[The trace element status in patients with chronic hepatic diseases]. / Osobennosti élementnogo statusa pri khronicheskikh zabolevaniiakh pecheni.

Despite of the achievements of pharmacology it is very actually to improve the diagnosis and therapy of different chronic hepatic diseases. The purpose of the investigation is to study trace element (TE) status in patients with chronic hepatic diseases for estimating the possibility of therapy efficiency improvement. 102 patients with chronic hepatic diseases, aged from 19 to 60 were clinically and laboratory investigated. Group 1 (36 patients) suffered from alcoholic liver cirrhosis, group 2 (35 patients) had chronic alcoholic steatohepatitis and group 3 (31 patients) had non-alcoholic steatohepatitis (NASH). Multielement blood plasma analysis by ICP-MS and ICP-OES was perfomed in the Center of Biotic Medicine (Moscow). The results showed the significant changes in TE status in patients with chronic hepatic diseases that proves the expediency of studying both the essential and toxic element in such patients to improve the diagnosis and to optimize the treatment. Patients with chronic hepatic diseases are characterized by changing of such elements as Al, Ca, Cu, K, Se, Zn, that leads to necessity of using them for diagnosis.

[The treatment of patients with long-term nonhealing duodenal ulcers combined with chronic gastric erosions in the presence of Helicobacter pylori]. / Lechenie bol'nykh s dlitel'no ne zazhivaiushchimi iazvami dvenadtsatiperstnoi kishki v sochetanii s khronicheskimi éroziiami zheludka pri nalichii Helicobacter pylori.

Data are reported of the efficacy of different drugs in the treatment 66 patients with prolonged nonhealing duodenal ulcers in association with chronic erosions in the presence of Helicobacter pylori. It was found that a concentrate of granulocytes and de-nol proved most efficient while trichopol and furazolidone were of minor efficacy.

[The humoral and cellular immunity indices of patients with long-term nonhealing stomach ulcers with the presence of Campylobacter pylori]. / Pokazateli gumoral'nogo i kletochnogo immuniteta u bol'nykh s dlitel'no nezazhivaiushchimi iazvami zheludka pri nalichii Campylobacter pylori.

The authors relate the data on humoral and cellular immunity in patients with long nonhealing gastric ulcers. It has been shown that if these patients have Campylobacter pylori, there are no specific differences in the response of the immune system. During cicatrization, positive changes can be seen, namely an increase of T helper and decrease of suppressor activity of T lymphocytes together with a decline of the content of IgA and IgG.