-reported complications. There was no statistical difference in outcomes of the patients with and without self-reported complications (p = .121).Conclusions: This study demonstrates that the clinical effectiveness of FMD is lower and reported complications are higher when evaluated by patient reported outcome measures as opposed to surgeon reported complications. Patients with and without concomitant syringomyelia showed equal overall outcomes, although neck and arm pain was worse in syrinx patients.
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Malformación de Arnold-Chiari , Siringomielia , Malformación de Arnold-Chiari/complicaciones , Malformación de Arnold-Chiari/cirugía , Descompresión Quirúrgica , Humanos , Imagen por Resonancia Magnética , Medición de Resultados Informados por el Paciente , Estudios Prospectivos , Rombencéfalo , Siringomielia/complicaciones , Siringomielia/epidemiología , Siringomielia/cirugía , Resultado del TratamientoRESUMEN
The authors describe an unusual cause of ventriculoperitoneal shunt malfunction presenting as acute hydrocephalus.
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Migración de Cuerpo Extraño/complicaciones , Escroto , Derivación Ventriculoperitoneal/efectos adversos , Adulto , Catéteres de Permanencia/efectos adversos , Migración de Cuerpo Extraño/diagnóstico por imagen , Migración de Cuerpo Extraño/cirugía , Hernia Inguinal/etiología , Hernia Inguinal/cirugía , Humanos , Hidrocefalia/cirugía , Masculino , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/cirugía , Tomografía Computarizada por Rayos X , Resultado del TratamientoRESUMEN
Currarino syndrome (CS) is a congenital disorder characterized by partial sacral agenesis, anorectal malformation and a presacral mass. Only three cases of carcinoid transformation of the presacral mass have been described in the literature. We present a case of carcinoid transformation of presacral dermoid cyst in patient with Currarino syndrome.
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Canal Anal/anomalías , Tumor Carcinoide/patología , Quiste Dermoide/patología , Anomalías del Sistema Digestivo/patología , Recto/anomalías , Sacro/anomalías , Neoplasias de la Columna Vertebral/patología , Siringomielia/patología , Canal Anal/patología , Tumor Carcinoide/complicaciones , Transformación Celular Neoplásica , Quiste Dermoide/complicaciones , Anomalías del Sistema Digestivo/complicaciones , Humanos , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Recto/patología , Sacro/patología , Neoplasias de la Columna Vertebral/complicaciones , Siringomielia/complicacionesRESUMEN
BACKGROUND: Dorsal herniation of the spinal cord through the dura is an uncommon phenomenon and this is only the fifth reported case in the thoracolumbar spine, the first following surgery at the thoracolumbar junction. CASE: A 57-year-old male underwent marsupialisation of a benign intramedullary cyst at the T12-L1 level and subsequently returned with symptoms of dorsal column compromise. He was found to have a posterior herniation of the cord into a pseudomeningocele at the level of the previous surgery. CONCLUSION: The hernia was reduced surgically and the defect closed directly without the need for a dural patch leading to a full recovery. Posterior cord herniation, its possible aetiologies and management strategies are discussed.
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Quistes/cirugía , Meningocele/etiología , Procedimientos Neuroquirúrgicos/efectos adversos , Enfermedades de la Médula Espinal/cirugía , Humanos , Vértebras Lumbares , Masculino , Meningocele/cirugía , Persona de Mediana Edad , Vértebras TorácicasRESUMEN
OBJECTIVE: We aimed to study a group of patients presenting with symptomatic longstanding overt ventriculomegaly in adults (LOVA) requiring treatment (endoscopic third ventriculostomy), and to study their long term neuropsychological status and functionality. METHODS: Twenty patients were treated with endoscopic third ventriculostomy on presentation and were studied with neuropsychological assessments including the repeatable battery for the assessment of neuropsychological status and the hospital anxiety and depression scores. Pre- and post-operative MRI studies were used to assess the patency of the endoscopic third ventriculostomy (ETV) along with clinical outcome scores. RESULTS: A variety of presenting symptoms were experienced including headache (90%), worsening imbalance, attacks of loss of consciousness and cognitive decline. Mean age of patients was 52 years (range, 17-78) with mean head circumference of 60.9 cm. ETV was successful in controlling symptoms in 89% of patients with three patients requiring shunts (gravitational valves). There were no subdurals after surgery. All patients did universally badly in all aspects of the neuropsychological studies without showing any undue anxiety or depression. CONCLUSION: LOVA patients can decompensate at any time in their adult life with acute symptoms, which are generally well controlled with ETV and with few complications. Sadly, the long-term effects of carrying 'asymptomatic' or compensated hydrocephalus since childhood are of a significant cognitive cost to these patients.
