RESUMEN
OBJECTIVE: This study explored the therapeutic approaches used for end-of-life (EOL) patients admitted to the emergency department (ED) and examined whether the decision to perform life-extending treatment (LET) or to allow natural death (AND) depends on patient characteristics, medical staff variables, and ED setting. METHODS: A retrospective archive study was conducted from January 2015 to December 2017 in the ED of a tertiary hospital. The study sample were 674 EOL patients who had died in the ED. For each patient, data were collected and measured for dying process (LET vs. AND), patient characteristics, ED-setting variables, and medical-staff characteristics. RESULTS: The proportion of EOL patients undergoing LET increased from 18.1% in 2015 to 25.9% in 2016 and to 30.3% in 2017 (pâ¯=â¯.010), and a quarter of them were treated by emergency medical services. Males tended to receive LET more than females (pâ¯<â¯.001). An association was found between Jewish physicians and nurses and AND (pâ¯=â¯.001). Heavier workload in the ED and greater severity of the triage classification predicted more LET (OR-1.67, CIâ¯=â¯1.05-1.76, pâ¯=â¯.003 and ORâ¯=â¯1.42, CI-0.60-0.81, pâ¯<â¯.001, respectively). Receiver operating characteristic analysis showed that patient characteristics contributed most crucially to the therapeutic approaches (C statistic 0.624-0.675, CI-0.62-0.71). CONCLUSIONS: The therapeutic approach used for EOL patients in the ED depends on variables in all three treatment layers: patient, medical staff, and ED setting. Applicable national programs should be developed to ensure that no external factors influence the dying-process decision.
Asunto(s)
Toma de Decisiones , Servicio de Urgencia en Hospital/estadística & datos numéricos , Privación de Tratamiento/normas , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Servicio de Urgencia en Hospital/organización & administración , Femenino , Humanos , Lactante , Judaísmo , Modelos Logísticos , Masculino , Persona de Mediana Edad , Curva ROC , Estudios Retrospectivos , Cuidado Terminal/métodos , Cuidado Terminal/normas , Cuidado Terminal/estadística & datos numéricos , Privación de Tratamiento/estadística & datos numéricosRESUMEN
Paroxysmal atrial fibrillation (AF), a frequent cause of repeated hospitalization, is effectively treated with propafenone. The time to conversion to sinus rhythm is a consideration when managing AF in the emergency room. We investigated the conversion rates of paroxysmal AF by 3 different oral propafenone (P) regimens, in terms of time to conversion. 188 patients with onset of AF within 48 hours were treated with propafenone (P): 48 received 600 mg as a first oral dose followed after 8 hrs by 150 mg (Group A); 82 received 300 mg as a first dose, followed by the same dose 3 and again 8 hrs later (B); 58 received 150 mg every 3 hrs, up to a total dose of 600 mg (C). P was stopped when sinus rhythm was achieved. Rates of conversion to sinus rhythm after 3 hrs in the 3 groups were: 46%, 41% and 26% respectively; after 8 hrs: 77%, 78% and 70%; and after 12 hrs: 81%, 84% and 76%. Treatment was discontinued in 8. There was excessive QRS widening (> 25% of the basal value) in 1 in group A, 1 in group B and 2 in group C; wide-QRS tachycardia occurred in 4 in group B. In Group A there was a higher rate of early successful conversion, with a lower incidence of side-effects than with the other regimens.