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1.
J Coll Physicians Surg Pak ; 32(12): 1623-1625, 2022 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-36474389

RESUMEN

This is the first case report of Mondor's disease diagnosed in a marathon runner developed due to tight heart rate strap. A 41-year female marathon runner was admitted to the hospital with a cord-like soft tissue swelling under her breast, which was confirmed by physical examination. She had a history of severe exercise; during which, she used a sports watch with a heart rate strap that she tightened under her bra. Doppler ultrasonography revealed a superficial non-compressible thrombosed vein compatible with Mondor's disease. Key Words: Mondor's disease, Ultrasonography, Heart rate strap.


Asunto(s)
Ejercicio Físico , Femenino , Humanos , Frecuencia Cardíaca
2.
Photodiagnosis Photodyn Ther ; 40: 103096, 2022 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-36049717

RESUMEN

In this study, we investigated the elasticity of the optic nerve using shear wave elastography (SWE) in patients with Behçet's Disease (BD) and compare findings with a healthy control group. Optic nerve measurements of 40 eyes in the BD group and 38 eyes in the control group were performed by SWE (SWE-right and SWE-left). The mean age of the individuals in the BD group was higher than controls (p = 0.022). The SWE measurement results in the right eye were significantly higher in the BD group (p = 0.005), while SWE-left values were similar in the two groups (p = 0.206). There was a moderate positive correlation between age and SWE-right (r = 0.347, p = 0.031), there was no correlation between SWE-left and age (p = 0.756). It was found that SWE-right had significant value in distinguishing between BD and healthy controls (sensitivity: 75%, specificity: 78.9%; p = 0.005); whereas, SWE-left did not (p = 0.206). In the multiple logistic regression analysis, after adjusting for age and sex, the performance of SWE-right to distinguish BD patients from controls was found to remain significant (OR: 15.045, 95% CI: 2.33-97.120, p = 0.004). Due to the fact that only SWE-right values appear to have significant discriminatory performance for BD, it is feasible to suggest that the frequency and severity of BD involvement are associated with SWE-related changes in the optic nerve. This finding indicates the need for more comprehensive studies evaluating optic nerve SWE values in this context.


Asunto(s)
Síndrome de Behçet , Diagnóstico por Imagen de Elasticidad , Fotoquimioterapia , Humanos , Síndrome de Behçet/diagnóstico por imagen , Fotoquimioterapia/métodos , Diagnóstico por Imagen de Elasticidad/métodos
3.
J Coll Physicians Surg Pak ; 32(4): 525-527, 2022 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-35330530

RESUMEN

Dermoid cysts (DCs) are benign, congenital tumors that comprise 0.04-0.6% of all intracranial tumors. DC rupture is a rare complication and usually occurs spontaneously. The most common localisations of intracranial DCs are the posterior fossa, and suprasellar and parasellar regions. The presentations of DCs are highly variable. They are often detected incidentally on computed tomography (CT) or magnetic resonance imaging (MRI) scans while investigating the cause of seizure or headache. Prepontine cystern is a rare localisation for intracranial DCs. To the best of our knowledge, only four cases have been reported in the literature so far. We present MRI and CT findings of a patient with DC, which ruptured into the subarachnoid space extending from the right Meckel's cave to the prepontine cistern. Key Words: Dermoid cysts, Meckel's cave, Prepontine cistern, Rupture.


Asunto(s)
Neoplasias Encefálicas , Quiste Dermoide , Quiste Dermoide/diagnóstico por imagen , Quiste Dermoide/cirugía , Humanos , Imagen por Resonancia Magnética , Rotura Espontánea/complicaciones , Tomografía Computarizada por Rayos X
4.
J Ultrasound Med ; 41(9): 2237-2246, 2022 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-34862639