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Hidrocefalia/cirugía , Trastornos Mentales/etiología , Enfermedades del Sistema Nervioso/etiología , Neuroendoscopía/métodos , Complicaciones Posoperatorias/etiología , Ventriculostomía/métodos , Adolescente , Adulto , Anciano , Femenino , Humanos , Hidrocefalia/psicología , Masculino , Persona de Mediana Edad , Neuroendoscopía/psicología , Pruebas Neuropsicológicas , Satisfacción del Paciente , Reoperación , Resultado del Tratamiento , Ventriculostomía/psicología , Adulto JovenRESUMEN
Protoplasmic astrocytoma is an extremely rare form of grade II low grade glioma which usually presents as a discrete mass lesion. We describe a 3-year-old female with diffuse protoplasmic astrocytoma with parenchymal involvement and leptomeningeal spread. This tumour proved extremely difficult to diagnose and followed a progressive course. Three superficial biopsies did not give the diagnosis and this was only confirmed 8 months from presentation from a larger fourth biopsy taken deeper from the cerebellum. To our knowledge this case represents the distinct presentation of protoplasmic astrocytoma presenting as extensive diffuse meningeal disease.
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Astrocitoma/patología , Neoplasias Cerebelosas/patología , Neoplasias Meníngeas/patología , Preescolar , Diagnóstico Tardío , Diagnóstico Diferencial , Epilepsia Tónico-Clónica/etiología , Femenino , Humanos , Imagen por Resonancia Magnética , Fotomicrografía , Tuberculosis Meníngea/diagnósticoRESUMEN
We report a case of an occipital arachnoid cyst in an infant, managed on the basis of changes in visually evoked potentials (VEPs). A significant asymmetry of VEP responses prompted neurosurgical intervention, which improved visual behavior and electrical response to both pattern and flash stimuli.
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Quistes Aracnoideos , Potenciales Evocados Visuales , Lóbulo Occipital/fisiopatología , Tomografía Computarizada por Rayos X , Quistes Aracnoideos/diagnóstico por imagen , Quistes Aracnoideos/fisiopatología , Quistes Aracnoideos/cirugía , Femenino , Humanos , Lactante , Lóbulo Occipital/diagnóstico por imagen , Lóbulo Occipital/cirugía , Tiempo de Reacción , Visión BinocularRESUMEN
OBJECTIVE: To evaluate the impact, on morbidity and mortality, of aggressive surgical management of subdural empyema of sinus origin in children. METHOD: The authors conducted a retrospective review of 20 children admitted between 2000-2007 to Alder Hay Children Hospital and The Walton centre for Neurology and Neurosurgery for subdural empyema secondary to sinus infection. Clinical presentation, duration of symptoms, radiological investigations, surgical treatment and post-operative outcome were evaluated. RESULTS: Outcome was favourable in 19 cases. In four cases, there were re-accumulation requiring surgical evacuation, four patients experienced post-operative seizures but were seizure-free at follow-up. There was only one mortality in the series. CONCLUSION: Subdural empyema secondary to sinus infection, although uncommon, it could be associated with a relative high morbidity and mortality rate. Early aggressive surgical and medical management with drainage of intracranial or sinus collections and antibiotics therapy lead to a low mortality or morbidity rate and good clinical outcome.
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Infecciones Bacterianas/complicaciones , Empiema Subdural/diagnóstico , Sinusitis/complicaciones , Adolescente , Antibacterianos/uso terapéutico , Niño , Drenaje/métodos , Empiema Subdural/etiología , Empiema Subdural/terapia , Estudios de Seguimiento , Humanos , Inyecciones Intravenosas , Imagen por Resonancia Magnética/métodos , Estudios Retrospectivos , Infecciones Estreptocócicas/complicaciones , Tomógrafos Computarizados por Rayos X , Resultado del TratamientoRESUMEN
Central nervous system maldevelopment can have different presentations in twins. We report on a case of different presentations of spina bifida occulta in monozygotic twins. The first twin presented at birth with a lipomyelomeningocele; a tethered cord was diagnosed in the second twin at 2 years of age. Neural tube defects (NTDs) are a group of common congenital malformations of the brain and spine generated during neurulation. The genetic basis of this process is still not well known. Whenever an NTD is diagnosed in one of a pair of twins, the other twin should also be evaluated for NTDs.
