Diseases with neurological manifestations diagnosed in cattle in the hospital routine: a retrospective epidemiological study (2009-2019) / Enfermidades com manifestações neurológicas diagnosticadas em bovinos na rotina hospitalar: estudo epidemiológico retrospectivo (2009-2019)

Abstract Neurological disorders in cattle comprise a group of economically relevant diseases with high occurrence and mortality. In this way, the objective was to carry out an epidemiological study of the diseases with neurological manifestations in cattle admitted (alive or dead) to the Garanhuns Bovine Clinic/Federal Rural University of Pernambuco (CBG/UFRPE) from January 2009 to December 2019. Epidemiological information was collected from the clinical records regarding the age group, rearing system, time of year, and area of origin of the animals. The diseases were grouped into categories according to their origin: toxic or toxi-infectious, viral, traumatic/physical, parasitic, metabolic degenerative, bacterial, neoplastic, and others. A total of 6103 cattle were treated during the study period, of which 604 (10.1%) were diagnosed with diseases that had neurological manifestations. Of these, 331 cases were of single occurrence, and 231 cases occurred as outbreaks in the herd. Death was the outcome in almost 80% of the cases (465/596). The frequencies of the different categories were toxic or toxi-infectious (25.2%), viral (21.5%), traumatic/physical (13.6%), parasitic (9.8%), metabolic (9.3%), degenerative (2.3%), bacterial (2.2%), neoplastic (1.2%), and others (1.2%). It was found that almost half of the animals were older than 24 months (229/475), almost 80% were females, more than 60% were submitted to a semi-intensive to intensive rearing system, and the occurrence of disease was higher during the dry period of the year (363/614). The three most frequent neurological diseases in this study were rabies, trauma, and botulism.

Resumo Os distúrbios neurológicos em bovinos abrangem um grupo de enfermidades economicamente relevantes de elevada ocorrência e mortalidade. Desta forma, objetivou-se realizar um estudo epidemiológico das enfermidades que cursaram com manifestações neurológicas que deram entrada (vivos ou mortos) na Clínica de Bovinos de Garanhuns/Universidade Federal Rural de Pernambuco no período de janeiro de 2009 a dezembro de 2019. Nos prontuários clínicos, foram coletadas informaçõe epidemiológicas referentes ao sexo; a faixa etária; ao sistema de criação, época do ano e a área de procedência dos animais. As doenças foram agrupadas em categorias de acordo com sua origem: tóxica ou toxi-infecciosa, viral, traumática, parasitária, degenerativa, metabólica, bacteriana, neoplásica e outras. Um total de 6103 bovinos foram atendidos no período estudado, dos quais 604 (10,1 %) foram diagnosticados com enfermidades que cursaram com manifestações neurológicas. Destes, 331 casos foram de ocorrência individual, 231 casos cursaram como surtos no rebanho. Quase 80% dos casos (465/596) teve o óbito como desfecho. As frequências das distintas categoria foram tóxica ou toxi-infecciosa (25,2%), viral (21,5%), traumática/física (13,6%), parasitária (9,8%), metabólica (9,3%, degenerativa (2,3%), bacteriana (2,2%), neoplásica (1,2%), outras (1,2%). Verificou-se que quase metade dos animais apresentavam idade superior a 24 meses (229/475), quase 80% eram fêmeas, mais de 60% eram submetidos a um sistema de criação de semi-intensivo a intensivo e a ocorrência foi maior durante o período seco do ano (363/614). As três enfermidades com manifestações neurológicas de maior ocorrência neste estudo foram a raiva, os traumatismos e o botulismo.

Epidemiological and anatomopathological findings of type 1 and 2 abomasum ulcers in cattle with different comorbidities / Achados epidemiológicos e anatomopatológicos de úlceras do abomaso tipo 1 e 2 em bovinos com diferentes comorbidades primárias

This study aimed to investigate the epidemiological and pathological findings of type 1 and 2 abomasal ulcers in cattle with different primary comorbidities. A total of 201 animals; 40/201 (20%) were young cattle under the age of two years and 161/201 (80%) were adult cattle over the age of two years, which were hospitalized for clinical care 152/201 (75,62%), 19/201 (9,45%) obstetric care, 17/201 (8,46%) surgical care and 13/201 (6,47%) for anatomopathological diagnosis, being euthanized or had natural death. The diagnosis of ulcers was based on the result of the post-mortem examination (macroscopic and histopathological analysis). Histopathological examination was performed on 201 fragments of ulcers and classified as type 1 or type 2. Of these, 193/201 (96.01%) corresponded to type 1 ulcers, of which 12/193 (5.97%) corresponded to subtype 1a lesions, 101/193 (50.25%) to subtype 1b, 77/ 193 (38.31%) to subtype 1c, 03/193 (1.49%) to subtype 1d, while 08/201 (3.98%) were type 2 ulcers. The ulcers were characterized by a focal, focally extensive, multifocal or diffuse inflammatory process, mainly by mononuclear cells. Abomasitis associated with ulcerated mucosa was found in 160/201 (79.60%). In 26/201 (12.93%) the abomasitis had diffuse foci of multifocal lymphocytic proliferation by atypical lymphocytes. Digestive and reproductive comorbidities were seen more frequently in cattle with type 1 or type 2 ulcers. The Subtype 1b focal ulcers and subtype 1a and 1b multifocal ulcers were more prevalent. In addition to the presence of comorbidities, most cases occur in the dry period, associated with feeding with higher amounts of concentrates and silages.(AU)

Objetivou-se estudar os achados epidemiológico e anatomopatológico de úlceras do abomaso tipo 1 e 2 em bovinos com diferentes comorbidades primárias. Um total de 201 animais; 40/201 (20%) eram bovinos jovens com idade inferior a dois anos e 161/201 (80%) eram bovinos adultos com idade superior a dois anos, os quais foram internados para atendimento clínico 152/201 (75,62%), 19/201 (9,45%) obstétrico, 17/201 (8,46%) para atendimento clínico-cirúrgico e 13/201 (6,47%) para diagnóstico anatomopatológico, sendo eutanasiados ou tiveram morte natural. O diagnóstico das úlceras foi baseado no exame post-mortem (análise macroscópica e histopatológica). O exame histopatológico foi realizado em 201 fragmentos de úlceras e classificado como tipo 1 ou do tipo 2. Destes, 193/201 (96,01%) corresponderam a úlceras tipo 1, das quais, 12/193 (5,97%) corresponderam a lesões subtipo 1a, 101/193 (50,25%) a subtipo 1b, 77/193 (38,31%) a subtipo 1c, 03/193 (1,49%) ao subtipo 1d, enquanto 08/201 (3,98%) foram úlceras tipo 2. As úlceras foram caracterizadas por processo inflamatório focal, focalmente extenso, multifocais ou difusos, principalmente por células mononucleares. Abomasite associada à mucosa ulcerada foi encontrada em 160/201 (79,60%). Em 26/201 (12,93%) a abomasite apresentava focos difusos de proliferação linfocítica multifocal por linfócitos atípicos. As comorbidades digestivas e reprodutivas foram observadas com maior frequência em bovinos com úlceras tipo 1 ou tipo 2. As úlceras focais subtipo 1b e úlceras multifocais subtipo 1a e 1b foram mais prevalentes. Além da presença de comorbidades, a maioria dos casos ocorrerem no período seco, associados à alimentação com maiores aportes de concentrados e silagens.(AU)