RESUMEN

OBJECTIVES: To compare semiprofessional athletes and nonexercising individuals in terms of p-SWE properties of the patellar ligament and the Achilles tendon. METHODS: This case-control study was conducted in University of Health Sciences, Haseki Education and Research Hospital. A total of 58 individuals, with 29 in each group (according to power analysis), were included in the study. All relevant findings, including demographic characteristics, body mass index (BMI), and exercise (km run per week, km/w) were recorded. The MyLab 9 (Esaote, Genova, Italy) device was used for SWE. The QElaXto-p-SWE software was utilized for P-SWE interpretation and analyses. RESULTS: The mean age was 47.21 ± 12.16 years (range 22-70). Weight (P = .001) and BMI (P < .001) values were significantly higher in the nonathlete group than in the athlete group. There were no significant differences between groups in terms of age, gender, and height. Median SWE values of bilateral patellar ligaments (P < .001 and P < .001) and bilateral Achilles tendons (P < .001 and P < .001) were significantly higher in the athlete group than in the nonathlete group. CONCLUSIONS: We revealed normal p-SWE characteristics for the patellar ligament and Achilles tendon, which are frequently injured in athletes. These scores are important in early detection and follow-up of injuries in athletes.


Asunto(s)
Tendón Calcáneo , Diagnóstico por Imagen de Elasticidad , Ligamento Rotuliano , Tendinopatía , Tendón Calcáneo/diagnóstico por imagen , Adulto , Anciano , Atletas , Estudios de Casos y Controles , Humanos , Persona de Mediana Edad , Ligamento Rotuliano/diagnóstico por imagen , Adulto Joven
5.
Pol J Radiol ; 86: e387-e393, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34322189

RESUMEN

PURPOSE: In this retrospective study, we aimed to investigate the possible effects of transitional vertebra anatomy on facet joint tropism and orientation by evaluating lumbar magnetic resonance imaging (MRI) studies performed at our institution. MATERIAL AND METHODS: We included 84 patients with sacralization of the L5 vertebra and an equal number of patients with a radiology report within normal limits as the control group in our study. We compared facet tropism (FT) and orientation between both groups. RESULTS: In both the sacralization group and the control group, the facet orientation angle showed a significant increasing trend from the L1-L2 level to the L5-S1 level (p < 0.001). The orientation angle of the L5-S1 level was higher in the sacralization group compared to the control group (p < 0.01). In the evaluation of FJ orientation between the sacralization and control groups, we found that coronal orientation was significantly more frequent at the L5-S1 level in the sacralization group. When the 2 groups were compared with regard to tropism at each spinal level, the sacralization group had a significantly higher FT frequency at the L5-S1 level (p < 0.001). CONCLUSIONS: To our knowledge, this is the first study to evaluate the relationship between sacralization and facet joint tropism. However, there were no relationships between facet degeneration, disc degeneration/herniation, and sacralization. Our results indicate that, although patients with sacralization and controls had similar characteristics in most assessments, they demonstrated significant differences at the L5-S1 level in terms of orientation and tropism.

6.
J Forensic Leg Med ; 81: 102202, 2021 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-34153884

RESUMEN

OBJECTIVE: The aim of this study was to present our experience on the evaluation of suspected illicit drug carriers via computerized tomography scout view (CTSV) with analysis of detectability and features such as content, form and density. METHODS: A total of 120 individuals suspected of body packing were screened via CT in a university emergency department between January 2014 and December 2017. RESULTS: 88.3% of 120 body packing cases examined in the study were male. The median (1st quartile-3rd quartile) age of the cases was 35.5 (30-41) years. We found that solid packs have a 4.573-fold higher likelihood of detection in CTSV screening than liquid ones (95%CI: 1.879-11.134). Additionally, the number of CT scans needed were significantly associated with capsule localization (stomach) (OR:7.178, 95%CI: 2.420-21.293) and solid form packs (OR: 8.705, 95%CI: 2.318-32.692) are associated with number of CT scans. CONCLUSION: CTSVs have a successful detection rate, especially in solid form packs. Our results suggest that conclusive CTSV imaging for body packing may be recommended to delay the application of the next CT scan until the passage of the first capsule; thereby preventing unnecessary radiation exposure.


