Asunto(s)
Anomalías Múltiples/genética , Anomalías Múltiples/patología , Deformidades Congénitas de la Mano/genética , Deformidades Congénitas de la Mano/patología , Pérdida Auditiva Sensorineural/genética , Pérdida Auditiva Sensorineural/patología , Discapacidad Intelectual/genética , Queratodermia Palmoplantar/genética , Queratodermia Palmoplantar/patología , Adolescente , Niño , Femenino , Humanos , Masculino , Linaje , HermanosRESUMEN
Acquired Blaschkoid dermatitis characterised by unilateral relapsing inflammatory disease along the lines of Blaschko. A 40-year-old Indian male presented with unilateral erythematous, itchy grouped papules on the left side of the chest, abdomen, back and left arm of 15 days duration. The eruption stopped abruptly at the midline of the torso, completely sparing the right side of the body. The lesions were arranged in whorls and streaks corresponding to the lines of Blaschko. Skin biopsy showed hyperkeratosis and features suggestive of sub-acute spongiotic dermatitis with lymphocytic infiltrate around the blood vessels in the dermis. Patient was diagnosed as a case of Blaschkoid dermatitis. To the best of our knowledge, this is the first case of this condition being reported from India.
Asunto(s)
Dermatitis/patología , Enfermedades Cutáneas Papuloescamosas/patología , Adulto , Biopsia , Ciproheptadina/uso terapéutico , Dermatitis/tratamiento farmacológico , Fármacos Dermatológicos/uso terapéutico , Glucocorticoides/uso terapéutico , Antagonistas de los Receptores Histamínicos H1/uso terapéutico , Humanos , Hidrocortisona/análogos & derivados , Hidrocortisona/uso terapéutico , Queratosis/patología , Linfocitos/patología , Masculino , Prednisolona/uso terapéutico , Piel/patología , Enfermedades Cutáneas Papuloescamosas/tratamiento farmacológicoRESUMEN
Two cases of Ehlers-Danlos syndrome affecting two real brothers are being reported. Both of them presented with features of atrophy and hyperextensibility of skin, hypermobility of joints and scarring at the sites of trauma. The elder brother also had kyphoscoliosis and hypogonadism with testicular failure.
Asunto(s)
Síndrome de Ehlers-Danlos/diagnóstico , Síndrome de Ehlers-Danlos/genética , Predisposición Genética a la Enfermedad , Adolescente , Estudios de Seguimiento , Deformidades Congénitas de la Mano/diagnóstico , Humanos , Hipogonadismo/diagnóstico , Hipogonadismo/genética , Cifosis/diagnóstico , Cifosis/genética , Masculino , Medición de Riesgo , Índice de Severidad de la Enfermedad , HermanosRESUMEN
Cicatricial pemphigoid (CP) occurring in a 60-year-old male is described. He had involvement of conjunctival, nasal and oral mucosae, in addition to skin lesions. Diagnosis was confirmed by histopathology. He responded well to oral steroids and dapsone. However, vision in one eye was lost.
Asunto(s)
Gelatina , Hemoglobinas , Lactoglobulinas , Sales (Química) , Agua , Animales , Bovinos , Fenómenos Químicos , QuímicaAsunto(s)
Electrólitos , Albúmina Sérica Bovina , Agua , Unión Proteica , Desnaturalización Proteica , TermodinámicaRESUMEN
Data on 30 three-way maize (Zea mays L.) hybrids formed from 5 inbred lines were subjected to the combining ability type of analysis. The relative importance of general and specific line effects in maize three-way hybrids was studied by the Ponnuswamy and Das (1973) method. It was also shown that this analysis provides the breeder with the basic information necessary to choosing proper breeding materials and in deciding the order in which they should be combined to get desirable three-way hybrids.