Oral features of systemic sclerosis: A case-control study.

OBJECTIVE: The aim of this study was to evaluate the orofacial parameters of systemic sclerosis (SSc) and its related systemic features. SUBJECTS AND METHODS: A descriptive case-control study was performed from November 2015 to October 2016. Ninety-three individuals were included and divided into SSc group (n = 50) and healthy controls (C, n = 43). RESULTS: Systemic sclerosis individuals were mostly women (43/50, 86%), with a mean age of 46 years (±11.6 years). Telangiectasia (42/50, 84%) and reduced mouth opening (35/50, 70%) were the most frequent orofacial findings. The periodontitis frequency was much higher in SSc individuals than in healthy controls (90.7% × 48.83%; p < .001). In addition, SSc individuals presented a distinctive pattern of periodontitis, with low probing pocket depth (2 ± 0.65 mm × 2 ± 0.24; p < .001), higher gingival recession (4 ± 2.13 × 0.14 ± 0,22; p < .001), higher periodontal attachment loss (6 ± 1.34 mm × 2 ± 0.43, p < .001), and lower gingival bleeding index values (7.05 ± 7.25 × 21.57 ± 15.66; p < .001). CONCLUSIONS: Orofacial manifestations were common in SSc and included a unique pattern of periodontal manifestation, characterized by lower gingival bleeding index, higher periodontal attachment loss, and low probing depth.

Nd:YAG laser photocoagulation of benign oral vascular lesions: a case series.

Vascular anomalies of the head and neck are common lesions usually associated with functional and/or aesthetic limitations. The aim of the present paper was to report a case series of oral vascular malformations treated with Nd:YAG laser photocoagulation, highlighting the clinical evolution and post-surgical complications. Fifteen patients diagnosed with oral vascular malformations were treated with Nd:YAG laser followed by three sessions of biostimulation. None of the patients presented post-surgical pain, but 6 of 15 patients (40%) experienced minimal post-surgical complications. All cases presented complete resolution of the lesions after laser treatment. More importantly, 12 out of 15 (80%) resolved after a single session. Low morbidity, minimal patient discomfort, and satisfactory aesthetic results point Nd:YAG laser photocoagulation as a promising option for the management of benign oral vascular lesions.

Oral and genital HPV genotypic concordance between sexual partners.

OBJECTIVES: The aim of this study was to verify human papillomavirus (HPV) transmission and genotype concordance among heterosexual couples. MATERIALS AND METHODS: Thirty-one married couples were evaluated. All male subjects presented with clinically diagnosed HPV-related malignant or potentially malignant lesions and underwent peniscopy and penile swab. Their female counterparts underwent swabs of the uterine cervix and oral mucosa. HPV-DNA detection was performed by polymerase chain reaction and restriction fragment length polymorphism. RESULTS: HPV-DNA was detected in the penis, vagina/cervix, and oral cavity of 16 couples (51.61%). Of these, HPV-DNA concordance was observed in 14 couples (87.5%). HPV-DNA was amplified in penile and oral sites of 14 couples. Of these, 13 couples reported fellatio (92.85%), most of them (10 couples, 76.9%) without condom use. HPV-DNA concordance was observed in 7/10 of these couples (70%). The three couples (100%) who reported use of condom during fellatio were HPV-DNA discordant (p = 0.025). CONCLUSIONS: Lifetime number of female sexual partners and detection of HPV-DNA in the penile mucosa are surrogate markers of exposure to HPV during marriage. Consistent use of condoms may reduce the risk of HPV transmission. CLINICAL RELEVANCE: Oral acquisition of HPV from oro-genital contact is influenced by lack of condom use and previous sexual behavior of the male partner. In addition, oral transmission of the virus due to fellatio is as common as genital transmission.

Seroprevalence of herpes virus associated with the presence and severity of oral mucositis in children diagnosed with acute lymphoid leukemia.