Vagal indigestion in cattle: a retrospective study / Indigestão vagal em bovinos: estudo retrospectivo

This study aimed to carry out a retrospective study of vagal indigestion cases diagnosed in cattle admitted at the Garanhuns Bovine Clinic, Federal Rural University of Pernambuco campus. This syndrome, caused by dysfunctions of the vagus nerve and characterized by motility disorders of the pre-stomachs and abomasum, represented 5.5% (70/1279) of digestive cases diagnosed in a period of 10 years and had an unfavorable prognosis in 78.3% of cases. Type II vagal indigestion was the most prevalent, accounting for 40% of cases, followed by type I (24.3%) and types III and IV, which accounted for 18.6% and 10.0% of cases, respectively. Vagal indigestion in 67.1% (47/70) of cases occurred as a result of other illnesses, such as traumatic reticuloperitonitis (27.7%), lung diseases (12.8%), gastric impaction (10.6%), abomasal ulcer (10.6%), lymphosarcoma (6.4%), and liver abscesses (6.4%). Motor changes in the gastrointestinal tract, such as hypomotility, abdominal distension, and bloat, as well as their consequences, were the most frequent clinical signs. Laboratory, ultrasonographic, and anatomopathological alterations mainly originate from the primary illnesses present in each case. The approach of this disease is essential due to its clinical and economic importance for livestock to expand the knowledge of its etiopathogenesis, thus contributing to a more accurate diagnosis by veterinarians working in the field of internal medicine for cattle.

Objetivou-se realizar um estudo retrospectivo dos casos de indigestão vagal diagnosticados em bovinos atendidos na Clínica de Bovinos de Garanhuns, campus da Universidade Federal Rural de Pernambuco. Essa síndrome, causada por disfunções do nervo vago e caracterizada por transtornos de motilidade dos pré-estômagos e abomaso, representou 5,5% (70/1279) dos casos digestivos diagnosticados num período de 10 anos e apresentou prognóstico desfavorável em 78,3% dos casos. A indigestão vagal tipo II foi a mais prevalente, representando 40% dos casos, seguida do tipo I (24,3%) e dos tipos III e IV, que corresponderam a 18,6% e 10,0%, respectivamente. Em 67,1% (47/70) dos casos, a indigestão vagal ocorreu em consequência de outras enfermidades, tais como reticuloperitonite traumática (27,7%), doenças pulmonares (12,8%), compactação gástrica (10,6%), úlcera de abomaso (10,6%), linfossarcoma (6,4%) e abscessos hepáticos (6,4%). As alterações motoras do trato gastrointestinal, tais como hipomotilidade, distensão abdominal e timpania, assim como suas consequências foram os sinais clínicos mais frequentes. As alterações laboratoriais, de imagem e anatomopatológicas são oriundas principalmente das enfermidades primárias presentes em cada caso. Devido sua importância clínica e econômica para a bovinocultura, é primordial a abordagem dessa enfermidade, visando ampliar o conhecimento da sua etiopatogenia contribuindo dessa forma para um diagnóstico mais preciso pelos médicos veterinários atuantes na área de medicina interna de bovinos.

Occurrence of foot diseases in cattle attended at the Clínica de Bovinos de Garanhuns: Epidemiological, clinical, therapeutic and economic aspects / Ocorrência de afecções podais em bovinos atendidos pela Clínica de Bovinos de Garanhuns: aspectos epidemiológicos, clínicos, terapêuticos e econômicos

The objective was to study the occurrence of foot disorders in cattle treated at the Clínica de Bovinos de Garanhuns, campus of the Universidade Federal Rural de Pernambuco from 1999 to 2021. A retrospective study of the medical records was carried out, with a total of 334 cases, in which 613 lesions were diagnosed. A frequency distribution, with simple mean and standard deviation was performed to evaluate the data. Interdigital dermatitis was more frequent in 12.4% (76/613), double sole in 9.79% (60/613), chronic laminitis in 8.81% (54/613), sole ulcer in 7.83% (48 /613), and interdigital hyperplasia in 7.24% (45/613). Laminitis and its consequences accounted for 45% of the total injuries identified, followed by 36% of injuries of secondary or uncertain cause, and 19% from infectious diseases. The distribution of lesions between the limbs was 68% in the pelvic and 32% in the thoracic limbs. Females, raised in a semi-intensive system, Holstein, with a body score of III, and large size were more affected. Lameness was present in 78% (260/334), while 10% (33/334) did not present lameness. The case fatality and recovery rates were 9% (31/334) and 73% (243/334), respectively. In total, 51% of cases occurred in the rainy season and 49% in the dry season. The main cities of origin were Bom Conselho 22.75% (76/334), Garanhuns 18.86% (63/334), and Brejão 12.57% (42/334). The estimated cost of treatment was US$ 150.13/case. Diseases are probably directly linked to management failure on the property due to the nature of the diagnosed diseases, in addition to the significant cost of the treatment of these animals, with the need for prophylactic measures in order to avoid the economic losses associated with foot diseases.

