RESUMEN
The intraocular penetration of Ciprofloxacin in man: authors have studied the penetration of Ciprofloxacin in the aqueous humor of 30 patients (30 eyes). The concentration in the anterior chamber was on average 0.73 mg/l which is 33% of serum level, from 1.30 hours after a single oral dose of 1000 mg till the 4th hour after this dose. The samples were assessed by a microbiological method. These results are over the minimal inhibitory concentration for many bacterial agents found in endophthalmitis. So this antibiotic may be proposed in the treatment of endophthalmitis. Anyway further investigation is mandatory to assess the safety on efficacy of these antibiotics.
Asunto(s)
Humor Acuoso/química , Ciprofloxacina/farmacocinética , Administración Oral , Anciano , Anciano de 80 o más Años , Ciprofloxacina/administración & dosificación , Ciprofloxacina/sangre , Femenino , Humanos , Masculino , Persona de Mediana EdadRESUMEN
In our daily clinical practice, keratomycosis still remain a challenge for both the ophthalmologist and the laboratory. In this paper simple advices are listed to help us, especially in the topical medical treatment. The emerging role of silver sulfadiazine is pointed out.
Asunto(s)
Antifúngicos/uso terapéutico , Enfermedades de la Córnea/tratamiento farmacológico , Micosis/tratamiento farmacológico , Enfermedades de la Córnea/parasitología , Enfermedades de la Córnea/prevención & control , Humanos , Micosis/prevención & controlRESUMEN
Authors have studied the penetration of ciprofloxacin in the aqueous humor of 30 patients (30 eyes). The concentration in the anterior chamber was on average 0.73 mg/l (33% of serum level), from 1.30 hours after a single oral dose (1000 mg) till the 5th hour after this dose. The samples were assessed by a microbiological method. These results are over the minimal inhibitory concentration for many bacterial agents found in endophthalmitis. So this antibiotic may be proposed in the treatment of endophthalmitis, with further investigations assessing the safety of this procedure.
Asunto(s)
Humor Acuoso/análisis , Ciprofloxacina/farmacocinética , Anciano , Anciano de 80 o más Años , Humor Acuoso/metabolismo , Infecciones Bacterianas/tratamiento farmacológico , Catarata/tratamiento farmacológico , Extracción de Catarata , Ciprofloxacina/análisis , Ciprofloxacina/uso terapéutico , Oftalmopatías/tratamiento farmacológico , Femenino , Humanos , Masculino , Persona de Mediana Edad , PremedicaciónRESUMEN
Choroid osteoma was described for the first time by GASS in 1978. Today only 53 cases were reported in 39 patients. Using 3 new cases recently discovered in our region, we try to assess with the help of the already published data, the main points of the disease and its diagnostic.