Asunto(s)
Transporte Intracorporal de Contrabando , Tracto Gastrointestinal/diagnóstico por imagen , Drogas Ilícitas , Tomografía Computarizada por Rayos X/métodos , Adulto , Cápsulas , Femenino , Humanos , Masculino , Exposición a la Radiación/prevención & control , Estudios Retrospectivos , Turquía
7.
Clinics (Sao Paulo) ; 74: e1337, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31664423

RESUMEN

OBJECTIVES: Nonalcoholic fatty pancreas disease (NAFPD) is characterized by excessive fat deposition in the pancreas in the absence of alcohol consumption. In this study, we aimed to detect a possible relationship between adipose tissue accumulation, prediabetes and diabetes. METHODS: This cross-sectional and retrospective study included 110 patients. Three groups were classified as controls, patients with prediabetes and patients with type 2 diabetes. The abdominal computed tomography (CT) attenuation measurement results of the pancreas were evaluated independently by two experienced radiologists. CT measurements and biochemical parameters were compared between study groups. The relationship between continuous variables was assessed by using one-way ANOVA. To determine the changes in the dependent variable for the effects on study groups, the independent variable was adjusted using ANCOVA. A p-value less than 0.05 was considered statistically significant. RESULTS: The presence of prediabetes and type 2 diabetes was correlated with a decrease in the mean Hounsfield Unit (HU) value of the pancreas (p=0.002). Age was determined to be an independent risk factor and was correlated with NAFPD (p=0.0001). When compared to the controls (p=0.041), 71% of patients with prediabetes and 67% of patients with type 2 diabetes were observed to have an increased incidence of NAFPD. Decreased serum amylase was found to be correlated with the mean HU value of the pancreas (p=0.043). CONCLUSION: NAFPD was independently correlated with both prediabetes and type 2 diabetes adjusted for age (p=0.0001) in this study. Additionally, age was determined to be an independent risk factor and was correlated with NAFPD.


Asunto(s)
Diabetes Mellitus Tipo 2/diagnóstico por imagen , Enfermedades Pancreáticas/diagnóstico por imagen , Adulto , Anciano , Estudios de Casos y Controles , Estudios Transversales , Diabetes Mellitus Tipo 2/complicaciones , Femenino , Humanos , Masculino , Persona de Mediana Edad , Enfermedades Pancreáticas/complicaciones , Estado Prediabético/complicaciones , Estado Prediabético/diagnóstico por imagen , Estudios Retrospectivos , Factores de Riesgo , Tomografía Computarizada por Rayos X
8.
Pol J Radiol ; 84: e498-e503, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-32082446

RESUMEN

PURPOSE: Computed tomography (CT) and positron emission tomography (PET) are the mainstay imaging methods in the evaluation and follow-up of pulmonary nodules. But they both have high radiation risk for patients. Diffusion- weighted magnetic resonance imaging (DW-MRI), on the other hand, is a radiation free imaging method that gives information about the biological structure of tissues at the molecular level by measuring random movement of water in biological tissues. In this prospective study we aimed to compare the computed tomography characteristics of the nodules in terms of malignancy and to compare the accuracy of DW-MRI and PET/CT results in those patients. MATERIAL AND METHODS: Seventy-six patients suspicious for lung cancer on thorax CT imaging were prospectively further evaluated by thorax diffusion-weighted imaging and PET/CT. Pulmonary lesion characteristics, apparent diffusion coefficient (ADC), and maximum standardised uptake values (SUVmax) were compared with histopathological results. RESULTS: There was statistically significant moderate negative correlation between PET-SUVmax and ADC values of lung lesions. ADC values below the cut-off was 97.1%, specificity was 97.6%, positive predictive value was 97.1%, and the negative predictive value was 97.6%. CONCLUSIONS: DAG-MRI and PET/CT have similar success in the differentiation of benign and malignant lung lesions.

