RESUMEN
We report two cases of acute rhabdomyolysis due to severe hypokalemia. The first case appears to be caused by a chronic dietary potassium deficiency, responsible also for the elevation of blood pressure and the impairment of myocardial contractility. The administration of hydrochlorothiazide, albeit associated with captopril, could have decompensated the potassium balance, thus precipitating the acute rhabdomyolysis. More commonly the second case is due to acute potassium losses induced by a trivial enteritis in a hypertensive patient who was taking thiazide diuretics for a long period of time. We emphasize that chronic dietary potassium deficiency may represent a predisposing variable to acute rhabdomyolysis, which is generally precipitated by the superimposition of other potassium lowering factors.
Asunto(s)
Hipopotasemia/complicaciones , Rabdomiólisis/etiología , Enfermedad Aguda , Anciano , Dieta , Femenino , Humanos , Hidroclorotiazida/efectos adversos , Hipopotasemia/inducido químicamente , Hipopotasemia/etiología , MasculinoRESUMEN
Ethanol and/or its metabolites interfere with the chromatographic assay of glycated hemoglobins. Fasting plasma glucose, blood ethanol, HbA(1), HbA(1c), HbA(1a+b), MCV and GGT were determined in 22 control subjects; 22 alcoholics, 22 diabetic patients and 22 alcoholic diabetic patients. Fasting plasma glucose and all hemoglobin fractions were lower in alcoholic subjects and, except for HbA(1a+b), higher in diabetic patients and in alcoholic diabetic patients. HbA(1), and HbA(1c) correlated well with plasma glucose but not with blood ethanol, MCV and GGT. Glycated hemoglobin was not found to be a useful marker for alcohol abuse. With the chromatographic method we used, the evaluation of glycated hemoglobin fractions, chiefly HbA(1c), confirms its usefulness in monitoring the metabolic control of diabetic subjects, even in case of ethanol abuse.
Asunto(s)
Consumo de Bebidas Alcohólicas , Alcoholismo/sangre , Diabetes Mellitus/sangre , Etanol/sangre , Hemoglobina Glucada/análisis , Alcoholismo/complicaciones , Glucemia/análisis , Diabetes Mellitus Tipo 1/sangre , Diabetes Mellitus Tipo 1/complicaciones , Diabetes Mellitus Tipo 2/sangre , Diabetes Mellitus Tipo 2/complicaciones , Ayuno , Femenino , Humanos , Masculino , Persona de Mediana EdadRESUMEN
A case of renal clear-cell carcinoma presenting as a nodular thyroid metastasis is reported. The possibility of a metastatic lesion from the kidney should be taken into account in each case of clear-cell thyroid lesion. Fine needle aspiration cytology may be unable to discriminate between the renal or thyroid origin of such lesions unless PAS staining is performed.
