Disorders of the immune system in severely burned patients.

This paper analyses the results of immunological examinations of 124 patients with thermal injury. We examined indices of peripheral blood such us the size of the population of circulating T-lymphocytes (CD3), T-helpers (CD4), T-suppressors (CD8 and CD25), natural cell killers (CD16), transmembrane protein of apoptotic activity (CD16), B-lymphocytes, phagocyte activity of lymphocytes, and the level of serum antibody of the basic classes (Ig G, A, M). It was discovered that the burn disease was accompanied by deeply marked secondary immune deficiency primarily caused by all components of the active suppression of the cellular link of the immune system and reduction of phagocyte activity of neutrophils.

Surgical treatment of deep burns.

The results are presented of the treatment of 168 patients aged 1 to 60 yr with deep burns. The use of active surgical tactics in patients with deep and extensive burns was tested. It was found that the application of a method of active surgical tactics, in combination with different approaches of wound covering such as "combined auto- and allografting", "combined auto- and porcine-skin grafting", and "combined autografting with cultivated allofibroblast cell culture usage", reduced purulent-septic complications and improved the results of treatment.