9.
Pol J Radiol ; 84: e375-e380, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31969953

RESUMEN

PURPOSE: Quadriceps fat pad is located posterior to the quadriceps tendon. Increased signal intensity of this fat pad is seen on routine knee magnetic resonance imaging (MRI) examinations, but the exact mechanism and related pathologies are not clear. In this study we aimed to evaluate the relationship between MRI signal intensity and morphological features of quadriceps fat pad, as well as various pathologies of the patellofemoral joint. MATERIAL AND METHODS: Sixty-one knees with quadriceps fat pad oedema out of 457 knee MRI examinations were included. Quadriceps fat pad signal intensity, dimensions, posterior indentation, and various parameters related to patellofemoral joint such as trochlear facet asymmetry, trochlear depth and sulcus angle, and the Insall-Salvati ratio were evaluated. RESULTS: There was no statistically significant correlation between quadriceps fat pad oedema intensity and its dimensions, but it was significant when compared to posterior indentation. There was no correlation between fat pad oedema and each of the pathologies. However, there was a significant correlation between the presence of fat pad oedema and the presence of at least one of the pathologies related to patellofemoral joint. CONCLUSIONS: Quadriceps fat pad oedema detected in MRI examinations should warn the radiologist against the presence of various pathologies related to the patellofemoral joint.

10.
Clinics ; 74: e1337, 2019. tab
Artículo en Inglés | LILACS | ID: biblio-1039538

RESUMEN

OBJECTIVES: Nonalcoholic fatty pancreas disease (NAFPD) is characterized by excessive fat deposition in the pancreas in the absence of alcohol consumption. In this study, we aimed to detect a possible relationship between adipose tissue accumulation, prediabetes and diabetes. METHODS: This cross-sectional and retrospective study included 110 patients. Three groups were classified as controls, patients with prediabetes and patients with type 2 diabetes. The abdominal computed tomography (CT) attenuation measurement results of the pancreas were evaluated independently by two experienced radiologists. CT measurements and biochemical parameters were compared between study groups. The relationship between continuous variables was assessed by using one-way ANOVA. To determine the changes in the dependent variable for the effects on study groups, the independent variable was adjusted using ANCOVA. A p-value less than 0.05 was considered statistically significant. RESULTS: The presence of prediabetes and type 2 diabetes was correlated with a decrease in the mean Hounsfield Unit (HU) value of the pancreas (p=0.002). Age was determined to be an independent risk factor and was correlated with NAFPD (p=0.0001). When compared to the controls (p=0.041), 71% of patients with prediabetes and 67% of patients with type 2 diabetes were observed to have an increased incidence of NAFPD. Decreased serum amylase was found to be correlated with the mean HU value of the pancreas (p=0.043). CONCLUSION: NAFPD was independently correlated with both prediabetes and type 2 diabetes adjusted for age (p=0.0001) in this study. Additionally, age was determined to be an independent risk factor and was correlated with NAFPD.


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano , Enfermedades Pancreáticas/diagnóstico por imagen , Diabetes Mellitus Tipo 2/diagnóstico por imagen , Enfermedades Pancreáticas/complicaciones , Estado Prediabético/complicaciones , Estado Prediabético/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Estudios de Casos y Controles , Estudios Transversales , Estudios Retrospectivos , Factores de Riesgo , Diabetes Mellitus Tipo 2/complicaciones
12.
Anesth Essays Res ; 11(2): 390-396, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28663628

RESUMEN

BACKGROUND: Preoperative anxiety may lead to peroperative or postoperative problems when not overcome. AIMS: The aim of this study was to examine the effect of seeking information and other factors on the anxiety of patients preoperatively. SETTINGS AND DESIGN: This study was a prospective, multicentered survey. MATERIALS AND METHODS: Patients scheduled to undergo surgical procedures under spinal anesthesia, preoperatively evaluated as the American Society of Anesthesia 1-3 and where spinal anesthesia was agreed on beforehand, were included. Patients completed State-Trait Anxiety Inventory Scale-State (STAI-S) survey preoperatively. Patients who sought information were also asked to complete the Amsterdam Preoperative Anxiety and Information Scale survey. STATISTICAL ANALYSIS: Quantitative data were compared with one-way ANOVA with post hoc analysis or Kruskal-Wallis test. Comparison of two groups of parameters showing normal distribution was compared using Student's t-test. Comparison of groups versus anxiety was performed using Chi-square and Fisher's exact tests. RESULTS: A total of 330 patients were included. Average STAI-S scores were similar when evaluated for patients' demographic data, gender, marital status, place of residence, type of operation, preoperative fasting time, and comorbidities. University graduates were found to have lower anxiety when compared to other educational statuses. Seeking information from the internet caused a significant decrease in surgical anxiety (P < 0.05) although it had no effect on anesthesia-related anxiety. Interestingly, those seeking information had higher information desire levels compared to patients who had not sought other sources of information (P < 0.05). CONCLUSION: While patients seeking information regarding surgical procedure and/or spinal anesthesia have lower preoperative anxiety levels, their information desire remains high. Apart from detailed information given by the anesthesiologist or surgeon, having access to correct and validated information in multimedia form may decrease anxiety and information desire.