Objetivou-se estudar a ocorrência das afecções podais em bovinos atendidos na Clínica de Bovinos de Garanhuns, Campus da Universidade Federal Rural de Pernambuco, no intervalo de 1999 a 2021. Realizou-se estudo retrospectivo dos prontuários, com total 334 casos, dos quais foram diagnosticadas 613 lesões digitais. Foi realizada a distribuição de frequência, média simples e desvio padrão para avaliação dos dados. A dermatite interdigital foi a mais frequente, sendo observada em 12,4% (76/613) dos casos, seguida por sola dupla 9,79% (60/613), laminite crônica 8,81% (54/613), úlcera de sola 7,83% (48/613) e a hiperplasia interdigital 7,24% (45/613). A laminite e suas consequências representaram 45% do total de lesões identificadas, acompanhadas por 36% das injúrias de causa secundárias ou incertas e de doenças infecciosas com 19%. A distribuição das lesões entre os membros foi de 68% nos pélvicos e 32% nos torácicos. As fêmeas criadas em sistema semi-intensivo, holandesas, com escore corporal III e porte grande eram mais acometidas. A claudicação estava presente em 78% dos animais, enquanto 10% não claudicavam. As taxas de letalidade e recuperação foram de 9% (31/334) e 73 % (243/334), respectivamente. No período chuvoso foram 51% dos casos e 49% na época seca. Os principais municípios de origem foram Bom Conselho 22,75% (76/334), Garanhuns 18, 86% (63/334) e Brejão 12,57% (42/334). O custo estimado com tratamento foi de US$ 150,13/caso. Provavelmente falhas de manejo nas propriedades foram importantes fatores de risco para as doenças. Sugere-se a implementação de medidas profiláticas para evitar as perdas econômicas associadas às enfermidades podais.

Cecocolic intussusception and cecal torsion in cattle / Intussuscepção cecocólica e torção de ceco em bovinos

This work aims to describe the clinical, laboratory, and anatomopathological findings of two bovines, one affected by cecocolic intussusception, and the other by dilation with cecal torsion. The clinical examination demonstrated metallic resonance from the right flank, ruminal and intestinal hypomotility, and abdominal distension, in addition to alterations in feces characteristics. Was observed in the two animals leukocytosis by neutrophilia with regenerative shift to the left, and hyperfibrinogenemia. The analysis of ruminal fluid revealed impairment of the microbiota and an increase in chloride levels. The laparoscopic examination performed on one of the animals showed dilation of the colon, the cecum with hyperemia and serous edema, with a dividing halo between affected and unaffected portions, in addition to reddish peritoneal fluid. In the laparotomy, an enlarged cecum was found, with gaseous and liquid contents, swollen and turgid colon, and peritonitis. In addition to the findings observed during surgery, the anatomopathological examination demonstrated, in bovine 01, intestinal intussusception in the region of the cecocolic valve, and, in bovine 02, twisting of the loop at the ileocecocolic junction. Despite the low occurrence of digestive system disorders in cattle, cecal torsion and intussusception represent serious intestinal clinical conditions. These reports take the attention to the importance of a multidisciplinary approach to provide a correct diagnosis of intestinal diseases.

O objetivo deste trabalho foi descrever os achados clínicos, laboratoriais e anatomopatológicos de dois bovinos, um acometido por intussuscepção cecocólica e o outro por dilatação com torção de ceco. O diagnóstico de ambos os casos foi base-ado nos achados clínicos, laboratoriais, videolaparoscópicos, cirúrgicos e anatomopatológicos. No exame clínico evidenciou-se ressonância metálica no flanco direito, hipomotilidade ruminal e intestinal, distensão abdominal, além de alteração nas carac-terísticas das fezes. Observou-se nos dois animais leucocitose por neutrofilia com desvio para esquerda regenerativo e hiperfi-brinogenia. A análise do fluido ruminal revelou comprometimento da microbiota e elevação nos teores de cloretos. O exame videolaparoscópico, realizado no bovino dois (02), evidenciou dilatação do cólon, ceco com hiperemia e edema de serosa com halo divisório entre porção acometida e não acometida, além de líquido peritoneal de coloração avermelhada. Na laparotomia constatou-se ceco dilatado por conteúdo gasoso e líquido, cólon edemaciado e túrgido e, peritonite. No exame anatomopato-lógico, constatou-se, no bovino um (01), intussuscepção intestinal na região de válvula ceco-cólica e, no bovino (02) torção de alça na junção ileocecocólica. Apesar da baixa ocorrência, a torção de ceco e a intussuscepção acarretam condição intestinal grave e devem ser inseridas na lista de diagnósticos diferenciais das enfermidades digestivas de bovinos. Estes relatos chamam a atenção para a importância da abordagem multidisciplinar no diagnóstico das enfermidades intestinais.

Cecocolic intussusception and cecal torsion in cattle / Intussuscepção cecocólica e torção de ceco em bovinos

This work aims to describe the clinical, laboratory, and anatomopathological findings of two bovines, one affected by cecocolic intussusception, and the other by dilation with cecal torsion. The clinical examination demonstrated metallic resonance from the right flank, ruminal and intestinal hypomotility, and abdominal distension, in addition to alterations in feces characteristics. Was observed in the two animals leukocytosis by neutrophilia with regenerative shift to the left, and hyperfibrinogenemia. The analysis of ruminal fluid revealed impairment of the microbiota and an increase in chloride levels. The laparoscopic examination performed on one of the animals showed dilation of the colon, the cecum with hyperemia and serous edema, with a dividing halo between affected and unaffected portions, in addition to reddish peritoneal fluid. In the laparotomy, an enlarged cecum was found, with gaseous and liquid contents, swollen and turgid colon, and peritonitis. In addition to the findings observed during surgery, the anatomopathological examination demonstrated, in bovine 01, intestinal intussusception in the region of the cecocolic valve, and, in bovine 02, twisting of the loop at the ileocecocolic junction. Despite the low occurrence of digestive system disorders in cattle, cecal torsion and intussusception represent serious intestinal clinical conditions. These reports take the attention to the importance of a multidisciplinary approach to provide a correct diagnosis of intestinal diseases.(AU)

O objetivo deste trabalho foi descrever os achados clínicos, laboratoriais e anatomopatológicos de dois bovinos, um acometido por intussuscepção cecocólica e o outro por dilatação com torção de ceco. O diagnóstico de ambos os casos foi base-ado nos achados clínicos, laboratoriais, videolaparoscópicos, cirúrgicos e anatomopatológicos. No exame clínico evidenciou-se ressonância metálica no flanco direito, hipomotilidade ruminal e intestinal, distensão abdominal, além de alteração nas carac-terísticas das fezes. Observou-se nos dois animais leucocitose por neutrofilia com desvio para esquerda regenerativo e hiperfi-brinogenia. A análise do fluido ruminal revelou comprometimento da microbiota e elevação nos teores de cloretos. O exame videolaparoscópico, realizado no bovino dois (02), evidenciou dilatação do cólon, ceco com hiperemia e edema de serosa com halo divisório entre porção acometida e não acometida, além de líquido peritoneal de coloração avermelhada. Na laparotomia constatou-se ceco dilatado por conteúdo gasoso e líquido, cólon edemaciado e túrgido e, peritonite. No exame anatomopato-lógico, constatou-se, no bovino um (01), intussuscepção intestinal na região de válvula ceco-cólica e, no bovino (02) torção de alça na junção ileocecocólica. Apesar da baixa ocorrência, a torção de ceco e a intussuscepção acarretam condição intestinal grave e devem ser inseridas na lista de diagnósticos diferenciais das enfermidades digestivas de bovinos. Estes relatos chamam a atenção para a importância da abordagem multidisciplinar no diagnóstico das enfermidades intestinais.(AU)