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Enfermedades en Gemelos , Espina Bífida Oculta , Niño , Preescolar , Femenino , Humanos , Lactante , Recién Nacido , Gemelos MonocigóticosRESUMEN
The authors present a case of a child with a tethered spinal cord associated with a myxopapillary ependymoma. This 16-month-old boy presented to the authors' institution with developmental delays in standing and walking. Magnetic resonance (MR) imaging demonstrated a fatty terminal filum and tethered cord. The child underwent surgical exploration of the spine with resection of the fatty filum tissue and release of the cord. Histological analysis of the fatty filum suggested the presence of a coexisting myxopapillary ependymoma. The child made a good recovery with no evidence of tumor recurrence after 4-years of follow-up with serial MR imaging. This unusual combination has not previously been reported in children, and to the authors' knowledge there is only one reported case in an adult. The likelihood of a common pathophysiological process in these conditions is also discussed.
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Cauda Equina , Ependimoma/patología , Lipoma/patología , Defectos del Tubo Neural/patología , Neoplasias del Sistema Nervioso Periférico/patología , Ependimoma/etiología , Ependimoma/cirugía , Humanos , Lactante , Lipoma/etiología , Lipoma/cirugía , Masculino , Defectos del Tubo Neural/etiología , Defectos del Tubo Neural/cirugía , Neoplasias del Sistema Nervioso Periférico/etiología , Neoplasias del Sistema Nervioso Periférico/cirugíaRESUMEN
OBJECT: Neuroendoscopy is increasingly used in neurosurgery. The authors report their evolving experience in the management of arachnoid cysts using endoscopic techniques and, more recently, the use of these techniques in combination with neuronavigation systems. The aim of this study was to assess the efficacy of this approach and the factors influencing the final outcome of treatment. METHODS: The authors reviewed 39 cases in which patients were treated endoscopically for intracranial arachnoid cysts over a period of 8 years. The indications and techniques used were reviewed and the surgical outcomes assessed. There was no death or significant morbidity associated with the procedure. Thirty-six patients had resolution or improvement of symptoms and only three required insertion of a shunt. CONCLUSIONS: The treatment of arachnoid cysts has been revolutionized by the introduction of endoscopic techniques. The authors conclude on the basis of their experience that in most cases the combination of neuroendoscopy and frameless navigation represents a safe and reliable modality for treating this benign intracranial entity with minimal surgical trauma. The specific approach should be based on the individual characteristics of each cyst and the surgeon's experience.
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Quistes Aracnoideos/cirugía , Endoscopía , Neuronavegación , Procedimientos Neuroquirúrgicos/métodos , Adolescente , Adulto , Anciano , Quistes Aracnoideos/diagnóstico , Niño , Preescolar , Fosa Craneal Posterior , Femenino , Humanos , Lactante , Recién Nacido , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Procedimientos Quirúrgicos Mínimamente Invasivos , Silla Turca , Techo del Mesencéfalo , Resultado del TratamientoRESUMEN
The aim of this study was to determine predictors of functional outcome and survival in a retrospective cohort of spinal cord ependymomas treated at a single institution. Twenty-six patients who underwent treatment of spinal cord ependymoma at a single institution were retrospectively analysed. The clinicopathological features were reviewed and correlated with functional outcome (measured using the Frankel grade), recurrence (clinical or radiological), progression-free survival (PFS) and overall survival (OS). Seventy-nine percent of patients with complete excision had maintained or improved functional outcome, compared to 75% in the incomplete resection plus radiotherapy group. Patients with a good pre-operative Frankel grade tended to maintain their functional status, though this did not reach statistical significance (Fisher's Exact test, P = 0.090). Univariate analysis revealed that longer symptom duration prior to treatment was associated with poorer functional outcome (P = 0.006). Extent of resection and the use of adjuvant radiotherapy did not influence PFS or OS; however, early diagnosis and treatment are paramount in the management of spinal ependymoma if a good functional outcome is to be achieved.
