Association between Maltreatment, Positive Parent-Child Interaction, and Psychosocial Well-Being in Young Children.

OBJECTIVES: To explore the prevalence of maltreatment and the combined effect of maltreatment and frequency of positive parent-child interaction on psychosocial well-being in young children in China. STUDY DESIGN: A retrospective study was conducted in 2016 in a representative sample of 20 324 children aged 3-4 years who were newly enrolled in kindergartens in Shanghai, China. All data were collected through online platforms. Parents reported the maltreatment history of their children and completed the Strengths and Difficulties Questionnaire and the Chinese Parent-Child Interaction Scale. RESULTS: The prevalence of parent-reported child maltreatment in Shanghai was 2.70% (95% CI, 2.38-3.05). A history of maltreatment increased the risk of total difficulties (aOR, 2.36; 95% CI, 1.39-4.03) and prosocial problems (aOR, 2.31; 95% CI, 1.37-3.91). A high frequency of positive parent-child interaction had a moderating effect on the correlation between maltreatment and prosocial problems. CONCLUSIONS: Maltreated children had an increased risk of developing psychosocial problems, particularly those with a low frequency of positive parent-child interactions. A higher frequency of positive parent-child interactions may be associated with fewer adverse outcomes in maltreated children.

Topical interventions to prevent acute radiation dermatitis in head and neck cancer patients: a systematic review.

PURPOSE: The purpose of the study is to evaluate the effects of pharmacological and non-pharmacological topical controls in the prevention of radiation dermatitis. METHODS: Relevant clinical trials were identified through electronic searching databases CINAHL, CENTRAL, LILACS, PubMed, Scopus, and Web of Science. Handsearching and gray literature searches were also performed to find additional references. Primary outcomes of interest were the development of radiation dermatitis and the time of occurrence of radiation dermatitis. RESULTS: Thirteen randomized clinical trials were included in this review. The trials were published in Chinese, English, or French, from 1980 to 2015. Pharmacological interventions used in the trials were trolamine, aloe vera, allantoin, Lianbai liquid, sucralfate, Na-sucrose octasulfate, olive oil, hialuronic acid, and dexpanthenol. Non-pharmacological topical controls were usual care/institution routine, aqueous cream, mild soap, water thermal gel, placebo, and no intervention. CONCLUSIONS: There was no strong evidence that indicates differences between topical pharmacological interventions or non-pharmacological topical controls in the prevention of acute radiation dermatitis among patients with head and neck cancer undergoing radiotherapy.

The neural basis of motor sequencing: an fMRI study of healthy subjects.

The present study used functional MRI to clarify the brain regions activated during a series of motor sequencing tasks in healthy volunteers. Ten subjects were scanned while performing three soft signs tasks ranging from simple (PT: palm tapping), moderate (PS: pronation/supination) to complex movements (FEP: fist-edge-palm). The FEP task induced significant activations within the cortical networks including bilateral sensorimotor, SMA, left parietal, and right cerebellum, but no activation in the prefrontal area. Moreover, the percentage signal changes within the left sensorimotor, left thalamus and right cerebellum showed an increase in activation with task complexity. The present findings challenge the traditional belief that FEP was a task for frontal lobe function but suggest that successful performance of more complex neurological soft sign tasks like FEP requires the participation of more brain areas than simple motor sequencing and coordination task like PS and PT. These also provide the empirical data on the neural basis of neurological soft signs for further study in other clinical group like schizophrenia in the near future.