1.
Ann Pharm Fr
; 58(3): 180-6, 2000 May.
Artículo
en Francés
| MEDLINE
| ID: mdl-10844279
RESUMEN
1,4,2-dioxazine derivatives were synthesized from B-uréidoxyalcools, and their 1H, 13C RMN and mass spectra were determined. Their activity against human immunodeficiency virus and their cytotoxicity were then evaluated. Whereas the derivatives had no effect on virus infectivity nor on reverse transcriptase activity, they unexpectedly enhanced host cell infection by both lymphotropic and macrophage-tropic virus strains.
Asunto(s)
Fármacos Anti-VIH/síntesis química , Fármacos Anti-VIH/farmacología , Oxazinas/síntesis química , Oxazinas/farmacología , Supervivencia Celular/efectos de los fármacos , Transcriptasa Inversa del VIH/antagonistas & inhibidores , VIH-1/patogenicidad , Humanos
2.
AIDS Res Hum Retroviruses
; 16(1): 87-9, 2000 Jan 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-10628820
Asunto(s)
Frecuencia de los Genes , Receptores CCR5/genética , Alelos , Femenino , Humanos , Masculino , Marruecos
3.
AIDS
; 11(14): 1781-3, 1997 Nov 15.
Artículo
en Inglés
| MEDLINE
| ID: mdl-9386816