Ultrasonographic diagnosis of ileal intussusception in calf

Background: Intussusception, characterized by invagination of an intestinal segment into the lumen of the adjacent segment, is one of the main causes of intestinal obstruction in cattle, and occurs more frequently in calves. The diagnosis of the disease is based on the history, clinical examination, and complementary exams, which are a challenge in this species, especially in calves, in which transrectal palpation is limited. As it is a non-invasive, effective, and low-cost test, ultrasonography could be an important tool in the diagnosis of intestinal obstructions, in which time is essential for the prognosis. Therefore, the objective was to report a case of intussusception in a calf diagnosed by ultrasound. Case: A 4-month-old calf, weaned at 3 months and raised intensively, was treated at the Clínica de Bovinos de Garanhuns, campus of the Universidade Federal Rural de Pernambuco (CBG/UFRPE), with a history of apathy, anorexia, and dyschezia for 3 days. On physical examination, fever, moderate dehydration, tachycardia, tachypnea with polypnea, bilaterally bulging abdomen, sound of fluid on ballottement, ruminal and intestinal hypomotility, and melena were observed. The hematological findings revealed leukocytosis due to neutrophilia (degenerate neutrophils), hypoproteinemia, and hyperfibrinogenemia. The analysis of the ruminal fluid showed compromised microbiota and increased chloride content. The transabdominal ultrasonography demonstrated, in the right ventral region, hypermotile and full small bowel loops and an increase in the volume of the peritoneal fluid. In addition, there was a segment of the small intestine which, in cross-section, showed multiple concentric rings ("onion rings", "target pattern", or "bull's eye") and adherence to adjacent loops, compatible with intestinal obstruction due to intussusception. Due to the seriousness of the clinical condition and the ultrasound findings, the animal was euthanized and the necropsy revealed focal fibrinous peritonitis and intestinal obstruction due to intussusception in ileum intestinal segments. Discussion: Intussusception has previously been reported in calves, however this is the first report of ultrasound diagnosis of the disease in Brazil. Although the etiology is rarely confirmed, the age group and recent changes in diet (weaning) were predisposing factors. The history, clinical signs, and laboratory tests were similar to those described in cattle with intussusception, however they may be present in other gastrointestinal illnesses. Other authors have also reported that the nonspecificity of the signs and the impossibility of performing transrectal palpation made it difficult to diagnose intestinal obstruction in calves without the use of other diagnostic tools. As it is a non-invasive and accurate technique, ultrasound has been used in ruminants for diagnostic purposes, including intestinal obstructions. In the present case, the main findings are described as the presence of a lesion with the appearance of multiple concentric rings, hypermotile, dilated, and full intestinal loops. The pathological findings were compatible with the ultrasound images and similar to those described by other authors, confirming the diagnosis. The use of ultrasonography as a diagnostic tool in cattle should be expanded, aiming at the early determination of diagnosis and prognosis, to reduce producer costs and animal discomfort. In cases of intussusception, late diagnosis makes treatment unfeasible.

Íleo paralítico em três bovinos: relato de caso / Paralytic ileus in three cattle: case report

O íleo paralítico é uma obstrução do tipo funcional, na qual o lúmen intestinal está patente, comprometendo a passagem da ingesta no intestino. Este relato objetiva descrever três casos em vacas com aptidão leiteira, atendidos na rotina hospitalar e diagnosticados com íleo paralítico. Em seus históricos, os proprietários queixavam-se que os animais apresentavam redução do apetite, timpania ruminal, diminuição da produção de leite e eliminação das fezes. Ao exame físico, alguns sinais clínicos apresentaram destaque, como apatia, desidratação, redução da motilidade ruminal e intestinal, fezes em pequena quantidade e com muco, distensão do abdômen e ao balotamento constatou-se a presença de líquido. Na análise do fluido ruminal todos os animais apresentaram o teor de cloreto elevado (>30 mEq/L), caracterizando, dessa forma, um processo obstrutivo. Diante dos achados, suspeitou-se inicialmente de um quadro de obstrução intestinal. Nos casos, a conduta adotada foi realizar uma laparotomia exploratória através do flanco direito, porém constatou-se, que não existia qualquer segmento com obstrução de natureza mecânica, que justificasse as alterações físicas e laboratoriais encontradas. Diante destes resultados, configurou-se um quadro clínico indicativo de íleo paralítico. As vacasforam submetidas a um protocolo terapêutico pós-cirúrgico composto por antibioticoterapia, anti-inflamatório, cálcio, procinético e tratamento de suporte. Os animais manifestaram uma resposta favorável a conduta terapêutica, com restabelecimento da função gastrointestinal e dos demais parâmetros fisiológicos, recebendo alta após uma evolução clínica variando entre dez a doze dias.

Paralytic ileus is an obstruction of the functional type, in which the intestinal lumen is patent, compromising the passage of the intake in the intestine. The objective of this study was to describe three cases in dairy cows treated in the hospital routine diagnosed with paralytic ileus. In their histories, the owners complained that the animals presented reduced appetite, ruminal tympany, decreased milk yield and elimination of faeces. At the physical examination, some clinical signs were prominent in both, such as apathy, dehydration, reduction of ruminal and intestinal motility, faeces were present in small quantity and with mucus present, abdominal enlargement and the succession produced sloshing sounds. In the analysis of the ruminal fluid, the chloride content in both was high (>30 mEq/L), characterizing an obstructive process. In the face of the findings, a diagnosis of intestinal obstruction was initially suspected. In animals, the adopted approach was to perform an exploratory laparotomy through the right flank, but it was verified that there was no segment with mechanical obstruction that justified the physical and laboratorial alterations found. In view of these results, a clinical diagnosis indicative of paralytic ileus was established. The three animals were submitted to a post-surgical therapeutic protocol consisting of antibiotic therapy, anti-inflammatory, calcium, pro-kinetic and supportive treatment. The animals showed a favourable response to therapeutic treatment, with restoration of gastrointestinal function and other physiological parameters, and was discharged after a clinical evolution ranging from ten to twelve days.

