[Protective effects of vegetable polyphenols on the dynamic metabolism of lipids]. / Efectele protectoare ale polifenolilor vegetali asupra dinamicii metabolismului lipidic.

Epidemiological studies generally showed a strong inverse association between red wine consumption and mortality for coronary heart disease (CHD). Antiatherogenic alteration in plasma lipoproteins, particularly increase in high-density lipoprotein (HDL) cholesterol, is considered as the most plausible mechanism of the protective effect of alcohol consumption on CHD. The aim of our study was to investigate the in vivo effects of regular consumption of 300 ml red wine/day, for three weeks, on human serum lipid profile. Thirty healthy volunteers on no medication, abstained from alcohol for 21 days prior the study, were included in our study, and blood samples were taken for serum lipids at base line and after 21 days of wine consumption. This study confirmed that moderate consumption of red wine exerts cardioprotective effects through beneficial changes in lipid profile.