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Ependimoma/radioterapia , Ependimoma/cirugía , Neoplasias de la Médula Espinal/radioterapia , Neoplasias de la Médula Espinal/cirugía , Adulto , Anciano , Estudios de Cohortes , Terapia Combinada , Interpretación Estadística de Datos , Supervivencia sin Enfermedad , Ependimoma/diagnóstico , Humanos , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Pronóstico , Radioterapia Adyuvante , Estudios Retrospectivos , Neoplasias de la Médula Espinal/diagnóstico , Resultado del TratamientoRESUMEN
OBJECTIVE: The objective was to study the injuries from the deployment of military parachutes when parachuting with foreign armies. METHODS: The number and nature of injuries sustained while military parachuting with domestic and foreign parachute systems and techniques was compared. RESULTS: Of a total of 370 parachutists, 41 (11.1%) suffered minor injuries following two descents on the British parachute, 20 (5.4%) of these were classified as riser injuries. Thirty-eight (25.9%) of 147 British parachutists sustained riser injuries following two descents with the French parachute. Thirty-four (89.5%) of these injuries were minor posterior-auricular bruises and abrasions not requiring treatment. Four (10.5%) were extensive posterior-auricular abrasions that required treatment. Two soldiers (5.3%) suffered lacerations of the attachment of the pinna to the head. There were no riser injuries and no other injuries when the soldiers parachuted with their own countries parachutes in the proceeding two descents. CONCLUSION: Failure to adhere to drills led to injuries with foreign parachute systems.
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Accidentes de Aviación/estadística & datos numéricos , Accidentes de Trabajo/estadística & datos numéricos , Aviación/instrumentación , Medicina Militar/estadística & datos numéricos , Personal Militar/estadística & datos numéricos , Heridas y Lesiones/epidemiología , Diseño de Equipo , Seguridad de Equipos , Francia/epidemiología , Humanos , Internacionalidad , Personal Militar/educación , Postura , Reino Unido/epidemiología , Heridas y Lesiones/etiologíaAsunto(s)
Ependimoma/diagnóstico , Mielitis Transversa/diagnóstico , Neoplasias de la Médula Espinal/diagnóstico , Adulto , Biopsia , Errores Diagnósticos , Humanos , Imagen por Resonancia Magnética , Masculino , Metilprednisolona/administración & dosificación , Bandas Oligoclonales/líquido cefalorraquídeo , Médula Espinal/patología , Resultado del TratamientoRESUMEN
This 80-year-old woman presented with acute breathing difficulty during neck flexion when cyanosis also developed. The only potential causes were detected on cervical magnetic resonance imaging: two large anterior cervical osteophytes compressing the retropharyngeal space. Excision of these osteophytes resulted in resolution of the symptoms.
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Obstrucción de las Vías Aéreas/etiología , Vértebras Cervicales , Laringismo/etiología , Osteofitosis Vertebral/complicaciones , Anciano de 80 o más Años , Obstrucción de las Vías Aéreas/diagnóstico , Obstrucción de las Vías Aéreas/cirugía , Vértebras Cervicales/patología , Vértebras Cervicales/cirugía , Femenino , Movimientos de la Cabeza/fisiología , Humanos , Laringismo/diagnóstico , Laringismo/cirugía , Imagen por Resonancia Magnética , Osteofitosis Vertebral/diagnóstico , Osteofitosis Vertebral/cirugíaRESUMEN
INTRODUCTION: Iatrogenic intracranial aneurysms are rare in children. CASE REPORT: A 15-year-old girl presented in coma with a fixed dilated left pupil six weeks following removal of a long-standing left-sided ventriculoperitoneal shunt. Computed tomography (CT) and cerebral angiography revealed a left temporoparietal intracerebral haemorrhage with a fusiform distal middle cerebral artery aneurysm. The patient underwent image-guided localisation of the aneurysm to enable evacuation of the haemorrhage and resection of the fusiform aneurysm. CONCLUSION: A high index of suspicion is required for diagnosis and early treatment to prevent unnecessary morbidity and mortality.
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Aneurisma Intracraneal/etiología , Derivación Ventriculoperitoneal/efectos adversos , Adolescente , Angiografía Cerebral/métodos , Femenino , Humanos , Aneurisma Intracraneal/patología , Tomografía Computarizada por Rayos X/métodosRESUMEN
BACKGROUND/PURPOSE: The time limit for the use of external ventricular drains (EVDs) has always been controversial. The purpose of this study is to find out if there is a time limit with regard to infection of EVDs and their duration of use in children. METHODS: The records of 28 patients who had a total of 46 EVDs over a 4-year period at the Regional Paediatric Neurosurgical Centre at the Royal Liverpool Children's Hospital, Alder Hey, Liverpool, UK, were retrieved. The cerebrospinal fluid (CSF) white cell counts, CSF Gram stains and the CSF culture results were analysed. CONCLUSION: There is no time limit for EVDs in children. They can be left as long as clinically indicated provided strict protocols are followed in the handling of the set.