Íleo paralítico em três bovinos: Relato de caso / Paralytic ileus in three cattle: case report

O íleo paralítico é uma obstrução do tipo funcional, na qual o lúmen intestinal está patente, comprometendo a passagem da ingesta no intestino. Este relato objetiva descrever três casos em vacas com aptidão leiteira, atendidos na rotina hospitalar e diagnosticados com íleo paralítico. Em seus históricos, os proprietários queixavam-se que os animais apresentavam redução do apetite, timpania ruminal, diminuição da produção de leite e eliminação das fezes. Ao exame físico, alguns sinais clínicos apresentaram destaque, como apatia, desidratação, redução da motilidade ruminal e intestinal, fezes em pequena quantidade e com muco, distensão do abdômen e ao balotamento constatou-se a presença de líquido. Na análise do fluido ruminal todos os animais apresentaram o teor de cloreto elevado (>30 mEq/L), caracterizando, dessa forma, um processo obstrutivo. Diante dos achados, suspeitou-se inicialmente de um quadro de obstrução intestinal. Nos casos, a conduta adotada foi realizar uma laparotomia exploratória através do flanco direito, porém constatou-se, que não existia qualquer segmento com obstrução de natureza mecânica, que justificasse as alterações físicas e laboratoriais encontradas. Diante destes resultados, configurou-se um quadro clínico indicativo de íleo paralítico. As vacas foram submetidas a um protocolo terapêutico pós-cirúrgico composto por antibioticoterapia, anti-inflam

Paralytic ileus is an obstruction of the functional type, in which the intestinal lumen is patent, compromising the passage of the intake in the intestine. The objective of this study was to describe three cases in dairy cows treated in the hospital routine diagnosed with paralytic ileus. In their histories, the owners complained that the animals presented reduced appetite, ruminal tympany, decreased milk yield and elimination of faeces. At the physical examination, some clinical signs were prominent in both, such as apathy, dehydration, reduction of ruminal and intestinal motility, faeces were present in small quantity and with mucus present, abdominal enlargement and the succession produced sloshing sounds. In the analysis of the ruminal fluid, the chloride content in both was high (>30 mEq/L), characterizing an obstructive process. In the face of the findings, a diagnosis of intestinal obstruction was initially suspected. In animals, the adopted approach was to perform an exploratory laparotomy through the right flank, but it was verified that there was no segment with mechanical obstruction that justified the physical and laboratorial alterations found. In view of these results, a clinical diagnosis indicative of paralytic ileus was established. The three animals were submitted to a post-surgical therapeutic protocol consisting of antibiotic therapy, anti-inflammatory, calcium, pro-kinetic and supportive treatment. The animals showed a favourable response to therapeutic treatment, with restoration of gastrointestinal function and other physiological parameters, and was discharged after a clinical evolution ranging from ten to twelve days.

Cardiac, energy and hormonal blood markers, and lactatemia in cows with displaced abomasum

Background: Displaced abomasum (DA) is a common and economically important disorder that affects dairy cattle. Nutritional factors and adaptive responses that occur in the peripartum play a central role in the pathogenesis. The measurement of blood metabolites represents a useful tool for monitoring and prognostic determination in affected animals. Therefore, the objective was to evaluate cardiac, energy and hormonal blood markers, lactatemia, and insulin sensitivity in cows diagnosed with right displaced abomasum (RDA) and left displaced abomasum (LDA), comparing them with each other. Materials, Methods & Results: Nineteen cases of abomasum displacement in cows were studied, including 9 cases of RDA and 10 cases of LDA. The diagnosis was established by means of physical examination and measurement of the concentration of chlorides in the ruminal fluid (> 30 mEq/L). After diagnosis, clinical-surgical therapeutic management was instituted. At the time of diagnosis (M1) and at the resolution of the case (M2), blood samples were collected to assess the variables: non-esterified fatty acids (NEFA), beta hydroxybutyrate (βHB), L-lactate, creatine kinase (CK), creatine kinase MB (CK-MB), cardiac troponin I (cTnI), lactate dehydrogenase (LDH), glucose, insulin, and cortisol. In addition, insulin sensitivity was estimated using the Revised Quantitative Insulin Sensitivity Check Index (RQUICKI) and RQUICKI-βHB. The means of the variables were compared, separating the effects of groups (RDA and LDA) and moments (M1 and M2), at the level of 5% probability. The concentrations of NEFA, CK-MB, L-lactate, glucose, insulin, and cortisol were higher at M1 and the RQUICKI and RQUICKI-βHB indices were lower at this moment. L-lactate, CK, and CK-MB were higher in the RDA group, while cTnI, βHB, and LDH did not present a group or moment effect. Cardiac markers correlated with the energy profile metabolites, L-lactate, and cortisol. Discussion: The high...

Íleo paralítico em três bovinos: Relato de caso / Paralytic ileus in three cattle: case report

O íleo paralítico é uma obstrução do tipo funcional, na qual o lúmen intestinal está patente, comprometendo a passagem da ingesta no intestino. Este relato objetiva descrever três casos em vacas com aptidão leiteira, atendidos na rotina hospitalar e diagnosticados com íleo paralítico. Em seus históricos, os proprietários queixavam-se que os animais apresentavam redução do apetite, timpania ruminal, diminuição da produção de leite e eliminação das fezes. Ao exame físico, alguns sinais clínicos apresentaram destaque, como apatia, desidratação, redução da motilidade ruminal e intestinal, fezes em pequena quantidade e com muco, distensão do abdômen e ao balotamento constatou-se a presença de líquido. Na análise do fluido ruminal todos os animais apresentaram o teor de cloreto elevado (>30 mEq/L), caracterizando, dessa forma, um processo obstrutivo. Diante dos achados, suspeitou-se inicialmente de um quadro de obstrução intestinal. Nos casos, a conduta adotada foi realizar uma laparotomia exploratória através do flanco direito, porém constatou-se, que não existia qualquer segmento com obstrução de natureza mecânica, que justificasse as alterações físicas e laboratoriais encontradas. Diante destes resultados, configurou-se um quadro clínico indicativo de íleo paralítico. As vacas foram submetidas a um protocolo terapêutico pós-cirúrgico composto por antibioticoterapia, anti-inflam