13.
Am J Otolaryngol ; 38(4): 414-416, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28390803

RESUMEN

OBJECTIVE: To evaluate the effect of ET diameter on Chronic Otitis Media (COM) pathogenesis. STUDY DESIGN: Retrospective. SUBJECTS AND METHODS: Patients with unilateral COM disease are included in the study. The connection between fibrocartilaginous and osseous segments of the Eustachian Tube (ET) on axial Computed Tomography (CT) images was defined and the diameter of this segment is measured. The measurements were carried out bilaterally and statistically compared. RESULTS: 154 (76 (49%) male, 78 (51%) female patients were diagnosed with unilateral COM and included in the study. The mean diameter of ET was 1947mm (Std. deviation±0.5247) for healthy ears and 1788mm (Std. deviation±0.5306) for diseased ears. The statistical analysis showed a significantly narrow ET diameter in diseased ear side (p<0.01). CONCLUSION: The dysfunction or anatomical anomalies of ET are correlated with COM. Measuring of the bony diameter of ET during routine Temporal CT examination is recommended for our colleagues.


Asunto(s)
Trompa Auditiva/patología , Otitis Media/diagnóstico por imagen , Otitis Media/etiología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Enfermedad Crónica , Trompa Auditiva/diagnóstico por imagen , Femenino , Humanos , Masculino , Persona de Mediana Edad , Otitis Media/patología , Estudios Retrospectivos , Factores de Riesgo , Tomografía Computarizada por Rayos X , Adulto Joven
14.
Sarcoidosis Vasc Diffuse Lung Dis ; 33(4): 349-354, 2016 Dec 23.
Artículo en Inglés | MEDLINE | ID: mdl-28079847

RESUMEN

 Introduction and aim: Progressive systemic sclerosis (pSS) is a multisystemic connective tissue disease characterized by fibrosis of the skin and internal organs including lung. The mechanisms that leads to progressive lung fibrosis in scleroderma remain obscure. In this study, we aimed to investigate the correlation between HRCT findings and patients' clinical and functional status and the degree of alveolitis based on the BAL resultsMaterials and methods: 65 patients with pSS were evaluated. Thoracic HRCT, pulmonary function tests, and dyspnea measurements were applied, and BAL was performed. The parenchymal abnormalities identified on HRCT were coded, and  scored according to Warrick et al. RESULTS: Among parameters investigated, a correlation was found between the number of segments with subpleural cysts and the duration of disease. Also there was a correlation between the HRCT score and patient age whereas no correlation was detected between the duration of the disease, manifestation of the symptoms, and the x-ray findings. A correlation was found between the percentage of neutrophils detected in BAL and the extent of the honeycombing on HRCT. CONCLUSION: This study showed a strong correlation between the extent of x-ray abnormalities and FVC, RV, and DLCO, as well as an increase in the percentage of BAL fluid neutrophils in patients with SSc-PI.


