[Apixaban in the treatment of venous thrombosis associated with permanent pacemaker implantation]. / Apixaban en el tratamiento de trombosis venosa asociada a implante de marcapasos definitivo.

Venous thromboembolism is the third vascular disease in morbidity and mortality. The new oral anticoagulants are presented as an effective and safe alternative to conventional antithrombotic therapy. Apixaban has been recently approved to use for the treatment of deep vein thrombosis. A case of an elderly patient, with high risk of bleeding, a history of cancer, and recent pacemaker implant, who consulted for superficial venous thrombosis of the ipsilateral arm to the implant, which was successfully treated with apixaban is here presented.

Arrhythmias in a patient with sarcoidosis.

Arrhythmias in a Patient With Sarcoidosis. Sarcoidosis is a multisystemic granulomatous disease of unknown etiology; up to 27% of cases entail cardiac involvement. Conduction abnormalities and ventricular tachycardia are the most common arrhythmias and can cause sudden death. We describe a patient who developed cardiac sarcoidosis 9 years after undergoing surgery for neurosarcoidosis. He presented with 2:1 second-degree atrioventricular block. Ventricular tachycardia with 3 morphologies was induced by exercise stress test. A DDD pacer/implantable cardioverter defibrillator (ICD) was implanted, which prevented exercise-induced ventricular tachycardia in a follow-up stress test. Treatment with steroids was initiated. The AVB disappeared, and no further arrhythmias were documented at the 1-year follow-up.