Paralytic ileus is an obstruction of the functional type, in which the intestinal lumen is patent, compromising the passage of the intake in the intestine. The objective of this study was to describe three cases in dairy cows treated in the hospital routine diagnosed with paralytic ileus. In their histories, the owners complained that the animals presented reduced appetite, ruminal tympany, decreased milk yield and elimination of faeces. At the physical examination, some clinical signs were prominent in both, such as apathy, dehydration, reduction of ruminal and intestinal motility, faeces were present in small quantity and with mucus present, abdominal enlargement and the succession produced sloshing sounds. In the analysis of the ruminal fluid, the chloride content in both was high (>30 mEq/L), characterizing an obstructive process. In the face of the findings, a diagnosis of intestinal obstruction was initially suspected. In animals, the adopted approach was to perform an exploratory laparotomy through the right flank, but it was verified that there was no segment with mechanical obstruction that justified the physical and laboratorial alterations found. In view of these results, a clinical diagnosis indicative of paralytic ileus was established. The three animals were submitted to a post-surgical therapeutic protocol consisting of antibiotic therapy, anti-inflammatory, calcium, pro-kinetic and supportive treatment. The animals showed a favourable response to therapeutic treatment, with restoration of gastrointestinal function and other physiological parameters, and was discharged after a clinical evolution ranging from ten to twelve days.(AU)

Diagnóstico ultrassonográfico de distúrbios reprodutivos em pequenos ruminantes / Ultrasonographic diagnosis of reproductive disorders in small ruminants

A ultrassonografia (USG) é uma técnica de imagem em tempo real e pouco invasiva. Na produção de ovinos e caprinos, a USG vem sendo utilizada como uma ferramenta auxiliar no manejo reprodutivo, assim como no diagnóstico clínico-reprodutivo de doenças ginecológicas, obstétricas e andrológicas. Por meio da USG é possível a realização de exames em série para monitorar a progressão de uma anormalidade, resposta ao tratamento ou a funcionalidade e morfologia do órgão. Assim, por meio da USG são fornecidas informações substanciais ao profissional do campo e da pesquisa auxiliando na definição de prognósticos, tratamentos, descarte zootécnico e, ainda, na aquisição de reprodutores e matrizes sem distúrbios reprodutivos adquiridos ou congênitos.

Ultrasonography (USG) is a less invasive, real-time imaging modality. In the sheep and goat farming, USG has been used as an auxiliary tool in the reproductive management, as well as in the clinical-reproductive diagnosis of gynecological, obstetric and andrological disorders. Through the USG, it is possible to perform successive evaluations to monitor the progression of an abnormality, response to treatment or organ function and morphology. Therefore, through USG are provide substantial information to the practical and research veterinarian and assists in the definition of prognostics, treatments, culling and on the acquisition of breeding males and females without acquired or congenital reproductive disorders.

Primary pulmonary adenocarcinoma in a cow

Background: Primary neoplasms of the respiratory tract are rare in cattle, and they present with nonspecific clinical signs and are usually found at post-mortem. Pulmonary adenocarcinoma of the acinar type is uncommon, and information about this neoplasm in cattle is scarce. This paper aims to describe the clinical, laboratory, and pathological findings in a cow with this neoplasm. Case: A 10-year-old, adult, mixed-breed Holstein cow weighing 300 kg was referred to the Garanhuns Cattle Clinic of the Campus of Federal Rural University of Pernambuco, Brazil, with a history of decreased appetite, tiredness, weight loss, and difficulty in breathing for two months. The animal had been treated at the farm of origin with enrofloxacin, florfenicol, and flunixin meglumine. The animal’s appetite improved, but no improvement in the respiratory symptoms was observed. On examination at our center, the cow was in an orthopedic position, with neck extension and elbow abduction; and it remainedin a recumbent position. The cow had neutrophilia, normochromic normocytic anemia, and hyperfibrinogemia. The body condition score (BCS) was 1 (BCS ranges from 1 to 5), and the cow had moderate enophthalmia, serous secretions in nostrils, tachycardia, and tachypnea. It also had increased breathing intensity; increased breath sounds in the cranial regions of both lungs; areas of reduced breath sounds in the medial portions of the lungs; intermittent wheezing in the cranial region of the left lung medially and in the cranial region of the right lung medially; intermittent crepitations in the cranial region of the right lung medially; reduced thoracic expansion; and expiratory dyspnea. Pulmonary ultrasonography revealed hyperechogenic multifocal structures in both lungs. In view of the severe clinical condition and unfavorable prognosis, theowner opted for euthanasia. Necropsy revealed that there was a significant amount of yellow fluid in the thoracic cavity, and...

Diagnóstico ultrassonográfico de distúrbios reprodutivos em pequenos ruminantes / Ultrasonographic diagnosis of reproductive disorders in small ruminants

A ultrassonografia (USG) é uma técnica de imagem em tempo real e pouco invasiva. Na produção de ovinos e caprinos, a USG vem sendo utilizada como uma ferramenta auxiliar no manejo reprodutivo, assim como no diagnóstico clínico-reprodutivo de doenças ginecológicas, obstétricas e andrológicas. Por meio da USG é possível a realização de exames em série para monitorar a progressão de uma anormalidade, resposta ao tratamento ou a funcionalidade e morfologia do órgão. Assim, por meio da USG são fornecidas informações substanciais ao profissional do campo e da pesquisa auxiliando na definição de prognósticos, tratamentos, descarte zootécnico e, ainda, na aquisição de reprodutores e matrizes sem distúrbios reprodutivos adquiridos ou congênitos.(AU)

Ultrasonography (USG) is a less invasive, real-time imaging modality. In the sheep and goat farming, USG has been used as an auxiliary tool in the reproductive management, as well as in the clinical-reproductive diagnosis of gynecological, obstetric and andrological disorders. Through the USG, it is possible to perform successive evaluations to monitor the progression of an abnormality, response to treatment or organ function and morphology. Therefore, through USG are provide substantial information to the practical and research veterinarian and assists in the definition of prognostics, treatments, culling and on the acquisition of breeding males and females without acquired or congenital reproductive disorders.(AU)

Primary pulmonary adenocarcinoma in a cow

Background: Primary neoplasms of the respiratory tract are rare in cattle, and they present with nonspecific clinical signs and are usually found at post-mortem. Pulmonary adenocarcinoma of the acinar type is uncommon, and information about this neoplasm in cattle is scarce. This paper aims to describe the clinical, laboratory, and pathological findings in a cow with this neoplasm. Case: A 10-year-old, adult, mixed-breed Holstein cow weighing 300 kg was referred to the Garanhuns Cattle Clinic of the Campus of Federal Rural University of Pernambuco, Brazil, with a history of decreased appetite, tiredness, weight loss, and difficulty in breathing for two months. The animal had been treated at the farm of origin with enrofloxacin, florfenicol, and flunixin meglumine. The animals appetite improved, but no improvement in the respiratory symptoms was observed. On examination at our center, the cow was in an orthopedic position, with neck extension and elbow abduction; and it remainedin a recumbent position. The cow had neutrophilia, normochromic normocytic anemia, and hyperfibrinogemia. The body condition score (BCS) was 1 (BCS ranges from 1 to 5), and the cow had moderate enophthalmia, serous secretions in nostrils, tachycardia, and tachypnea. It also had increased breathing intensity; increased breath sounds in the cranial regions of both lungs; areas of reduced breath sounds in the medial portions of the lungs; intermittent wheezing in the cranial region of the left lung medially and in the cranial region of the right lung medially; intermittent crepitations in the cranial region of the right lung medially; reduced thoracic expansion; and expiratory dyspnea. Pulmonary ultrasonography revealed hyperechogenic multifocal structures in both lungs. In view of the severe clinical condition and unfavorable prognosis, theowner opted for euthanasia. Necropsy revealed that there was a significant amount of yellow fluid in the thoracic cavity, and...(AU)

