1.
Cancer Genet Cytogenet
; 56(1): 7-10, 1991 Oct 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-1747871
RESUMEN
A case of ALL in a 2 1/2-year-old boy with fatal outcome is presented. Cytogenetic analysis revealed a hypodiploid karyotype: 45,X-Y,-2,+der (2)t(Y;2),-12,i(17q),+mar. Some metaphases represented a sideline with 44 chromosomes and monosomy 8 was a consistent anomaly. These findings are rather uncommon in ALL. Hypodiploidy and the translocation, however, indicated poor prognosis in this case.
Asunto(s)
Cromosomas Humanos Par 2 , Leucemia-Linfoma Linfoblástico de Células Precursoras/genética , Translocación Genética , Cromosoma Y , Médula Ósea/patología , Preescolar , Bandeo Cromosómico , Humanos , Cariotipificación , Masculino , Leucemia-Linfoma Linfoblástico de Células Precursoras/patología
2.
Cancer Genet Cytogenet
; 55(2): 173-9, 1991 Sep.
Artículo
en Inglés
| MEDLINE
| ID: mdl-1933820
RESUMEN
Fourteen patients diagnosed as having multiple myeloma were studied cytogenetically. In eight patients a sufficient number of metaphases was obtained and four of them showed abnormal karyotypes of bone marrow cells. Hypodiploidy was a consistent finding, as was the involvement of chromosome 9.
