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1.
Clin Pediatr (Phila) ; 61(12): 850-858, 2022 12.
Artículo en Inglés | MEDLINE | ID: mdl-35773977

RESUMEN

Licensed behavioral health providers (LBHPs) were integrated into 5 pediatric primary care practices in southeast and east Texas from October 2018 through March 2020. LBHPs Licensed behavioral health providers across the sites were 3 licensed clinical social workers (LCSW), 1 psychologist, and 1 nurse practitioner (NP). Practices provided data for 6 to 15 months. Overall, 2769 units of behavioral health services were provided to 746 children over 2243 hours. Across 4 sites, 44.3% of behavioral health patients were diagnosed with trauma disorders, 22.1% with anxiety, 19.3% with attention-deficit hyperactivity disorder, 15.1% with depression, and 10.9% with disruptive behavior disorders. Overall, the model was financially successful at 2 sites (LCSWs) and unsuccessful at 1 site (NP). The other 2 sites demonstrated potential for financial sustainability with increased behavioral health patient volume. Overall, this model is a financially viable option for pediatric primary care practices with adequate patient volumes to provide integrated behavioral health services.


Asunto(s)
Trastorno por Déficit de Atención con Hiperactividad , Atención Primaria de Salud , Niño , Humanos , Déficit de la Atención y Trastornos de Conducta Disruptiva , Ansiedad , Texas
2.
J Bacteriol ; 177(18): 5322-6, 1995 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-7665521

RESUMEN

Homologs of ntrB and ntrC genes from Rhodospirillum rubrum were cloned and sequenced. A mutant lacking ntrBC was constructed, and this mutant has normal nitrogenase activity under nif-derepressing conditions, indicating that ntrBC are not necessary for the expression of the nif genes in R. rubrum. However, the post-translational regulation of nitrogenase activity by ADP-ribosylation in response to NH4+ was partially abolished in this mutant. More surprisingly, the regulation of nitrogenase activity in response to darkness was also affected, suggesting a physiological link between the ntr system and energy signal transduction in R. rubrum. The expression of glutamine synthetase, as well as its posttranslational regulation, was also altered in this ntrBC mutant.


Asunto(s)
Proteínas Bacterianas/genética , Proteínas de Unión al ADN/genética , Genes Bacterianos , Fijación del Nitrógeno/genética , Nitrogenasa/metabolismo , Fosfoproteínas Fosfatasas/genética , Proteínas Quinasas/genética , Proteínas de Unión al ARN , Rhodospirillum rubrum/genética , Transactivadores , ADP Ribosa Transferasas/metabolismo , Secuencia de Aminoácidos , Clonación Molecular , Oscuridad , Regulación Bacteriana de la Expresión Génica/genética , Glutamato-Amoníaco Ligasa/biosíntesis , Datos de Secuencia Molecular , Mutación , Proteínas PII Reguladoras del Nitrógeno , Compuestos de Amonio Cuaternario/farmacología , Rhodospirillum rubrum/enzimología , Análisis de Secuencia de ADN , Eliminación de Secuencia , Transducción de Señal , Factores de Transcripción/genética
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