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3.
Pol J Pharmacol Pharm ; 33(4): 401-6, 1981 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-7329865

RESUMEN

Experimental atherosclerosis was produced in domestic pigs by administration for 24 weeks a high lipid diet containing cholesterol and coconut oil. ECG changes were not uniform: negative T, prolonged intraventricular conduction, and premature ventricular beats were observed. Macroscopic and microscopic anatomo-pathological studies revealed atheromatous changes in the aorta.


Asunto(s)
Arteriosclerosis/fisiopatología , Animales , Arteriosclerosis/patología , Dieta Aterogénica , Electrocardiografía , Femenino , Frecuencia Cardíaca , Masculino , Miocardio/patología , Porcinos
5.
Arch Immunol Ther Exp (Warsz) ; 27(1-2): 29-36, 1979.
Artículo en Inglés | MEDLINE | ID: mdl-444042

RESUMEN

Results of immunologic and histologic studies on rabbits immunized with sheep red blood cells (SRBC) showed dependence of the immunologic response (PFC, RFC) on the histologic structure of the spleen, particularly width of the sinusoidal vessels. Histologic changes in the spleen are a result of immunization and their intensity is related to the dose of antigen. The influence of dosage of antigen and histologic structure of the spleen on regulation of the immunologic response are discussed.


Asunto(s)
Formación de Anticuerpos , Eritrocitos/inmunología , Bazo/inmunología , Animales , División Celular , Relación Dosis-Respuesta Inmunológica , Femenino , Inmunización , Memoria Inmunológica , Masculino , Conejos , Ovinos , Bazo/citología
6.
Med Pr ; 28(3): 179-87, 1977.
Artículo en Polaco | MEDLINE | ID: mdl-197373

RESUMEN

Male rats weighing 180-220 g were given CdSO4, 0,4 mg/kg body weight subcutaneously once a week for 6-12 months. The animals were killed after 6, 9, 12 months and following blood serum levels were determined: total protein, albumin, globulin, GPT, GOT, Al.P. and urea. The tissue tissue samples from liver and kidneys were examined histologically (acid and alkaline phosphatase). After 9 months, the difference between values of biochemical indices in the exposed and control groups was statistically significant. It has been found that the observed biochemical indices show correlation with the extent of morphological changes in liver and kidneys. These degenerative changes became more intense in the liver than in the kidneys.


Asunto(s)
Intoxicación por Cadmio/patología , Riñón/patología , Hígado/patología , Animales , Proteínas Sanguíneas/análisis , Enfermedad Crónica , Histocitoquímica , Riñón/enzimología , Hígado/enzimología , Masculino , Monoéster Fosfórico Hidrolasas/metabolismo , Ratas , Albúmina Sérica/análisis , Transaminasas/sangre , Urea/sangre
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