INTRODUCTION: Acute lymphoid leukemia (ALL) is the hematologic neoplasia most commonly diagnosed in children. Among the secondary side effects of chemotherapy, mucositis is the most frequent complication. The aim of this study was to evaluate the seroprevalence of herpes viruses HSV-1, EBV, and CMV and the presence and severity of oral mucositis in children and adolescents diagnosed with ALL. METHODOLOGY: Ninety-two patients diagnosed with ALL were evaluated. Serum samples were collected before chemotherapy and tested by ELISA method. Presence of mucositis was observed on the first day before antineoplastic therapy (D0) and on 7th day post-therapy (D7). Classification of mucositis intensity was performed according to toxicity criteria established by the National Cancer Institute. RESULTS: 70.7% of the patients presented mucositis on the D7, and of these, 60% were classified as Grade I and 40% as Grade II; of the 92 individuals tested, 59 (64.1%) presented antibodies for HSV-1, 57 (62%) for EBV, 75 (81.5%) for CMV_IgG, and 21 (22.8%) for CMV_IgM. Using a logistic regression model, the presence of HSV-1 was observed to be 4.10 times greater in Grade II mucositis severity than in Grade I (P = 0.03). CONCLUSION: Based on the findings of this study, it was possible to conclude that infection by the herpes viruses HSV-1, EBV, and CMV is ubiquitous in the studied population and that HSV-1 may be a risk factor for aggravating the severity of mucositis.

Juvenile Sjögren syndrome: distinctive age, unique findings.

Juvenile Sjögren's syndrome is a rare condition that affects children and adolescents with distinctive clinical features. Parotid swelling usually precedes regular oral and ocular symptoms, while typical serological findings may be absent. Hence, diagnosing juvenile Sjögren's syndrome may be challenging to the attending pediatric dentist, and long-term management without proper diagnosis may be jeopardized. The purpose of this report was to detail the features of an adolescent with primary Sjögren's syndrome diagnosed 12 years after the onset of the disease. An updated literature review highlighted the unusual aspects of the pediatric form of the disease.

Estomatologia: atualização para o clínico geral, parte I: diagnóstico e tratamento das lesões da boca / Oral medicine: atualization for the dentist, part I: diagnosis and treatment of orofacial diseases

O objetivo do presente trabalho é alertar o cirurgião-dentista, mais especificiamente o clínico geral, para os recentes avanços no diagnóstico e tratamento das lesões que acometem a cavidade oral. A literatura pertinente foi revista, com maior ênfase nas referências mais atualizadas. Este artigo inicia uma série, onde as lesões de boca, divididas em grupos de acordo com suas características clínicas, serão abordadas detalhadamente

Estomatologia: atualização para o Clínico geral, parte II: lesÕes brancas da cavidade oral / Oral medicine: an update for the general dental practitioner, part II: oral cavity's white lesions

As lesões brancas mais comumente encontradas na cavidade oral podem ser classificadas de acordo com a etiologia em congênitas e adquiridas, sendo essas últimas divididas em infecciosas e não-infecciosas. O objetivo do presente trabalho é descrever de forma sucinta a etiologia, as características clínicas, o diagnóstico diferencial, o tratamento e o prognóstico das referidas lesões. Foi realizado um levantamento bibliográfico, dando ênfase às citações mais atualizadas

Estomatologia: atualização para o clínico geral, parte III: lesões pigmentadas da cavidade oral / Oral medicine: an update for the general dental practitioner, part III: oral cavity's pigmented lesions

As lesões pigmentadas mais comumente encontradas na cavidade oral podem ser classificadas de acordo com a presença ou ausência de melanina. O objetivo do presente trabalho é descrever de forma sucinta a etiologia, as características clínicas, o diagnóstico diferencial, o tratamento e o prognóstico das referidas lesões. Foi realizado um levantamento bibliográfico, dando ênfase às citaçòes mais atualizadas

Síndrome da boca ardida: uma alternativa terapêutica baseada no uso da vitamina B associada a um neuroregenerador / The burning mouth syndrome: one therapeutic alternative based in the use or vitamine B associate with neuroregeneration

A síndrome da boca ardida é uma condição caracterizada pela sensação de dor e ardor bucal com ausência de sinais clínicos específicos e com mucosa bucal em estado de normalidade, considerada de etiologia variada ou inespecífica, estando relacionada a diversos fatores, dentre eles a avitaminose B, anemia ferropriva, diabetes não-compensada, fatores hormonais (principalmente no climatério e menopausa) e hábitos nocivos à saúde bucal (fumo e álcool). Este trabalho levantou a incidência desta síndrome na clínica de estomatologia da UFPE, durante o período de julho de 1996 a julho de 1997, bem como aplicou uma terapêutica a base de vitamina B associada a um neuroregenerador e observou sua eficácia