Serum protein electrophoresis in goats with pregnancy toxemia / Proteinograma de cabras com toxemia da prenhez

Studies on pregnancy toxemia (TP) in goats, when compared with ovine, have been less common, and there are no reports in Brazil that include serum protein electrophoresis in goats with the naturally occurring form of the disease. As such, serum protein electrophoresis in goats with TP was performed to evaluate the biological behavior of acute phase proteins (PFA), as well as biochemical and hormonal indicators of this disease. Thirty-six goats diagnosed with TP were evaluated in the Bovine Clinic Garanhuns Campus/UFRPE and private properties. The goats underwent physical exam and ultrasound, followed by collection of blood and urine for laboratory exams. The goats had clinical signs of TP, with elevated levels of beta-hydroxybutyrate (BHB) and non-esterified fatty acids (AGNE), and normal glucose levels. Ketonuria was seen in all animals. On serum protein electrophoresis, there were elevated levels of haptoglobin. The hormone profile showed elevated levels of cortisol and decreased levels of insulin. In conclusion, the severe metabolic disturbance caused by TP in goats causes an elevation of serum levels of haptoglobin, as well as changes in the biochemical and hormonal profiles, which reflect significant alterations in lipid metabolism.(AU)

Os estudos sobre a toxemia da prenhez (TP) em caprinos, quando comparados aos ovinos, têm sido menos frequentes, não havendo relatos no Brasil sobre o proteinograma de cabras acometidas por casos clínicos naturais da doença. Assim, realizou-se o proteinograma de cabras com TP, visando avaliar o comportamento biológico das proteínas de fase aguda (PFA), além de indicadores bioquímicos e hormonais nesta enfermidade. Foram avaliadas 36 cabras diagnosticadas com TP, na Clínica de Bovinos - campus Garanhuns/UFRPE e em propriedades. Os animais foram submetidos ao exame clínico e ultrassonográfico, seguido de coleta de sangue e urina para exames laboratoriais. As cabras apresentaram sinais clínicos de TP, com valores de beta-hidroxibutirato (BHB) e ácidos graxos não esterificados (AGNE) elevados e glicose normal. Cetonúria foi observada em todos os animais. No proteinograma, houve aumento nos níveis séricos de haptoglobina. O perfil hormonal revelou níveis séricos elevados de cortisol e reduzidos de insulina. Em conclusão, o severo transtorno metabólico provocado pela TP em cabras provoca elevação dos níveis séricos de haptoglobina, além das alterações no perfil bioquímico e hormonal, refletindo marcantes modificações no metabolismo lipídico.(AU)

Proteinograma de cabras acometidas por toxemia da prenhez / Serum protein electrophoresis in goats with pregnancy toxemia

Os estudos sobre a toxemia da prenhez (TP) em caprinos, quando comparados aos ovinos, têm sido menos frequentes, não havendo relatos no Brasil sobre o proteinograma de cabras acometidas por casos clínicos naturais da doença. Assim, realizouse o proteinograma de cabras com TP, visando avaliar o comportamento biológico das proteínas de fase aguda (PFA), além de indicadores bioquímicos e hormonais nesta enfermidade. Foram avaliadas 36 cabras diagnosticadas com TP, na Clínica de Bovinos - campus Garanhuns/UFRPE e em propriedades. Os animais foram submetidos ao exame clínico e ultrassonográfico, seguido de coleta de sangue e urina para exames laboratoriais. As cabras apresentaram sinais clínicos de TP, com valores de beta-hidroxibutirato (BHB) e ácidos graxos não esterificados (AGNE) elevados e glicose normal. Cetonúria foi observada em todos os animais. No proteinograma, houve aumento nos níveis séricos de haptoglobina. O perfil hormonal revelou níveis séricos elevados de cortisol e reduzidos de insulina. Em conclusão, o severo transtorno metabólico provocado pela TP em cabras provoca elevação dos níveis séricos de haptoglobina, além das alterações no perfil bioquímico e hormonal, refletindo marcantes modificações no metabolismo lipídico.

Studies on pregnancy toxemia (TP) in goats, when compared with ovine, have been less common, and there are no reports in Brazil that include serum protein electrophoresis in goats with the naturally occurring form of the disease. As such, serum protein electrophoresis in goats with TP was performed to evaluate the biological behavior of acute phase proteins (PFA), as well as biochemical and hormonal indicators of this disease. Thirty-six goats diagnosed with TP were evaluated in the Bovine Clinic ­ Garanhuns Campus/UFRPE and private properties. The goats underwent physical exam and ultrasound, followed by collection of blood and urine for laboratory exams. The goats had clinical signs of TP, with elevated levels of beta-hydroxybutyrate (BHB) and non-esterified fatty acids (AGNE), and normal glucose levels. Ketonuria was seen in all animals. On serum protein electrophoresis, there were elevated levels of haptoglobin. The hormone profile showed elevated levels of cortisol and decreased levels of insulin. In conclusion, the severe metabolic disturbance caused by TP in goats causes an elevation of serum levels of haptoglobin, as well as changes in the biochemical and hormonal profiles, which reflect significant alterations in lipid metabolism.

EFEITO DA MONENSINA SÓDICA SOBRE O PERFIL METABÓLICO DE OVELHAS ANTES E APÓS O PARTO

Abstract The study was carried out to analyze the effect of monensin supplementation during 60 days prior to parturition, and 30 days postpartum, on the metabolic and hormonal profile of ewes. Pregnant ewes (n=13) were randomly divided into two groups: monensin group (n = 7; 30 mg/day) and control group (n = 6). Blood and ruminal fluid samples were collected 60, 50, 40, 30, 20 and 10 days prior to parturition, at the time of parturition and on 10, 20 and 30 days postpartum. The following variables were analyzed: glucose, fructosamine, non-esterfied fatty acids, -hydroxybutyrate, cholesterol, triglycerides, total protein, albumin, urea and ketone bodies in the urine. The hormonal determinations were cortisol and insulin. The analysis of the ruminal fluid involved pH and concentration of volatile fatty acids. The statistical analysis involved ANOVA and correlation studies (P 0,05). Monensin increased (P 0,05) the propionic acid concentration in the rumen and blood fructosamine and insulin. The administration of monensin improved some indicators of energy balance.

