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1.
Rev. méd. Chile ; 143(11): 1490-1493, nov. 2015. tab
Artículo en Español | LILACS | ID: lil-771738

RESUMEN

Bleeding disorders are commonly associated with hemato-oncologic diseases. We report a 68 years old male with a chronic myelomonocytic leukemia derived from a long lasting mielodysplastic syndrome that did not respond to treatment with Azacitidine. The patient was hospitalized due to tonic clonic seizures. A CAT scan showed a hematoma in the frontal lobe. A new assessment of hemostasis revealed an isolated deficiency of Factor X. We speculate that this deficit could be secondary to consumption due to the chronic Myelomonocytic Leukemia.


Asunto(s)
Anciano , Humanos , Masculino , Deficiencia del Factor X/etiología , Lóbulo Frontal/lesiones , Leucemia Mielomonocítica Crónica/complicaciones , Antimetabolitos Antineoplásicos/uso terapéutico , Azacitidina/uso terapéutico , Deficiencia del Factor X/diagnóstico , Hematoma/diagnóstico , Leucemia Mielomonocítica Crónica/tratamiento farmacológico , Leucocitos , Monocitos , Convulsiones/complicaciones
2.
Rev Med Chil ; 143(11): 1490-3, 2015 Nov.
Artículo en Español | MEDLINE | ID: mdl-26757875

RESUMEN

Bleeding disorders are commonly associated with hemato-oncologic diseases. We report a 68 years old male with a chronic myelomonocytic leukemia derived from a long lasting mielodysplastic syndrome that did not respond to treatment with Azacitidine. The patient was hospitalized due to tonic clonic seizures. A CAT scan showed a hematoma in the frontal lobe. A new assessment of hemostasis revealed an isolated deficiency of Factor X. We speculate that this deficit could be secondary to consumption due to the chronic Myelomonocytic Leukemia.


Asunto(s)
Deficiencia del Factor X/etiología , Lóbulo Frontal/lesiones , Leucemia Mielomonocítica Crónica/complicaciones , Anciano , Antimetabolitos Antineoplásicos/uso terapéutico , Azacitidina/uso terapéutico , Deficiencia del Factor X/diagnóstico , Hematoma/diagnóstico , Humanos , Leucemia Mielomonocítica Crónica/tratamiento farmacológico , Leucocitos , Masculino , Monocitos , Convulsiones/complicaciones
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