Asunto(s)
Lavado Broncoalveolar , Pulmón/diagnóstico por imagen , Pulmón/fisiopatología , Fibrosis Pulmonar/diagnóstico , Pruebas de Función Respiratoria , Esclerodermia Difusa/diagnóstico , Tomografía Computarizada por Rayos X , Adulto , Anciano , Anciano de 80 o más Años , Líquido del Lavado Bronquioalveolar/citología , Progresión de la Enfermedad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Neutrófilos , Valor Predictivo de las Pruebas , Capacidad de Difusión Pulmonar , Fibrosis Pulmonar/diagnóstico por imagen , Fibrosis Pulmonar/fisiopatología , Volumen Residual , Esclerodermia Difusa/diagnóstico por imagen , Esclerodermia Difusa/fisiopatología , Índice de Severidad de la Enfermedad , Capacidad Vital
15.
Pak J Med Sci ; 29(2): 560-4, 2013 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-24353576

RESUMEN

OBJECTIVES: The purposes of this study were: (1) to show the impact of chronic low back pain (CLBP) on physical performance, fear avoidance behavior and depressive symptoms in older adults; (2) to describe the relationships between outcome measurements obtained in this study. METHODOLOGY: Ninety-one participants with or without chronic low back pain were included in this study. Only four tests in the Back Performance Scale were used to assess the physical performance of the participants. A Fear Avoidance Beliefs Questionnaire related to physical activity and the Geriatric Depression Scale were also used to examine each subject. RESULTS: The level of performance shown by elderly adults with low back pain was worse than elders without low back pain in the sock test and the pick-up test (p < 0.05). Little correlation between the finger-to-floor test and fear avoidance behaviour related to physical activity was found (p < 0.05). There was little/poor correlation between all performance tests and depressive symptoms (p < 0.05). CONCLUSIONS: The findings indicate that CLBP decreases physical performance, but increases fear avoidance behavior and depressive symptoms in elderly adults. At the same time, it was determined that performance level of elderly adults with back pain was related especially with depressive symptoms.

16.
Agri ; 22(2): 61-7, 2010 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-20582747

RESUMEN

OBJECTIVES: This study was conducted to compare the emotional status and physical activity level in women with chronic widespread pain (CWP) and fibromyalgia (FM). METHODS: Thirty-three women with CWP above the waist, including the upper extremities, and 68 women with FM were evaluated. To determine physical and emotional status, the Fibromyalgia Impact Questionnaire (FIQ), the Experience of Physical Activity Instrument, the Leisure Time Physical Activity Instrument, the Physical Activity at Home and Work Instrument, and the Hospital Anxiety and Depression Scale (HADS) were used. RESULTS: The CWP group had higher physical impairment scores than the FM group (p<0.05); however, the women with FM reported that they felt worse during the previous week than the other group before the interview. They also had higher scores for pain, morning tiredness and depression (FIQ 5, 7 and 10). Emotional symptoms were significantly elevated in FM patients versus the CWP patients. Conversely, no significant differences were found between the groups concerning the health status (FIQ-total) and physical activity (p>0.05). The results indicate that increased pain intensity and spread of pain have negative effects on both physical functioning and emotional status. CONCLUSION: The women with FM reported much more severe clinical symptoms than those with CWP. Therefore, in addition to physical functioning, the emotional status of women with chronic pain should also be evaluated.


Asunto(s)
Ejercicio Físico/fisiología , Fibromialgia/fisiopatología , Dolor/fisiopatología , Adulto , Anciano , Enfermedad Crónica , Ejercicio Físico/psicología , Femenino , Fibromialgia/psicología , Humanos , Actividades Recreativas , Persona de Mediana Edad , Dolor/psicología , Índice de Severidad de la Enfermedad , Estrés Psicológico , Encuestas y Cuestionarios
17.
Intern Med ; 48(19): 1773-4, 2009.
Artículo en Inglés | MEDLINE | ID: mdl-19797836

RESUMEN

Cardiac complications from brucellosis are unusual and usually manifest as endocarditis. The other possible complication is myocardial involvement. Brucella myocarditis and development of heart failure is a very rare complication of brucellosis. We present a patient with new onset heart failure due to brucella myocarditis treated with favorable antibiotic therapy.


Asunto(s)
Brucelosis/complicaciones , Insuficiencia Cardíaca/etiología , Miocarditis/etiología , Animales , Antibacterianos/uso terapéutico , Brucelosis/diagnóstico , Brucelosis/tratamiento farmacológico , Femenino , Insuficiencia Cardíaca/tratamiento farmacológico , Humanos , Persona de Mediana Edad , Miocarditis/tratamiento farmacológico , Zoonosis/etiología
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