Resumo O estudo foi realizado com o intuito de avaliar o efeito da monensina, suplementada a partir de 60 dias antes do parto (dap) e por 30 dias pós-parto, sobre o perfil metabólico e hormonal de ovelhas. As ovelhas prenhas (n=13), foram divididas, de forma aleatória, em dois grupos, um que recebeu a monensina (n=7) (30 mg/dia) e o controle (n=6). Amostras de sangue e fluido ruminal foram colhidas aos 60, 50, 40, 30, 20 e 10 dias antes do parto, no momento do parto e nos 10, 20 e 30 dias pós-parto. As variáveis mensuradas foram: glicose, frutosamina, ácidos graxos não esterificados (AGNEs), -hidroxibutirato, colesterol, triglicérides, proteína total, albumina, ureia e pesquisa de corpos cetônicos na urina. As determinações hormonais foram cortisol e a insulina. No fluido ruminal foi determinado o pH e a concentração dos ácidos graxos voláteis. Na análise estatística foi empregada a ANOVA e estudo de correlação (P 0,05). A monensina elevou (P 0,05) a concentração do propionato no rúmen e frutosamina e insulina no sangue. A administração da monensina promoveu melhora em alguns indicadores do balanço energético.

Clinical and laboratory findings in calves of dairy Gir with "the rumenal drinking" / Achados clínicos e laboratoriais em bezerros da raça Gir leiteira com síndrome do bebedor rumenal

The syndrome ruminal drinker or ruminal drinking, is a clinical condition that occurs in infants calves for failure to closing reflection of esophageal groove and which carries most of the time in a ruminal acidosis. The aim of this study was to describe the clinical and laboratory findings in eleven affected calves with the disease treated at Garanhuns cattle Clinic of the Federal Rural University of Pernambuco, CBG-UFRPE. The main systemic and digestive clinical signs were apathy, lack of appetite, lack of sucking reflex, timpania, liquid sound to balotamento. hematologic and ruminal fluid analyzes were performed.Among the changes found in the blood count as the leukocyte response drew attention one leukocytosis by neutrophilia with a shift to regenerative left, plus a slight hypoproteinemia and hyperfibrinogenemia. In ruminal fluid analysis were observed changes as whitish presence of milk clots, altered odor and acid pH. The established therapeutic approach was sinfonagem of ruminal content, and administration of medications for other illnesses involved in the process for an average period of 20 days until discharge. Although the literature cite the low occurrence of the disease, this accounted for 12.34% of the diseases that attacked the calves treated at CBG-UFRPE within one year.(AU)

A síndrome do bebedor rumenal ou rumenal drinking, é uma condição clínica que ocorre em bezerros lactentes por falha no reflexo de fechamento da goteira esofágica e que acarreta na maioria das vezes em uma acidose rumenal. O objetivo deste trabalho foi descrever os achados clínicos e laboratoriais em onze bezerros acometidos com a enfermidade, atendidos na Clínica de Bovinos de Garanhuns da Universidade Federal Rural de Pernambuco, CBG-UFRPE. Os principais sinais clínicos sistêmicos e digestivos foram: apatia, inapetência, ausência do reflexo de sucção, timpania, som de líquido ao balotamento. Foram realizadas análises hematológicas e de fluído rumenal.Dentre as alterações encontradas no hemograma quanto à resposta leucocitária chamou a atenção uma leucocitose por neutrofilia com desvio a esquerda regenerativo, além de uma discreta hipoproteinemia e hiperfibrinogenemia. Na análise de fluído rumenal observaram-se alterações como coloração esbranquiçada, presença de coágulos de leite, odor alterado e o pH ácido. A conduta terapêutica instituída foi a sinfonagem do conteúdo rumenal, além de administração de medicamentos para outras enfermidades envolvidas no processo por um período médio de 20 dias até receberem alta. Embora a literatura cite a baixa ocorrência da enfermidade, esta foi responsável por 12,34% das doenças que acometeram os bezerros atendidos na CBG-UFRPE no período de um ano.(AU)

Effect of monensin sodium on metabolic profile of ewes before and pospartum / Efeito da monensina sódica sobre o perfil metabólico de ovelhas antes e após o parto

The study was carried out to analyze the effect of monensin supplementation during 60 days prior to parturition, and 30 days postpartum, on the metabolic and hormonal profile of ewes. Pregnant ewes (n=13) were randomly divided into two groups: monensin group (n = 7; 30 mg/day) and control group (n = 6). Blood and ruminal fluid samples were collected 60, 50, 40, 30, 20 and 10 days prior to parturition, at the time of parturition and on 10, 20 and 30 days postpartum. The following variables were analyzed: glucose, fructosamine, non-esterfied fatty acids, ?-hydroxybutyrate, cholesterol, triglycerides, total protein, albumin, urea and ketone bodies in the urine. The hormonal determinations were cortisol and insulin. The analysis of the ruminal fluid involved pH and concentration of volatile fatty acids. The statistical analysis involved ANOVA and correlation studies (P 0,05). Monensin increased (P 0,05) the propionic acid concentration in the rumen and blood fructosamine and insulin. The administration of monensin improved some indicators of energy balance(AU)

O estudo foi realizado com o intuito de avaliar o efeito da monensina, suplementada a partir de 60 dias antes do parto (dap) e por 30 dias pós-parto, sobre o perfil metabólico e hormonal de ovelhas. As ovelhas prenhas (n=13), foram divididas, de forma aleatória, em dois grupos, um que recebeu a monensina (n=7) (30 mg/dia) e o controle (n=6). Amostras de sangue e fluido ruminal foram colhidas aos 60, 50, 40, 30, 20 e 10 dias antes do parto, no momento do parto e nos 10, 20 e 30 dias pós-parto. As variáveis mensuradas foram: glicose, frutosamina, ácidos graxos não esterificados (AGNEs), ?-hidroxibutirato, colesterol, triglicérides, proteína total, albumina, ureia e pesquisa de corpos cetônicos na urina. As determinações hormonais foram cortisol e a insulina. No fluido ruminal foi determinado o pH e a concentração dos ácidos graxos voláteis. Na análise estatística foi empregada a ANOVA e estudo de correlação (P 0,05). A monensina elevou (P 0,05) a concentração do propionato no rúmen e frutosamina e insulina no sangue. A administração da monensina promoveu melhora em alguns indicadores do balanço energético(AU)