New steroidal alkaloids from the roots of buxus sempervirens

Phytochemical studies on an EtOH-soluble extract of the roots of Buxus sempervirens of Turkish origin have resulted in the isolation of three new steroidal alkaloids, (+)-semperviraminol (1), (+)-buxamine F (2), and (+)-17-oxocycloprotobuxine (3), along with two known steroidal alkaloids, (+)-buxoxybenzamine (4) and (+)-buxapapillinine (5). The structures of 1-3 were elucidated with the aid of spectroscopic studies. Compounds 4 and 5 exhibited phytotoxic activity against Lemna minor.

Fungal transformation of (1R,2S,5R)-(-)-menthol by cephalosporiumaphidicola

Incubation of (1R,2S,5R)-(-)-menthol (1) with Cephalosporium aphidicola for 12 days yielded the six oxidized metabolites: 10-acetoxymenthol (2), 7-hydroxymenthol (3), 4alpha-hydroxymenthol (4), 3alpha-hydroxymenthol (5), 9-hydroxymenthol (6), and 10-hydroxymenthol (7). The structures of the novel compounds 2, 4, 5, and 7 were assigned by interpretation of their spectral data.

Isolation and structural studies on the chemical constituents of skimmialaureola

Studies on the chemical constituents of the aerial parts of Skimmia laureola have led to the isolation of four new alkaloids, ptelefoliarine (1), acetoxyptelefoliarine (2), acetoxyedulinine (3), and orixiarine (4). Their structures were established by spectroscopic studies.